FORM 4 [ ] Check this box if no longer subject to Section 16. Form 4 or Form 5 obligations may continue. See Instruction 1(b).         
UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549

STATEMENT OF CHANGES IN BENEFICIAL OWNERSHIP OF SECURITIES
                                                                                  
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Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934 or Section 30(h) of the Investment Company Act of 1940
                      

1. Name and Address of Reporting Person *

Burton Karen L
2. Issuer Name and Ticker or Trading Symbol

STERIS plc [ STE ]
5. Relationship of Reporting Person(s) to Issuer (Check all applicable)

_____ Director                    _____ 10% Owner
__X__ Officer (give title below)    _____ Other (specify below)
VP, Controller & CAO
(Last)          (First)          (Middle)

C/O 70 SIR JOHN ROGERSON'S QUAY
3. Date of Earliest Transaction (MM/DD/YYYY)

11/5/2020
(Street)

DUBLIN, L2 2
(City)        (State)        (Zip)
4. If Amendment, Date Original Filed (MM/DD/YYYY)

 
6. Individual or Joint/Group Filing (Check Applicable Line)

_X _ Form filed by One Reporting Person
___ Form filed by More than One Reporting Person

Table I - Non-Derivative Securities Acquired, Disposed of, or Beneficially Owned
1.Title of Security
(Instr. 3)
2. Trans. Date 2A. Deemed Execution Date, if any 3. Trans. Code
(Instr. 8)
4. Securities Acquired (A) or Disposed of (D)
(Instr. 3, 4 and 5)
5. Amount of Securities Beneficially Owned Following Reported Transaction(s)
(Instr. 3 and 4)
6. Ownership Form: Direct (D) or Indirect (I) (Instr. 4) 7. Nature of Indirect Beneficial Ownership (Instr. 4)
Code V Amount (A) or (D) Price
Ordinary Shares 11/5/2020  M  2852 A$0.00 10746 D  
Ordinary Shares 11/5/2020  S  2852 D$179.38 (1)7894 D  
Ordinary Shares 11/5/2020  S  1750 D$179.48 (2)6144 (3)D  

Table II - Derivative Securities Beneficially Owned (e.g., puts, calls, warrants, options, convertible securities)
1. Title of Derivate Security
(Instr. 3)
2. Conversion or Exercise Price of Derivative Security3. Trans. Date3A. Deemed Execution Date, if any4. Trans. Code
(Instr. 8)
5. Number of Derivative Securities Acquired (A) or Disposed of (D)
(Instr. 3, 4 and 5)
6. Date Exercisable and Expiration Date7. Title and Amount of Securities Underlying Derivative Security
(Instr. 3 and 4)
8. Price of Derivative Security
(Instr. 5)
9. Number of derivative Securities Beneficially Owned Following Reported Transaction(s) (Instr. 4)10. Ownership Form of Derivative Security: Direct (D) or Indirect (I) (Instr. 4)11. Nature of Indirect Beneficial Ownership (Instr. 4)
CodeV(A)(D)Date ExercisableExpiration DateTitleAmount or Number of Shares
Employee Stock Option (right to buy) $66.15 11/5/2020  M   2852     (4)5/28/2025 Ordinary Shares 2852 $0.00 0 D  

Explanation of Responses:
(1) Price reflects a weighted average sale price for multiple transactions ranging from $179.05 to $179.78 per share, inclusive. The Reporting Person undertakes to provide, upon request by the SEC Staff, the Issuer or a security holder of the Issuer, full information regarding the number of shares sold at each separate price.
(2) Price reflects a weighted average sale price for multiple transactions ranging from $179.40 to $179.70 per share, inclusive. The Reporting Person undertakes to provide, upon request by the SEC Staff, the Issuer or a security holder of the Issuer, full information regarding the number of shares sold at each separate price.
(3) 6,144 of these ordinary shares are restricted. The restrictions on these ordinary shares lapse as follows: 3,000 on June 1, 2021; 1,332 on May 31, 2022; 396 on June 1, 2022; 765 on May 31, 2022; 255 on May 31, 2023; 198 on June 1, 2023 and 198 on June 3, 2024.
(4) This option to purchase 2,852 STERIS ordinary shares, which are fully vested, which was received in conjunction with the Redomiciliation of the entity organized under the laws of the U.K. and formerly named STERIS plc ("Old STERIS") in exchange for an option to purchase 2,852 Old STERIS ordinary shares for $66.15 per share, subject to the same terms and conditions as the original Old STERIS stock option, except as otherwise required by law.

Reporting Owners
Reporting Owner Name / Address
Relationships
Director10% OwnerOfficerOther
Burton Karen L
C/O 70 SIR JOHN ROGERSON'S QUAY
DUBLIN, L2 2


VP, Controller & CAO

Signatures
/s/ Ronald E. Snyder, Authorized Representative under Power of Attorney11/9/2020
**Signature of Reporting PersonDate

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