CHICAGO, Nov. 22, 2022 /PRNewswire/ -- According to Arizton's latest research report, the atopic dermatitis treatment market is expected to reach USD 11.34 billion by 2027. The most common type of eczema is atopic dermatitis. Increasing demand for biologics, the growing burden of allergic reactions, and the anticipated launch of emerging drugs are the major drivers in the market.

Atopic Dermatitis Treatment Market

With more than 150+ molecules in various stages of development, new vendors are expected to enter the market with novel mechanisms of action with better safety and efficacy profiles than the existing patented commercial drugs for treating atopic dermatitis. Promising late-stage medications with a range of mechanisms of action, including OX-40 antagonists, S1P receptor modulators, tyrosine kinase inhibitors, interleukin inhibitors, and PDE-4 inhibitors, are anticipated to hit the market soon.

Atopic dermatitis is children's most common skin disease, with prevalence steadily increasing from 8% to 12% in the last two decades. It is distinguished by a defect in the skin barrier that allows allergens and other irritants to enter the skin, resulting in an immune response and inflammation. This reaction causes a red, itchy rash that most commonly appears on the face, arms, and legs, which can cover large areas of the body. The inflammation causes severe pruritus (itching), resulting in damage from scratching or rubbing, perpetuating an 'itch-scratch' cycle. Pediatric patients with atopic dermatitis can suffer from sleep disturbances, behavioral problems, irritability, crying, and interference with normal childhood activities and social functioning. Adults with atopic dermatitis also frequently suffer from sleep disturbances, emotional impacts, and impaired social functioning.

Atopic Dermatitis Treatment Market Report Scope

Report Attributes

Details

Market Size 2021

USD 4.85 Billion

Market Size 2027

USD 11.34 Billion

CAGR (2022-2027)

15.2 %

Base year

2021

Forecast Year

2022-2027

Region Covered

North America, Europe, APAC, North America, Europe, APAC

Key Leading Countries

The US, China, Japan, France, Germany, the UK, Italy, and Spain

Market Segmentation

Drug Class, Gender Type, Age Group, Severity Type, and Geography

Market Dynamics

Increasing Demand for Biologics

Growing Burden of Allergic Reactions

Anticipated Launch of Emerging Drugs

Competitive Landscape

Company Overview and Product Offerings

Key Emerging Drugs in the Upcoming Years

Rocatinlimab, Roflumilast, Lebrikizumab, Tapinarof, Difelikefalin, Orismilast, and Tradipitant

Key Companies

LEO Pharma, Pfizer, Sanofi/Regeneron, Novartis, Incyte Corp, AbbVie, Eli Lilly and Company, Japan Tobacco Inc, Maruho Co., Ltd, Otsuka Holdings Co Ltd, Astellas Pharma Inc, Stiefel Laboratories, Arcutis Biotherapeutics, Kyowa Hakko Kirin, Vanda Pharmaceuticals, Dermavant Sciences, CARA Therapeutics, AstraZeneca Plc (AstraZeneca), UNION therapeutics,

Asana, Evelo Biosciences, BiomX, AOBiome Therapeutics, Inc., Amytrx, RAPT Therapeutics, Oneness Biotech, VYNE's Therapeutics, BenevolentAI Ltd, vTv Therapeutics Inc., Botanix Pharmaceuticals Ltd (BOT), selectION, Inc., Inmagene, and Novan, Inc.

Page number

230

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Key Insights

  • The United States accounted for more than 60% of the global atopic dermatitis therapeutics market. Due to the rise in the prevalence of atopic dermatitis, the presence of key players, the increase in healthcare affordability in the US, knowledge, and awareness amongst the people, and technological advancement are the major drivers in this region.
  • Topical corticosteroids accounted for a significant share of more than 81.23% of the global atopic dermatitis therapeutics due to their wide recommendation in the front-line setting. However, the other class of drugs is expected to be the fastest-growing segment during the forecast period.
  • Women accounted for a share of 51.03% in global atopic dermatitis. This is due to women being the more significant risk of atopic dermatitis in recent years.
  • Among the severity, mild form accounted for a significant share of 45.28% in the global atopic dermatitis therapeutics market. However, Moderate form is expected to be the fastest-growing segment during the forecast period.

