CLOSURE Medical Announces Date of Its Fourth Quarter and Year-End 2004 Results Release and Conference Call RALEIGH, N.C., Feb. 18 /PRNewswire-FirstCall/ -- CLOSURE Medical Corporation (NASDAQ:CLSR), a global leader in biomaterial-based medical devices, announced plans to release its fourth quarter 2004 results on February 23, 2005, at 4:05 p.m. EST (Eastern); at 4:30 p.m. EST, management will host a conference call, which will be broadcast live over the Internet. Those interested in listening to the live webcast may do so by going to the Company's website at http://www.closuremed.com/. Web participants are encouraged to go to the website at least 15 minutes prior to the start of the call to register, download, and install any necessary audio software. The online archive will be available within two hours following the live webcast and will continue for 30 days. About CLOSURE Medical Corporation CLOSURE Medical Corporation (NASDAQ:CLSR) is a global leader in the development and manufacture of innovative biomaterial-based medical devices that fulfill the needs of healthcare practitioners, patients and consumers. For additional information on CLOSURE Medical visit its website at http://www.closuremed.com/ or visit the "Clients" section of the Allen & Caron website at http://www.allencaron.com/. Contact: Allen & Caron Inc Joe Allen (investors) 212-691-8087 Len Hall (media) 949-474-4300 CLOSURE Medical Corp Benny Ward, CFO 919-876-7800 DATASOURCE: CLOSURE Medical Corporation CONTACT: investors, Joe Allen, +1-212-691-8087, , or media, Len Hall, +1-949-474-4300, , both of Allen & Caron Inc, for CLOSURE Medical Corporation, or Benny Ward, CFO of CLOSURE Medical Corporation, +1-919-876-7800 Web site: http://www.closuremed.com/ http://www.allencaron.com/

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