IGNE IGENE Biotechnology Inc (CE)

U.S. SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
FORM 10-Q

[X] QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE
SECURITIES EXCHANGE ACT OF 1934

For the quarterly period ended March 31, 2010

[ ] TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF
THE EXCHANGE ACT

For the transition period from __________ to __________

Commission file number 0-15888

 Maryland 52-1230461
_______________________________ ____________________
(State or other jurisdiction of (I.R.S. Employer
incorporation or organization) Identification No.)

Indicate by check mark whether the registrant (1) has filed all reports required to be filed by Section 13 or 15(d) of the Securities Exchange Act of 1934 during the preceding 12 months (or for such shorter period that the registrant was required to file such reports), and (2) has been subject to such filing requirements for the past 90 days.

Yes [X] No [ ]

Indicate by check mark whether the registrant is a large accelerated filer, an accelerated filer, a non-accelerated filer, or a smaller reporting company. See the definitions of "large accelerated filer," "accelerated filer" and "smaller reporting company" in Rule 12b-2 of the Exchange Act.

Large accelerated filer [ ] Accelerated filer [ ] Non-accelerated filer [ ] Smaller reporting company [X]

Indicate by check mark whether the registrant is a shell company (as defined in Rule 12b-2 of the Exchange Act).

Yes [ ] No [X]

APPLICABLE ONLY TO ISSUERS INVOLVED IN BANKRUPTCY PROCEEDINGS DURING THE PRECEEDING FIVE YEARS

Indicate by check mark whether the registrant has filed all documents and reports required to be filed by Section 12, 13 or 15(d) of the Securities Exchange Act of 1934 subsequent to the distribution of securities under a plan confirmed by a court.

Yes [ ] No [X]

Indicate the number of shares outstanding of each of the issuer's classes of common stock, as of the latest practicable date:

 FORM 10-Q
 IGENE Biotechnology, Inc.


 INDEX

 Page
PART I - FINANCIAL INFORMATION 1

 Consolidated Balance Sheets (Unaudited)............................. 1

 Consolidated Statements of Operations (Unaudited)................... 2

 Consolidated Statement of Stockholders' Deficiency (Unaudited)...... 3

 Consolidated Statements of Cash Flows (Unaudited)................... 4

 Notes to Consolidated Financial Statements (Unaudited).............. 5

 Management's Discussion and Analysis of Financial
 Conditions and Results of Operations ............................... 8

 Controls and Procedures............................................. 12

PART II - OTHER INFORMATION ............................................ 14

EXHIBIT INDEX ........................................................... 15

SIGNATURES .............................................................. 16

PART I -- FINANCIAL INFORMATION

Item 1. Financial Statements

 IGENE Biotechnology, Inc. and Subsidiary
 Consolidated Balance Sheets


 March 31, December 31,
 2010 2009
 _____________ _____________
 (Unaudited)
ASSETS
CURRENT ASSETS
 Cash and cash equivalents $ 1,276,195 $ 1,295,222
 Accounts receivable 1,929 1,929
 Due from Naturxan 2,277,292 2,318,085
 Prepaid expenses and other current assets 32,815 44,452
 _____________ _____________
 TOTAL CURRENT ASSETS 3,588,231 3,659,688

 Property and equipment, net 815,213 852,894
 5 year non-compete, net 84,687 92,386
 Intellectual property 149,670 149,670
 Other assets 5,132 5,125
 _____________ _____________
 TOTAL ASSETS $ 4,642,933 $ 4,759,763
 ============= =============

LIABILITIES AND STOCKHOLDERS' DEFICIENCY

CURRENT LIABILITIES
 Accounts payable and accrued expenses $ 451,641 $ 465,405
 Guarantee in debt of Naturxan 1,487,784 1,094,502
 _____________ _____________
 TOTAL CURRENT LIABILITIES 1,939,425 1,559,907

LONG-TERM DEBT
 Notes payable (net of unamortized discount) 363,874 363,874
 Contingent liability on joint venture separation 5,000,000 5,000,000
 Accrued interest 345,337 338,059

REDEEMABLE PREFERRED STOCK
 Carrying amount of redeemable preferred stock, 8% cumulative,
 convertible, voting, series A, $0.01 par value per share.
 Stated value was $21.76 and $21.60, respectively.
 Authorized 1,312,500 shares; issued and outstanding
 11,134 shares. 242,275 240,494
 _____________ _____________
 TOTAL LIABILITIES 7,890,911 7,502,334
 _____________ _____________
COMMITMENTS AND CONTINGENCIES

STOCKHOLDERS' DEFICIENCY
 Common stock --- $0.01 par value per share. Authorized
 3,000,000,000 shares; issued and outstanding 1,565,404,297
 and 1,560,404,297 shares at March 31, 2010 and
 December 31,2009 respectively. 15,654,043 15,604,043
 Additional paid-in capital 34,466,644 34,466,644
 Accumulated deficit (53,420,561) (52,871,514)
 Other comprehensive income 51,896 58,256
 _____________ _____________
 TOTAL STOCKHOLDERS' DEFICIENCY (3,247,978) (2,742,571)
 _____________ _____________

 TOTAL LIABILITIES AND STOCKHOLDERS' DEFICIENCY $ 4,642,933 $ 4,759,763
 ============= =============

The accompanying notes are an integral part of the financial statements.