Report Covers

  • Detailed overview of the atopic dermatitis treatment market, including disease definition, classification, diagnosis, and treatment pattern
  • Overview of the global trends of atopic dermatitis in the eight major markets (8MM)
  • Historical, current, and projected patient pool of atopic dermatitis in the eight major markets (8MM) for 2018 – 2027
  • In-depth market segment analysis, including products, treatment, and competitor analysis
  • Atopic dermatitis treatment market share of the market players, company profiles, product specifications, and competitive landscape
  • Comprehensive data on emerging trends, market drivers, growth opportunities, and restraints
  • Detailed overview of marketed drugs with key coverage of developmental activities, including sponsor name, approved indication, territory, collaborations, licensing, mergers and acquisitions, regulatory designations, and other product-related activities
  • Detailed overview of therapeutic pipeline activity and therapeutic assessment of the products by development stage, product type, route of administration, molecule type, and MOA type for Atopic Dermatitis across the complete product development cycle, including all clinical and non-clinical stages
  • Detailed overview of clinical trial activity and therapeutic assessment of the products by development stage, product type, route of administration, molecule type, and geography type for atopic dermatitis across all clinical stages
  • Coverage of dormant and discontinued pipeline projects, along with the reasons across the atopic dermatitis treatment market
  • Coverage of significant milestones (product approvals/launches timelines, clinical trial result publications, regulatory designations, licensing & collaborations, research & development progress of pipeline assets) in the atopic dermatitis space

Atopic Dermatitis: Clinical Trials Scenario

The clinical trial portfolio contains 153+ trials in various development phases. Most industry-sponsored drugs in active clinical development for atopic dermatitis are in the Phase II stage. The distribution of clinical trials across Phase I-IV indicates that most trials for atopic dermatitis have been in the mid-phase of development, with 47% of trials in Phase I/II & II and only 29% in Phase II/III-III.

Market Segmentation

Drug Class

  • Topical Steroids
  • Topical Calcineurin Inhibitors
  • Other Class of Drugs

Gender Type

  • Men
  • Women

Age Group

  • 18 years and Below
  • 19 years and Above

Severity Type

  • Moderate
  • Mild
  • Severe

Geography

  • North America
    • The U.S.
  • APAC
    • China
    • Japan
  • Europe
    • France
    • Germany
    • UK
    • Italy
    • Spain

Key Leading Vendors

  • LEO Pharma
  • Pfizer
  • Sanofi/Regeneron
  • Novartis
  • Incyte Corp
  • AbbVie
  • Eli Lilly and Company
  • Japan Tobacco Inc
  • Maruho Co., Ltd
  • Otsuka Holdings Co Ltd
  • Astellas Pharma Inc
  • Stiefel Laboratories
  • Arcutis Biotherapeutics
  • Kyowa Hakko Kirin
  • Vanda Pharmaceuticals
  • Dermavant Sciences
  • CARA Therapeutics
  • AstraZeneca Plc (AstraZeneca)
  • UNION therapeutics
  • Asana
  • Evelo Biosciences
  • BiomX
  • AOBiome Therapeutics, Inc.
  • Amytrx
  • RAPT Therapeutics
  • Oneness Biotech
  • VYNE's Therapeutics
  • BenevolentAI Ltd
  • vTv Therapeutics Inc.
  • Botanix Pharmaceuticals Ltd (BOT)
  • selectION, Inc.
  • Inmagene
  • Novan, Inc.

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Table of Content Offered in the Report

