FORM 4
☐ Check this box if no longer subject to Section 16. Form 4 or Form 5 obligations may continue. See Instruction 1(b).         
 UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549

STATEMENT OF CHANGES IN BENEFICIAL OWNERSHIP OF SECURITIES
                                                                                  
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Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934 or Section 30(h) of the Investment Company Act of 1940
                      

1. Name and Address of Reporting Person *

Lagano Roxanne		 2. Issuer Name and Ticker or Trading Symbol

Zoetis Inc. [ ZTS ] 		5. Relationship of Reporting Person(s) to Issuer (Check all applicable)

_____ Director                    _____ 10% Owner
__X__ Officer (give title below)    _____ Other (specify below)
Executive Vice President
(Last)          (First)          (Middle)

C/O ZOETIS INC., 10 SYLVAN WAY		 3. Date of Earliest Transaction (MM/DD/YYYY)

4/18/2023
(Street)

PARSIPPANY, NJ 07054		 4. If Amendment, Date Original Filed (MM/DD/YYYY)

 
 6. Individual or Joint/Group Filing (Check Applicable Line)

_X _ Form filed by One Reporting Person
___ Form filed by More than One Reporting Person
(City)        (State)        (Zip)
Rule 10b5-1(c) Transaction Indication
☒ Check this box to indicate that a transaction was made pursuant to a contract, instruction or written plan that is intended to satisfy the affirmative defense conditions of Rule 10b5-1(c). See Instruction 10.

Table I - Non-Derivative Securities Acquired, Disposed of, or Beneficially Owned
1.Title of Security
(Instr. 3) 		2. Trans. Date 2A. Deemed Execution Date, if any 3. Trans. Code
(Instr. 8) 		4. Securities Acquired (A) or Disposed of (D)
(Instr. 3, 4 and 5) 		5. Amount of Securities Beneficially Owned Following Reported Transaction(s)
(Instr. 3 and 4) 		6. Ownership Form: Direct (D) or Indirect (I) (Instr. 4) 7. Nature of Indirect Beneficial Ownership (Instr. 4)
Code V Amount (A) or (D) Price
Common Stock 4/18/2023  M(1)  2328 A$73.24 28685 D  
Common Stock 4/18/2023  M(1)  2010 A$87.51 30695 D  
Common Stock 4/18/2023  S  4338 D$175.94 (2)26357 D  
Common Stock         793.2659 (3)I 401(k) 

Table II - Derivative Securities Beneficially Owned (e.g., puts, calls, warrants, options, convertible securities)
1. Title of Derivate Security
(Instr. 3)		2. Conversion or Exercise Price of Derivative Security3. Trans. Date3A. Deemed Execution Date, if any4. Trans. Code
(Instr. 8)		5. Number of Derivative Securities Acquired (A) or Disposed of (D)
(Instr. 3, 4 and 5)		6. Date Exercisable and Expiration Date7. Title and Amount of Securities Underlying Derivative Security
(Instr. 3 and 4)		8. Price of Derivative Security
(Instr. 5)		9. Number of derivative Securities Beneficially Owned Following Reported Transaction(s) (Instr. 4)10. Ownership Form of Derivative Security: Direct (D) or Indirect (I) (Instr. 4)11. Nature of Indirect Beneficial Ownership (Instr. 4)
CodeV(A)(D)Date ExercisableExpiration DateTitleAmount or Number of Shares
Stock Option (4) (5)4/18/2023  M     2328   (6) (7)Common Stock 2328.0 $0 22231 (8)D  
Stock Option (4) (9)4/18/2023  M     2010   (6) (7)Common Stock 2010.0 $0 20221 (10)D  
Stock Option (11)$162.07            (12) (7)Common Stock 6542.0  6542 D  
Explanation of Responses:
(1) The transactions reported in this Form 4 were effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on February 25, 2022.
(2) The Price reported in Table I, Column 4 is the price at which these shares were sold in multiple transactions.
(3) Represents the common stock equivalents held in the Zoetis Inc. Savings Plan, a 401(k) plan, as of March 31, 2023.
(4) Stock options (right to buy Zoetis Inc. common stock) granted pursuant to the Zoetis Inc. 2013 Equity and Incentive Plan.
(5) 2,328 options granted February 13, 2018 at an exercise price of $73.24 per option.
(6) Each option vests on the third anniversary of the date of grant.
(7) Each option expires on the tenth anniversary of the date of grant.
(8) 2,010 options granted February 12, 2019 at an exercise price of $87.51 per option; 7,738 options granted February 11, 2020 at an exercise price of $144.03 per option; 7,106 options granted February 10, 2021 at an exercise price of $160.62 per option; and 5,377 options granted February 8, 2022 at an exercise price of $201.30 per option.
(9) 2,010 options granted on February 12, 2019 at an exercise price of $87.51 per option.
(10) 7,738 options granted February 11, 2020 at an exercise price of $144.03 per option; 7,106 options granted February 10, 2021 at an exercise price of $160.62 per option; and 5,377 options granted February 8, 2022 at an exercise price of $201.30 per option.
(11) Stock options (right to buy Zoetis Inc. common stock) granted pursuant to the Zoetis Inc. Amended and Restated 2013 Equity and Incentive Plan.
(12) One-third of each option will vest on the first, second and third anniversaries of the date of grant.

Reporting Owners
Reporting Owner Name / Address
Relationships
Director10% OwnerOfficerOther
Lagano Roxanne
C/O ZOETIS INC.
10 SYLVAN WAY
PARSIPPANY, NJ 07054

Executive Vice President
Signatures
/s/ Lauren Luptak, as Attorney-in-Fact4/19/2023
**Signature of Reporting PersonDate
Reminder: Report on a separate line for each class of securities beneficially owned directly or indirectly.
*If the form is filed by more than one reporting person, see Instruction 4(b)(v).
**Intentional misstatements or omissions of facts constitute Federal Criminal Violations. See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a).
Note:File three copies of this Form, one of which must be manually signed. If space is insufficient, see Instruction 6 for procedure.
Persons who respond to the collection of information contained in this form are not required to respond unless the form displays a currently valid OMB control number.
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