By Cassandra Sweet 

Twelve people were injured and six were being treated for critical or serious injuries at a Fresno, Calif., hospital over the weekend after a PG&E Corp. natural gas pipeline ruptured and ignited a fire.

The underground high-pressure natural-gas transmission pipeline ruptured Friday afternoon after a Fresno County employee was operating heavy earth-moving equipment near it, according to a county Sheriff's Department spokesman and PG&E.

In addition to the six people hospitalized with critical or serious injuries in Fresno, six others were treated at two different hospitals. At least four of them have been released, officials said.

Workers at the site likely struck the pipeline while digging, allowing gas to escape which ignited a fire, said Nick Stimmel, a PG&E spokesman. Utility workers arrived at the scene and shut off the flow of gas within 45 minutes of being notified of the pipeline rupture, the utility said.

"Our primary concern is always the safety of the public and our employees," Mr. Stimmel said, adding the utility is cooperating with an investigation being conducted by California's Public Utilities Commission.

Six people were being treated Sunday at Community Regional Medical Center in Fresno, a hospital spokeswoman said. Four were in critical condition, with burns, and were being treated in the intensive care unit; two others were listed as being in serious condition.

Four other people injured in Friday's blast were taken to nearby St. Agnes Medical Center. All four were treated and released on Friday, a hospital spokeswoman said.

Two other people injured in the blaze were taken to Madera Community Medical Center. A nurse reached at the hospital Sunday declined to comment on their condition.

The accident occurred at a gun firing range owned and operated by the Fresno County Sheriff's Foundation, a nonprofit organization that offers community activities such as summer day camps for school children, according to the foundation's website.

The county employee who was operating a front-end loader at the site was among those injured in the blast, according to the Sheriff's Department. The 11 other injured were inmates at the Fresno County Jail, who were performing cleanup duties at the firing range, according to the department.

PG&E is awaiting permission from state regulators to replace the damaged section of pipeline and make other repairs, according to the utility.

Write to Cassandra Sweet at cassandra.sweet@wsj.com

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