| Explanation of Responses: |
| (1) | Reflects disposition of Issuer common stock with the consummation of the transactions contemplated by the Agreement and Plan of Merger (the
"Merger Agreement"), dated as of July 20, 2022, by and among Issuer, Amazon.com, Inc. ("Parent") and Negroni Merger Sub, Inc., a wholly
owned subsidiary of Parent ("Merger Sub"), including the consummation of the merger (the "Merger") between Issuer and Merger Sub on
February 22, 2023. Pursuant to the Merger Agreement, as of the effective time of the Merger (the "Effective Time"), each share of Issuer
common stock, par value $0.001 per share ("Shares") issued and outstanding immediately prior to the Effective Time was converted
automatically into the right to receive $18.00 in cash, without interest (the "Merger Consideration"). |
| (2) | Pursuant to the Merger Agreement, at the Effective Time, each outstanding option ("Option") to purchase Shares granted under any of the
Issuer's 2007 Equity Incentive Plan, 2017 Equity Incentive Plan, 2020 Equity Incentive Plan and the Iora Third Amended and Restated 2011
Equity Incentive Plan (collective, the "Issuer Stock Plans") or portion thereof that was vested or became vested as of the Effective Time, and
had an exercise price per Share that is less than the Merger Consideration, was canceled and converted into the right to receive an amount in
cash, without interest, equal to the product of (i) the amount by which the Merger Consideration exceeds the applicable exercise price per Share
of such Option and (ii) the aggregate number of Shares issuable upon exercise of such Option or portion thereof, subject to any required
withholding of taxes. |
| (3) | The shares subject to the option are fully vested and immediately exercisable. |
| (4) | Pursuant to the Merger Agreement, at the Effective Time, each outstanding Option that was unvested and that had an exercise price per Share that was less than the Merger Consideration was, by virtue of the Merger, converted into the right to receive an amount in cash equal to the
product of (i) the amount by which the Merger Consideration exceeds the exercise price per Share of such Option and (ii) the aggregate number
of Shares subject to such unvested Option or portion thereof as of immediately prior to the Effective Time (the "Unvested Option Payment"),
provided that such Unvested Option Payment (x) shall be subject to the same vesting and forfeiture provisions as were applicable to such
unvested Option immediately prior to the Effective Time, (y) shall vest in installments over the remainder of the vesting schedule of such Option
based on the same percentage of the Option that would have vested on each applicable vesting date, subject to any required withholding of
taxes. |
| (5) | The shares subject to the option vest as follows: 20% of the shares subject to the option vest on the first anniversary of the vesting
commencement date; and 1/60th of the shares subject to the option vest monthly thereafter over the following four years, subject to reporting
person's continuous service as of each such date. |
| (6) | The shares subject to the option vest as follows: 1/48th of the shares subject to the option vest monthly over four years commencing on the
vesting commencement date, subject to reporting person's continuous service as of each such date. |
| (7) | Pursuant to the Merger Agreement, at the Effective Time, each Option, whether vested or unvested, that has an exercise price per Share that is
greater than the Merger Consideration was canceled without the payment of consideration. |
| (8) | The shares subject to the option vest as follows: options vest monthly over three years, with 25% of the shares subject to the option vesting on
each of the first and second anniversaries of the vesting commencement date and 50% of the shares subject to the option vesting on the third
anniversary of the vesting commencement date, subject to the reporting person's continuous service as of each such date. |
| (9) | Each restricted stock unit ("RSU") represents a contingent right to receive one share of the issuer's common stock. RSUs convert into the
issuer's common stock on a one-for-one basis. |
| (10) | Pursuant to the Merger Agreement, at the Effective Time, each outstanding RSU granted under any Issuer Stock Plan that was unvested as of
the Effective Time, by virtue of the Merger, was converted into the right to receive an amount in cash equal to the product of (i) the Merger
Consideration and (ii) the aggregate number of Shares subject to such unvested RSU as of immediately prior to the Effective Time (the
"Unvested RSU Payment"), provided that such Unvested RSU Payment (x) shall be subject to the same vesting and forfeiture provisions as
were applicable to such unvested RSU immediately prior to the Effective Time, (y) shall vest in installments over the remainder of the vesting
schedule of such RSU based on the same percentage of the RSU that would have vested on each applicable vesting date and (z) shall be
subject to forfeiture on the same terms and conditions as were applicable to such RSU, subject to any required withholding of taxes. |
| (11) | The RSUs vest in equal annual installments over four years on the anniversary of the vesting commencement date, subject to the reporting
person's continuous service as of each such date. |
| (12) | The RSUs vest annually over three years, with 25% of the RSUs vesting on each of the first and second anniversaries of the vesting
commencement date and 50% of the RSUs vesting on the third anniversary of the vesting commencement date, subject to the reporting
person's continuous service as of each such date. |
| (13) | The RSUs vest annually over four years, with 50% of the RSUs units vesting on the first anniversary of the grant date; 20% vesting on the
second anniversary of the grant date; and 15% vesting on each of the third and fourth anniversaries of the grant date, subject to reporting
person's continuous service as of each such date. |