FORM 4
[ X ] Check this box if no longer subject to Section 16. Form 4 or Form 5 obligations may continue. See Instruction 1(b).         
UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549

STATEMENT OF CHANGES IN BENEFICIAL OWNERSHIP OF SECURITIES
                                                                                  
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Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934, Section 17(a) of the Public
Utility Holding Company Act of 1935 or Section 30(f) of the Investment Company Act of 1940
                      

1. Name and Address of Reporting Person *

Fanucci Marsha
2. Issuer Name and Ticker or Trading Symbol

MILLENNIUM PHARMACEUTICALS INC [ MLNM ]
5. Relationship of Reporting Person(s) to Issuer (Check all applicable)

_____ Director                      _____ 10% Owner
__ X __ Officer (give title below)      _____ Other (specify below)
SVP, Chief Financial Officer
(Last)          (First)          (Middle)

MILLENNIUM PHARMACEUTICALS, INC., 40 LANDSDOWNE STREET
3. Date of Earliest Transaction (MM/DD/YYYY)

5/14/2008
(Street)

CAMBRIDGE, MA 02139
(City)        (State)        (Zip)
4. If Amendment, Date Original Filed (MM/DD/YYYY)

 
6. Individual or Joint/Group Filing (Check Applicable Line)

_ X _ Form filed by One Reporting Person
___ Form filed by More than One Reporting Person

Table I - Non-Derivative Securities Acquired, Disposed of, or Beneficially Owned
1.Title of Security
(Instr. 3)
2. Trans. Date 2A. Deemed Execution Date, if any 3. Trans. Code
(Instr. 8)
4. Securities Acquired (A) or Disposed of (D)
(Instr. 3, 4 and 5)
5. Amount of Securities Beneficially Owned Following Reported Transaction(s)
(Instr. 3 and 4)
6. Ownership Form: Direct (D) or Indirect (I) (Instr. 4) 7. Nature of Indirect Beneficial Ownership (Instr. 4)
Code V Amount (A) or (D) Price
Common Stock   5/14/2008     D    109514   (1) D $25.00   0   D    

Table II - Derivative Securities Beneficially Owned ( e.g. , puts, calls, warrants, options, convertible securities)
1. Title of Derivate Security
(Instr. 3)
2. Conversion or Exercise Price of Derivative Security 3. Trans. Date 3A. Deemed Execution Date, if any 4. Trans. Code
(Instr. 8)
5. Number of Derivative Securities Acquired (A) or Disposed of (D)
(Instr. 3, 4 and 5)
6. Date Exercisable and Expiration Date 7. Title and Amount of Securities Underlying Derivative Security
(Instr. 3 and 4)
8. Price of Derivative Security
(Instr. 5)
9. Number of derivative Securities Beneficially Owned Following Reported Transaction(s) (Instr. 4) 10. Ownership Form of Derivative Security: Direct (D) or Indirect (I) (Instr. 4) 11. Nature of Indirect Beneficial Ownership (Instr. 4)
Code V (A) (D) Date Exercisable Expiration Date Title Amount or Number of Shares
Employee stock option (right to buy)   $16.13   5/14/2008           6019      (2) 9/26/2011   Common Stock   6019   $0   0   D    
Employee stock option (right to buy)   $19.49   5/14/2008           13164      (2) 2/27/2012   Common Stock   13164   $0   0   D    
Employee stock option (right to buy)   $22.04   5/14/2008           13164      (2) 3/27/2012   Common Stock   13164   $0   0   D    
Employee stock option (right to buy)   $18.42   5/14/2008           6855      (2) 4/26/2012   Common Stock   6855   $0   0   D    
Employee stock option (right to buy)   $7.99   5/14/2008           2988      (2) 10/17/2012   Common Stock   2988   $0   0   D    
Employee stock option (right to buy)   $8.27   5/14/2008           2988      (2) 11/15/2012   Common Stock   2988   $0   0   D    
Employee stock option (right to buy)   $9.35   5/14/2008           2987      (2) 12/17/2012   Common Stock   2987   $0   0   D    
Employee stock option (right to buy)   $6.88   5/14/2008           19271      (2) 2/26/2013   Common Stock   19271   $0   0   D    
Employee stock option (right to buy)   $12.57   5/14/2008           7119      (2) 7/31/2013   Common Stock   7119   $0   0   D    
Employee stock option (right to buy)   $13.91   5/14/2008           7118      (2) 8/29/2013   Common Stock   7118   $0   0   D    
Employee stock option (right to buy)   $14.68   5/14/2008           19272      (2) 9/2/2013   Common Stock   19272   $0   0   D    
Employee stock option (right to buy)   $15.45   5/14/2008           7118      (2) 9/30/2013   Common Stock   7118   $0   0   D    
Employee stock option (right to buy)   $15.92   5/14/2008           7813      (2) 10/31/2013   Common Stock   7813   $0   0   D    
Employee stock option (right to buy)   $15.83   5/14/2008           7812      (2) 11/28/2013   Common Stock   7812   $0   0   D    
Employee stock option (right to buy)   $18.65   5/14/2008           7812      (2) 12/31/2013   Common Stock   7812   $0   0   D    
Employee stock option (right to buy)   $17.77   5/14/2008           37500      (2) 2/25/2014   Common Stock   37500   $0   0   D    
Employee stock option (right to buy)   $11.15   5/14/2008           25000      (2) 7/28/2014   Common Stock   25000   $0   0   D    
Employee stock option (right to buy)   $11.89   5/14/2008           25000      (2) 8/31/2014   Common Stock   25000   $0   0   D    
Employee stock option (right to buy)   $12.09   5/14/2008           37500      (2) 9/1/2014   Common Stock   37500   $0   0   D    
Employee stock option (right to buy)   $13.36   5/14/2008           125000      (2) 9/23/2014   Common Stock   125000   $0   0   D    
Employee stock option (right to buy)   $13.67   5/14/2008           25000      (2) 9/30/2014   Common Stock   25000   $0   0   D    
Employee stock option (right to buy)   $8.41   5/14/2008           212500      (2) 3/3/2015   Common Stock   212500   $0   0   D    
Employee stock option (right to buy)   $10.84   5/14/2008           45000      (2) 2/27/2017   Common Stock   45000   $0   0   D    
Employee stock option (right to buy)   $13.90   5/14/2008           68395      (2) 2/14/2008   Common Stock   68395   $0   0   D    

Explanation of Responses:
( 1)  Reflects shares of restricted stock that were exchanged for a cash payment of $25.00 per share in connection with the merger (the "Merger") of Mahogany Acquisition Corp. with and into Millennium Pharmaceuticals, Inc.
( 2)  This option was cancelled in the Merger in exchange for a cash payment per underlying share equal to the difference between the exercise price and $25.00.

Reporting Owners
Reporting Owner Name / Address
Relationships
Director 10% Owner Officer Other
Fanucci Marsha
MILLENNIUM PHARMACEUTICALS, INC.
40 LANDSDOWNE STREET
CAMBRIDGE, MA 02139


SVP, Chief Financial Officer

Signatures
Joel S. Goldberg, Attorney-In-Fact 5/15/2008
** Signature of Reporting Person Date


Reminder: Report on a separate line for each class of securities beneficially owned directly or indirectly.
* If the form is filed by more than one reporting person, see Instruction 4(b)(v).
** Intentional misstatements or omissions of facts constitute Federal Criminal Violations. See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a).
Note: File three copies of this Form, one of which must be manually signed. If space is insufficient, see Instruction 6 for procedure.
Persons who respond to the collection of information contained in this form are not required to respond unless the form displays a currently valid OMB control number.
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