FORM 4
[ X ] Check this box if no longer subject to Section 16. Form 4 or Form 5 obligations may continue. See Instruction 1(b).         
UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549

STATEMENT OF CHANGES IN BENEFICIAL OWNERSHIP OF SECURITIES
                                                                                  
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Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934, Section 17(a) of the Public
Utility Holding Company Act of 1935 or Section 30(f) of the Investment Company Act of 1940
                      

1. Name and Address of Reporting Person *

CARTER DAVID WARREN 		2. Issuer Name and Ticker or Trading Symbol

CALIPER LIFE SCIENCES INC [ CALP ] 		5. Relationship of Reporting Person(s) to Issuer (Check all applicable)

__ X __ Director                      _____ 10% Owner
_____ Officer (give title below)      _____ Other (specify below)
(Last)          (First)          (Middle)

68 ELM STREET 		3. Date of Earliest Transaction (MM/DD/YYYY)

11/7/2011
(Street)

HOPKINTON, MA 01748
(City)        (State)        (Zip)
4. If Amendment, Date Original Filed (MM/DD/YYYY)

 
6. Individual or Joint/Group Filing (Check Applicable Line)

_ X _ Form filed by One Reporting Person
___ Form filed by More than One Reporting Person

Table I - Non-Derivative Securities Acquired, Disposed of, or Beneficially Owned
1.Title of Security
(Instr. 3) 		2. Trans. Date 2A. Deemed Execution Date, if any 3. Trans. Code
(Instr. 8) 		4. Securities Acquired (A) or Disposed of (D)
(Instr. 3, 4 and 5) 		5. Amount of Securities Beneficially Owned Following Reported Transaction(s)
(Instr. 3 and 4) 		6. Ownership Form: Direct (D) or Indirect (I) (Instr. 4) 7. Nature of Indirect Beneficial Ownership (Instr. 4)
Code V Amount (A) or (D) Price
Common Stock   11/7/2011     D    184589   D $10.5   (1) 0   D    
Common Stock   11/7/2011     D    23427   D $10.5   (1) 0   I   By Trust   (2)
Common Stock   11/7/2011     D    14746   D $10.5   (1) 0   I   By Trust   (3)

Table II - Derivative Securities Beneficially Owned ( e.g. , puts, calls, warrants, options, convertible securities)
1. Title of Derivate Security
(Instr. 3) 		2. Conversion or Exercise Price of Derivative Security 3. Trans. Date 3A. Deemed Execution Date, if any 4. Trans. Code
(Instr. 8) 		5. Number of Derivative Securities Acquired (A) or Disposed of (D)
(Instr. 3, 4 and 5) 		6. Date Exercisable and Expiration Date 7. Title and Amount of Securities Underlying Derivative Security
(Instr. 3 and 4) 		8. Price of Derivative Security
(Instr. 5) 		9. Number of derivative Securities Beneficially Owned Following Reported Transaction(s) (Instr. 4) 10. Ownership Form of Derivative Security: Direct (D) or Indirect (I) (Instr. 4) 11. Nature of Indirect Beneficial Ownership (Instr. 4)
Code V (A) (D) Date Exercisable Expiration Date Title Amount or Number of Shares
Option (Right to Buy)   $4.25   11/7/2011     D         25000      (4) 8/9/2016   Common Stock   25000     (4) 0   D    
Option (Right to Buy)   $4.25   11/7/2011     D         11731      (5) 6/5/2017   Common Stock   11731     (5) 0   D    
Option (Right to Buy)   $3.43   11/7/2011     D         15790      (6) 6/3/2018   Common Stock   15790     (6) 0   D    
Option (Right to Buy)   $1.52   11/7/2011     D         18924      (7) 6/2/2019   Common Stock   18924     (7) 0   D    
Option (Right to Buy)   $4   11/7/2011     D         7030      (8) 6/2/2020   Common Stock   7030     (8) 0   D    
Option (Right to Buy)   $7.2   11/7/2011     D         3878      (9) 6/2/2021   Common Stock   3878     (9) 0   D    
Restricted Stock Unit     (10) 11/7/2011     D         2430      (11)   (12) Common Stock   2430     (11) 0   D    

Explanation of Responses:
( 1)  Shares were disposed of pursuant to the terms of the merger agreement (the "Merger Agreement") between the Issuer, PerkinElmer, Inc. and PerkinElmer Hopkinton Co. in exchange for the right to receive $10.50 per share in cash.
( 2)  Holdings in TTEE David W. Carter TR, The Survivor's Trustor's Share, U/A/D/, of which Mr. Carter is a trustee.
( 3)  Holdings in the Carter's descendents Trust, of which Mr. Carter is a trustee.
( 4)  This option, which was fully vested on 08/10/2011, was cancelled pursuant to the Merger Agreement in exchange for a cash payment for each share underlying the option equal to $6.25 per share, representing the difference between the merger consideration of $10.50 per share and the exercise price of the option.
( 5)  This option, which was fully vested on 06/06/2008, was cancelled pursuant to the Merger Agreement in exchange for a cash payment for each share underlying the option equal to $6.25 per share, representing the difference between the merger consideration of $10.50 per share and the exercise price of the option.
( 6)  This option, which was fully vested on 06/04/2009, was cancelled pursuant to the Merger Agreement in exchange for a cash payment for each share underlying the option equal to $7.07 per share, representing the difference between the merger consideration of $10.50 per share and the exercise price of the option.
( 7)  This option, which was fully vested on 06/03/2010, was cancelled pursuant to the Merger Agreement in exchange for a cash payment for each share underlying the option equal to $8.98 per share, representing the difference between the merger consideration of $10.50 per share and the exercise price of the option.
( 8)  This option, which was fully vested on 06/03/2011, was cancelled pursuant to the Merger Agreement in exchange for a cash payment for each share underlying the option equal to $6.50 per share, representing the difference between the merger consideration of $10.50 per share and the exercise price of the option.
( 9)  This option, which provided for vesting as to 25% of the underlying shares on the first anniversary of the grant date and as to an additional 1/48 of the shares monthly thereafter until the fourth anniversary of the grant date, became fully vested and cancelled as of the effective time of the merger pursuant to the Merger Agreement in exchange for a cash payment for each share underlying the option equal to $3.30 per share, representing the difference between the merger consideration of $10.50 per share and the exercise price of the option.
( 10)  Each restricted stock unit represents a contingent right to receive on share of Issuer common stock.
( 11)  These restricted stock units, which provided for one-year vesting from the date of grant, became fully vested and cancelled as of the effective time of the merger pursuant to the Merger Agreement in exchange for a cash payment equal to $10.50 per restricted stock unit.
( 12)  These restricted stock units do not have an expiration date.

Reporting Owners
Reporting Owner Name / Address
Relationships
Director 10% Owner Officer Other
CARTER DAVID WARREN
68 ELM STREET
HOPKINTON, MA 01748 		X



Signatures
/s/ Stephen E. Creager Attorney-In-Fact 11/7/2011
** Signature of Reporting Person Date


Reminder: Report on a separate line for each class of securities beneficially owned directly or indirectly.
* If the form is filed by more than one reporting person, see Instruction 4(b)(v).
** Intentional misstatements or omissions of facts constitute Federal Criminal Violations. See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a).
Note: File three copies of this Form, one of which must be manually signed. If space is insufficient, see Instruction 6 for procedure.
Persons who respond to the collection of information contained in this form are not required to respond unless the form displays a currently valid OMB control number.
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