NOTICE OF ANNUAL MEETING OF STOCKHOLDERS
To Be Held at 9:00 a.m. Pacific Time on Wednesday, June 16, 2021
Dear Stockholders of Twilio Inc.:
We cordially
invite you to attend the 2021 annual meeting of stockholders (the Annual Meeting) of Twilio Inc., a Delaware corporation, which will be held virtually on Wednesday, June 16, 2021 at 9:00 a.m. Pacific
Time via live audio webcast on the Internet at www.virtualshareholdermeeting.com/TWLO2021, for the following purposes, as more fully described in the accompanying proxy statement:
1. To elect three Class II directors to serve until the 2024 annual meeting of stockholders and
until their successors are duly elected and qualified;
2. To ratify the appointment of KPMG LLP as
our independent registered public accounting firm for our fiscal year ending December 31, 2021;
3. To conduct a non-binding advisory vote to approve the
compensation of our named executive officers; and
4. To transact such other business as may properly
come before the Annual Meeting or any adjournments or postponements thereof.
The Annual Meeting will be held entirely online due to the COVID-19 pandemic and to support the health and well-being of our employees, stockholders, directors and community. You will be able to attend the meeting, vote and submit your questions during the meeting at
www.virtualshareholdermeeting.com/TWLO2021. As always, we encourage you to vote your shares prior to the Annual Meeting either by telephone, Internet or by proxy card to help make this meeting format as efficient as possible.
Our board of directors has fixed the close of business on April 19, 2021 as the record date for the Annual Meeting. Only stockholders of
record on April 19, 2021 are entitled to notice of and to vote at the Annual Meeting. A list of stockholders of record will be available for inspection by stockholders of record during normal business hours for ten days prior to the Annual
Meeting for any legally valid purpose at our corporate headquarters at 101 Spear Street, First Floor, San Francisco, California 94105. For access to the stockholder list, please contact us at legalnotices@twilio.com. The stockholder list will also
be available during the Annual Meeting at www.virtualshareholdermeeting.com/ TWLO2021. Further information regarding voting rights and the matters to be voted upon are presented in the accompanying proxy statement.
Important Notice Regarding the Availability of Proxy Materials for the Annual Meeting to Be Held on Wednesday, June 16,
2021, at 9:00 a.m. Pacific Time via live audio webcast at www.virtualshareholdermeeting.com/TWLO2021: On or about April 29, 2021, we expect to mail to our stockholders a Notice of Internet Availability of Proxy Materials (the
Notice) containing instructions on how to access our proxy statement for our Annual Meeting (the Proxy Statement) and our Annual Report on Form 10-K for the fiscal year
ended December 31, 2020 (the Annual Report) and vote online. The Proxy Statement and the Annual Report can be accessed directly at the following Internet address: http://materials.proxyvote.com/90138F. All you have to do is
enter your 16-digit control number located on your proxy card. If you attend the Annual Meeting virtually, you may withdraw your proxy and vote online during the Annual Meeting if you so choose. The Notice
also contains instructions on how each of our stockholders can receive a paper copy of our proxy materials, including the Proxy Statement, Annual Report and a form of proxy card or voting instruction form. All stockholders who do not receive the
Notice, including stockholders who have previously requested to receive paper copies of proxy materials, will receive a paper copy of the proxy materials by mail unless they have previously requested delivery of proxy materials electronically.
Please note, however, that if your shares are held of record by a broker, bank, or other nominee and you wish to vote at the meeting, you must obtain a proxy issued in your name from that record holder.
YOUR VOTE IS IMPORTANT. Whether or not you plan to attend the Annual Meeting, we urge you to submit your vote via the Internet, telephone or
mail as soon as possible to ensure that your shares are represented. For additional instructions on voting by telephone or the Internet, please refer to your proxy card. Returning the proxy does not deprive you of your right to attend the Annual
Meeting and to vote your shares at the Annual Meeting.
We appreciate your continued support of Twilio.
By order of the board of directors,
Jeff Lawson
Co-Founder, Chief Executive Officer and Chairperson of the Board
San Francisco, California
April 22, 2021