CUSIP No. 231269200
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Page 1 of 6
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UNITED STATES
SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
SCHEDULE 13G
Under the Securities Exchange Act of
1934
Curis, Inc.
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(Name of Issuer)
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Common Stock, Par Value $0.01 per share
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(Title of Class of Securities)
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231269200
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(CUSIP Number)
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December 31, 2020
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(Date of Event Which Requires Filing of this Statement)
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Check the appropriate box to designate the rule pursuant to
which this Schedule is filed:
x Rule
13d-1(b)
o Rule
13d-1(c)
o Rule
13d-1(d)
*The remainder of this cover page shall
be filled out for a reporting person’s initial filing on this form with respect to the subject class of securities, and for
any subsequent amendment containing information which would alter the disclosures provided in a prior cover page.
The information required in the remainder
of this cover page shall not be deemed to be “filed” for the purpose of Section 18 of the Securities Exchange Act of
1934 (“Act”) or otherwise subject to the liabilities of that section of the Act but shall be subject to all other provisions
of the Act (however, see the Notes).
CUSIP No. 231269200
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Page 2 of 6
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1.
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Names of Reporting Person
I.R.S. Identification Nos. of Above Persons (entities only)
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Sio Capital Management, LLC
20-4586565
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2.
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Check the Appropriate Box
if a Member of a Group
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(a) ¨
(b) ¨
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3.
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SEC Use Only
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4.
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Citizenship or Place
of Organization
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Delaware
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Number of Shares Beneficially
Owned by Each Reporting
Person With1
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5.
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Sole Voting Power
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-0-
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6.
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Shared Voting Power
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4,756,438
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7.
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Sole Dispositive Power
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-0-
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8.
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Shared Dispositive Power
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4,756,438
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9.
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Aggregate Amount Beneficially Owned by Each
Reporting Person
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4,756,438
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10.
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Check Box if the Aggregate Amount in Row (9)
Excludes Certain Shares
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¨
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11.
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Percent of Class Represented by Amount in
Row (9)
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5.78%2
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12.
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Type of Reporting Person
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IA
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1
As of December 31, 2020, Sio Capital Management, LLC beneficially owned 4,756,438 shares of Common Stock with shared voting power
and shared dispositive power. The ownership information reported in this Schedule 13G is as of December 31, 2020.
2
Based on 82,305,059 shares of common stock outstanding as reported in the Company's Prospectus filed pursuant to Rule 424(b)(5)
with the Securities and Exchange Commission on December 10, 2020, after giving effect to the completion of the offering as described
therein.
CUSIP No. 231269200
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Page 3 of 6
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Schedule 13G
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Item 1(a).
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Name of Issuer:
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Curis, Inc.
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Item 1(b).
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Address of Issuer’s Principal Executive Offices:
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128 Spring Street, Building C - Suite 500,
Lexington, Massachusetts 02421
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Item 2(a).
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Name of Persons Filing:
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This Statement is filed on behalf
of Sio Capital Management, LLC (the “Reporting Person” or “Sio”)
Sio is a registered investment
adviser to certain affiliated funds that directly hold the shares of Common Stock to which this statement relates for the benefit
of their respective investors, and in such capacity Sio has voting and dispositive power over such shares.
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Item 2(b).
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Address of Principal Business Office:
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600 Third Avenue, 2nd Floor
New York, New York 10016
Sio is a Delaware limited liability company.
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Item 2(d).
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Title of Class of Securities:
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Common Stock, Par Value $0.01 per share
231269200
CUSIP No. 231269200
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Item 3. If this statement is filed pursuant to §§
240.13d-1(b) or 240.13d-2(b) or (c), check whether the person filing is a:
(a)
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¨
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Broker or dealer registered under section 15 of the Act (15 U.S.C. 78o).
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(b)
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¨
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Bank as defined in section 3(a)(6) of the Act (15 U.S.C. 73c).
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(c)
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¨
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Insurance company as defined in section 3(a)(19) of the Act (15 U.S.C.78c).
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(d)
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¨
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Investment company registered under section 8 of the Investment Company Act of 1940 (15 U.S.C. 80a-8).
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(e)
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x
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An investment adviser in accordance with §13d-1(b)(1)(ii)(E).
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(f)
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¨
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An employee benefit plan or endowment fund in accordance with §240.13d-1(b)(1)(ii)(F).
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(g)
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¨
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A parent holding company or control person in accordance with §240.13d-1(b)(1)(ii)(G).
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(h)
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¨
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A savings association as defined in Section 3(b) of the Federal Deposit Insurance Act (12 U.S.C. 1813).
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(i)
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¨
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A church plan that is excluded from the definition of an investment company under section 3(c)(14) of the Investment Company Act of 1940 (15 U.S.C. 80a-3).
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(j)
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¨
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Group, in accordance with §240.13d-1(b)(1)(ii)(J).
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¨
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If this statement is filed pursuant to §240.13d-1(c), check this box.
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Item 4. Ownership.
(a) through (c):
The information set forth in Items 5 through
9 and 11 of the cover pages to this Schedule 13G is incorporated herein by reference.3
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Item 5.
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Ownership of Five Percent or Less of a Class.
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Not Applicable.
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Item 6.
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Ownership of More than Five Percent on Behalf of Another Person.
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Various advisory clients of the
Reporting Person have the right to receive or the power to direct the receipt of dividends from, or the proceeds from the sale
of, the Common Stock of Curis, Inc. in their accounts with the Reporting Person. No such person has such interest relating to more
than 5% of the outstanding shares of Common Stock of Curis, Inc.
3
Sio and Sio GP, LLC (the “GP”) act as investment advisor and general partner, respectively, to various clients that
are the record owners of the Common Stock reported on this Schedule 13G. Because Sio’s investment discretion with respect
to such clients is subject to oversight by the GP, the GP may be deemed to be the beneficial owner of the Common Stock of the Issuer
owned by such clients. In addition, both Sio and the GP are controlled by Michael Castor. As such, he may be deemed to control
the voting and dispositive decisions with respect to, and therefore be the beneficial owner of, the shares of Common Stock reported
on this Schedule 13G. Neither the filing of this Schedule 13G nor any of its contents shall be deemed to constitute an admission
by the GP or Michael Castor that such person is the beneficial owner of any of the equity securities referred to herein for purposes
of Section 13(d) of the Exchange Act, or for any other purpose, and such beneficial ownership is expressly disclaimed.
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Item 7.
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Identification and Classification of the Subsidiary Which Acquired the Security Being Reported By the Parent Holding Company.
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Not Applicable.
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Item 8.
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Identification and Classification of Members of the Group.
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Not Applicable.
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Item 9.
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Notice of Dissolution of a Group.
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Not Applicable.
By signing below I certify that, to the
best of my knowledge and belief, the securities referred to herein were acquired and are held in the ordinary course of business
and were not acquired and are not held for the purpose of or with the effect of changing or influencing the control of the Issuer
and were not acquired and are not held in connection with or as a participant in any transaction having that purpose or effect.
CUSIP No. 231269200
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SIGNATURE
After reasonable inquiry and to the best of my knowledge and
belief, I certify that the information set forth in this statement is true, complete and correct.
Dated: February 12, 2021
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SIO CAPITAL MANAGEMENT, LLC
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By:
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Name: Judah Drillick
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Title: Chief Executive Officer
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