XSI American Caresource Holdings

American CareSource Holdings, Inc. (AMEX: XSI) announced today that its Chief Executive Officer, David S. Boone, will present at the Fourth Annual Noble Financial Equity Conference at 3:00 p.m. PDT on August 18, 2008 at the Loews Lake Las Vegas Resort, Nevada.

Mr. Boone will give a 23-minute presentation regarding American CareSource's market positioning, financial performance, and strategic direction. A live webcast may be accessed through the Company's website at www.anci-care.com under "News & Events." The webcast will be archived for 30 days.

About American CareSource Holdings, Inc.

American CareSource Holdings, the first national, publicly traded ancillary care network services company offers a comprehensive national network of approximately 2,500 ancillary service providers at over 25,000 sites. The Company's ancillary network and management provides a complete outsourced solution for a wide variety of healthcare payors and plan sponsors including self-insured employers, indemnity insurers, PPOs, HMOs, third party administrators and both federal and local governments. For additional information, please visit www.anci-care.com.

Contact: Steven J. Armond Chief Financial Officer American CareSource Holdings, Inc. Tel: 972-308-6847