1. ATOPIC DERMATITIS OVERVIEW
1.1. Atopic Dermatitis Disease – An Overview

2. ATOPIC DERMATITIS EPIDEMIOLOGY & OVERVIEW
2.1. 8MM: Historic & Projected Volume of Incidence & Prevalence of Atopic Dermatitis
2.2. 8MM: Comparative Analysis of Incidence & Prevalence of Atopic Dermatitis
2.3. 8MM: Historic & Projected Volume of Incidence of Atopic Dermatitis cases by Severity Type
2.4. 8MM: Historic & Projected Volume of Incidence of Atopic Dermatitis cases by Age Group
2.5. 8MM: Historic & Projected Volume of Prevalence of Atopic Dermatitis cases by Severity Type
2.6. 8MM: Historic & Projected Volume of Prevalence of Atopic Dermatitis cases by Age Group
2.7. US: Historic & Projected Volume of Incidence & Prevalence of Atopic Dermatitis
2.8. US: Comparative Analysis of Incidence & Prevalence of Atopic Dermatitis
2.9. US: Historic & Projected Volume of Incidence of Atopic Dermatitis cases by Severity Type
2.10. US: Historic & Projected Volume of Incidence of Atopic Dermatitis cases by Age Group
2.11. US: Historic & Projected Volume of Prevalence of Atopic Dermatitis cases by Severity Type
2.12. US: Historic & Projected Volume of Prevalence of Atopic Dermatitis cases by Age Group
2.13. China: Historic & Projected Volume of Incidence & Prevalence of Atopic Dermatitis
2.14. China: Comparative Analysis of Incidence & Prevalence of Atopic Dermatitis
2.15. China: Historic & Projected Volume of Incidence of Atopic Dermatitis cases by Severity Type
2.16. China: Historic & Projected Volume of Incidence of Atopic Dermatitis cases by Age Group
2.17. China: Historic & Projected Volume of Prevalence of Atopic Dermatitis cases by Severity Type
2.18. China: Historic & Projected Volume of Prevalence of Atopic Dermatitis cases by Age Group
2.19. Japan: Historic & Projected Volume of Incidence & Prevalence of Atopic Dermatitis
2.20. Japan: Comparative Analysis of Incidence & Prevalence of Atopic Dermatitis
2.21. Japan: Historic & Projected Volume of Incidence of Atopic Dermatitis cases by Severity Type
2.22. Japan: Historic & Projected Volume of Incidence of Atopic Dermatitis cases by Age Group
2.23. Japan: Historic & Projected Volume of Prevalence of Atopic Dermatitis cases by Severity Type
2.24. Japan: Historic & Projected Volume of Prevalence of Atopic Dermatitis cases by Age Group
2.25. Germany: Historic & Projected Volume of Incidence & Prevalence of Atopic Dermatitis
2.26. Germany: Comparative Analysis of Incidence & Prevalence of Atopic Dermatitis
2.27. Germany: Historic & Projected Volume of Incidence of Atopic Dermatitis cases by Severity Type
2.28. Germany: Historic & Projected Volume of Incidence of Atopic Dermatitis cases by Age Group
2.29. Germany: Historic & Projected Volume of Prevalence of Atopic Dermatitis cases by Severity Type
2.30. Germany: Historic & Projected Volume of Prevalence of Atopic Dermatitis cases by Age Group
2.31. UK: Historic & Projected Volume of Incidence & Prevalence of Atopic Dermatitis
2.32. UK: Comparative Analysis of Incidence & Prevalence of Atopic Dermatitis
2.33. UK: Historic & Projected Volume of Incidence of Atopic Dermatitis cases by Severity Type
2.34. UK: Historic & Projected Volume of Incidence of Atopic Dermatitis cases by Age Group
2.35. UK: Historic & Projected Volume of Prevalence of Atopic Dermatitis cases by Severity Type
2.36. UK: Historic & Projected Volume of Prevalence of Atopic Dermatitis cases by Age Group
2.37. France: Historic & Projected Volume of Incidence & Prevalence of Atopic Dermatitis
2.38. France: Comparative Analysis of Incidence & Prevalence of Atopic Dermatitis
2.39. France: Historic & Projected Volume of Incidence of Atopic Dermatitis cases by Severity Type
2.40. France: Historic & Projected Volume of Incidence of Atopic Dermatitis cases by Age Group
2.41. France: Historic & Projected Volume of Prevalence of Atopic Dermatitis cases by Severity Type
2.42. France: Historic & Projected Volume of Prevalence of Atopic Dermatitis cases by Age Group
2.43. Italy: Historic & Projected Volume of Incidence & Prevalence of Atopic Dermatitis
2.44. Italy: Comparative Analysis of Incidence & Prevalence of Atopic Dermatitis
2.45. Italy: Historic & Projected Volume of Incidence of Atopic Dermatitis cases by Severity Type
2.46. Italy: Historic & Projected Volume of Incidence of Atopic Dermatitis cases by Age Group
2.47. Italy: Historic & Projected Volume of Prevalence of Atopic Dermatitis cases by Severity Type
2.48. Italy: Historic & Projected Volume of Prevalence of Atopic Dermatitis cases by Age Group
2.49. Spain: Historic & Projected Volume of Incidence & Prevalence of Atopic Dermatitis
2.50. Spain: Comparative Analysis of Incidence & Prevalence of Atopic Dermatitis
2.51. Spain: Historic & Projected Volume of Incidence of Atopic Dermatitis cases by Severity Type
2.52. Spain: Historic & Projected Volume of Incidence of Atopic Dermatitis cases by Age Group
2.53. Spain: Historic & Projected Volume of Prevalence of Atopic Dermatitis cases by Severity Type
2.54. Spain: Historic & Projected Volume of Prevalence of Atopic Dermatitis cases by Age Group

