UNITED STATES
SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
FORM 15
CERTIFICATION AND NOTICE OF TERMINATION OF REGISTRATION UNDER SECTION 12(g) OF THE SECURITIES EXCHANGE ACT OF 1934 OR SUSPENSION OF DUTY TO FILE REPORTS UNDER SECTIONS 13 AND 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934.
Commission File Number: 001-33465
SIRTRIS PHARMACEUTICALS, INC.
(Exact name of registrant as specified in its charter)
200 Technology Square
Cambridge, MA 02139
(617) 252-6920
(Address, including zip code, and telephone number, including area code, of registrant’s principal executive offices)
Common Stock, par value $0.001 per share
(Title of each class of securities covered by this Form)
None
(Titles of all other classes of securities for which a duty to file reports under Section 13(a) or 15(d) remains)
Please place an X in the box(es) to designate the appropriate rule provision(s) relied upon to terminate or suspend the duty to file reports:
                 
 
  Rule 12g-4(a)(l)(i)   þ   Rule 12h-3(b)(l)(i)   þ
 
  Rule 12g-4(a)(l)(ii)   o   Rule 12h-3(b)(1)(ii)   o
 
  Rule 12g-4(a)(2)(i)   o   Rule 12h-3(b)(2)(i)   o
 
  Rule 12g-4(a)(2)(ii)   o   Rule 12h-3(b)(2)(ii)   o
 
          Rule 15d-6   o
Approximate number of holders of record as of the certification or notice date:
Common Stock, par value $0.001 per share — 1 holder
Pursuant to the requirements of the Securities Exchange Act of 1934, Sirtris Pharmaceuticals, Inc. has caused this Certification and Notice to be signed on its behalf by the undersigned duly authorized person.
Date: June 5, 2008
             
    SIRTRIS PHARMACEUTICALS, INC.
 
           
    By:   /s/ Christoph Westphal
         
 
      Name:   Christoph Westphal
 
      Title:   President, Chief Executive Officer and Vice Chairman
 
 

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