3. ATOPIC DERMATITIS MARKET SIZE & OVERVIEW
3.1. 8MM: Historic & Projected Revenue of Atopic Dermatitis
3.2. 8MM: Historic & Projected Revenue of Atopic Dermatitis Snapshot
3.3. 8MM: Major Approved Drugs in Atopic Dermatitis
3.4. 8MM: Historic & Projected Revenue Segmentation by Gender Type, Severity, Age Group & Drug Class
3.5. US: Historic & Projected Revenue of Atopic Dermatitis
3.6. US: Historic & Projected Revenue of Atopic Dermatitis Snapshot
3.7. US: Historic & Projected Revenue Segmentation by Gender Type, Severity, Age Group & Drug Class
3.8. China: Historic & Projected Revenue of Atopic Dermatitis
3.9. China: Historic & Projected Revenue of Atopic Dermatitis Snapshot
3.10. China: Historic & Projected Revenue Segmentation by Gender Type, Severity, Age Group & Drug Class
3.11. Germany: Historic & Projected Revenue of Atopic Dermatitis
3.12. Germany: Historic & Projected Revenue of Atopic Dermatitis Snapshot
3.13. Germany: Historic & Projected Revenue Segmentation by Gender Type, Severity, Age Group & Drug Class
3.14. Japan: Historic & Projected Revenue of Atopic Dermatitis
3.15. Japan: Historic & Projected Revenue of Atopic Dermatitis Snapshot
3.16. Japan: Historic & Projected Revenue Segmentation by Gender Type, Severity, Age Group & Drug Class
3.17. France: Historic & Projected Revenue of Atopic Dermatitis
3.18. France: Historic & Projected Revenue of Atopic Dermatitis Snapshot
3.19. France: Historic & Projected Revenue Segmentation by Gender Type, Severity, Age Group & Drug Class
3.20. Italy: Historic & Projected Revenue of Atopic Dermatitis
3.21. Italy: Historic & Projected Revenue of Atopic Dermatitis Snapshot
3.22. Italy: Historic & Projected Revenue Segmentation by Gender Type, Severity, Age Group & Drug Class
3.23. UK: Historic & Projected Revenue of Atopic Dermatitis
3.24. UK: Historic & Projected Revenue of Atopic Dermatitis Snapshot
3.25. UK: Historic & Projected Revenue Segmentation by Gender Type, Severity, Age Group & Drug Class
3.26. Spain: Historic & Projected Revenue of Atopic Dermatitis
3.27. Spain: Historic & Projected Revenue of Atopic Dermatitis Snapshot
3.28. Spain: Historic & Projected Revenue Segmentation by Gender Type, Severity, Age Group & Drug Class

4. ATOPIC DERMATITIS MARKETED DRUGS OVERVIEW
4.1. Atopic Dermatitis Marketed Drugs – An Overview
4.2. Atopic Dermatitis Marketed Drugs – Summary

5. ATOPIC DERMATITIS PIPELINE DRUGS OVERVIEW
5.1. Atopic Dermatitis Pipeline Drugs – An Overview
5.2. Atopic Dermatitis Pipeline Drugs – Snapshot
5.3. Atopic Dermatitis Pipeline Drugs Overview & Snapshot – By Disease type
5.4. Atopic Dermatitis Pipeline Drugs Overview & Snapshot – By Development Phase
5.5. Atopic Dermatitis Pipeline Drugs Overview & Snapshot – By Route of Administration
5.6. Atopic Dermatitis Pipeline Drugs Overview & Snapshot – By Mechanism of Action
5.7. Atopic Dermatitis Pipeline Drugs Overview & Snapshot – By Molecule type
5.8. Atopic Dermatitis Pipeline Drugs Overview & Snapshot – By Geography type

6. ATOPIC DERMATITIS CLINICAL TRIALS OVERVIEW
6.1. Atopic Dermatitis Clinical Trials Overview Snapshot
6.2. Atopic Dermatitis Clinical Trials Overview – By Recruitment Status
6.3. Atopic Dermatitis Clinical Trials Overview – By Product type
6.4. Atopic Dermatitis Clinical Trials Overview – By Route of Administration
6.5. Atopic Dermatitis Clinical Trials Overview – By Molecule type
6.6. Atopic Dermatitis Clinical Trials Overview – By Geography type

7. ATOPIC DERMATITIS MARKET DYNAMICS
7.1. Atopic Dermatitis Therapeutics Market Drivers
7.2. Atopic Dermatitis Therapeutics Market Constraints
7.3. Atopic Dermatitis Therapeutics Market Trends

8. ATOPIC DERMATITIS COMPETITIVE LANDSCAPE
8.1. Atopic Dermatitis Competitive Landscape – Marketed Drugs
8.2. Key Company Profiles
8.3. Other Key Company Profiles
8.4. Competitive Scenario of Atopic Dermatitis therapeutics market
8.5. Key Company Overviews
8.6. Atopic Dermatitis Competitive Landscape – Pipeline Drugs
8.7. Key Emerging Company Profiles
8.8. Other Key Emerging Company Profiles
8.9. Key Company Overviews

9. ATOPIC DERMATITIS MISCELLANEOUS
9.1. Key Tentative Drug Approvals Timeline
9.2. Key Regulatory Designations
9.3. Key Milestones
9.4. Deals & Collaborations
9.5. Inactive/Discontinued/Dormant Products

10. APPENDIX
10.1. About Arizton
10.2. Research Methodology
10.3. List of Abbreviations

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