 IGENE Biotechnology, Inc. and Subsidiary
 Consolidated Statements of Operations
 (Unaudited)


 Three months ended
 ________________________________
 March 31, 2010 March 31, 2009
 _______________ _______________
REVENUE
 Sales $ --- $ 1,241,785
 Cost of sales --- 945,184
 _______________ _______________
 GROSS PROFIT --- 296,601
 _______________ _______________


LOSS OF JOINT VENTURE (393,282) (234,210)

OPERATING EXPENSES

 Marketing and selling 135,579 145,428
 Research, development and pilot plant 469,710 471,037
 General and administrative 73,277 219,377
 Less operating expenses reimbursed by Joint Venture (530,967) (453,419)
 _______________ _______________

 TOTAL OPERATING EXPENSES 147,599 382,423
 _______________ _______________

 OPERATING LOSS (540,881) (320,032)
 _______________ _______________

OTHER INCOME --- 1,025,742

INTEREST EXPENSE (8,166) (8,871)
 _______________ _______________

 NET INCOME (LOSS) $ (549,047) $ 696,839
 _______________ _______________
Other comprehensive income (loss)
 Foreign exchange translation (6,360) 12,002


 TOTAL COMPREHENSIVE INCOME (LOSS) $ (555,407) $ 708,841
 =============== ===============

BASIC AND DILUTED NET INCOME (LOSS) PER COMMON SHARE $ (0.00) $ 0.00
 =============== ===============
WEIGHTED AVERAGE SHARES OUTSTANDING 1,562,726,519 1,518,503,841
 =============== ===============








The accompanying notes are an integral part of the financial statements.

 IGENE Biotechnology, Inc. and Subsidiary
 Consolidated Statement of Stockholders' Deficiency
 (Unaudited)



 Additional Other Total
 Common Stock Paid-in Accumulated Comprehensive Stockholders'
 (shares/amount) Capital Deficit Income Deficiency
 _____________________________ _____________ _____________ _____________ _____________

Balance at January 1, 2010 1,560,404,297 $ 15,604,043 $ 34,466,644 $(52,871,514) $ 58,256 $ (2,742,571)

Shares issue for service 5,000,000 50,000 --- --- --- 50,000


Loss due to currency translation --- --- --- --- (6,360) (6,360)

Net loss for the three months ended
 March 31, 2010 --- --- --- (549,047) --- (549,047)
 _______________ _____________ _____________ _____________ _____________ _____________

Balance at March 31, 2010 1,565,404,297 $ 15,654,043 $ 34,466,644 $(53,420,561) $ 51,896 $ (3,247,978)
 =============== ============= ============= ============= ============= =============




The accompanying notes are an integral part of the financial statements.

 IGENE Biotechnology, Inc. and Subsidiary
 Consolidated Statements of Cash Flows
 (Unaudited)

 Three months ended
 _________________________________
 March 31, 2010 March 31, 2009
 _______________ _______________
Cash flows from operating activities
 Net loss $ (549,047) $ (220,999)
 Adjustments to reconcile net loss to net cash used in
 operating activities:
 Depreciation 37,681 42,035
 Increase in preferred stock for cumulative dividend
 classified as interest 1,781 1,773
 Recoupment from (Advances to) Joint Venture 40,880 (453,419)
 Shares issued for services 50,000 ---
 Amortization of customer contracts and non-compete 7,699 7,699
 Loss of joint venture 393,282 234,209
 Decrease (increase) in:
 Accounts receivable --- 54,932
 Inventory --- 840,436
 Prepaid expenses and other current assets 11,544 (45,340)
 Increase (decrease) in:
 Accounts payable and accrued expenses (6,487) (820,818)
 _______________ _______________
 Net cash used in operating activities (12,667) (359,492)
 _______________ _______________

Cash flows from investing activities
 Purchase of equipment --- (202,963)
 Net cash used in investing activities --- (202,963)
 _______________ _______________

Cash flows from financing activities
 Net cash provided by financing activities --- ---
 _______________ _______________

Gain due to currency translation (6,360) 12,002

 Net increase (decrease) in cash and cash equivalents (19,027) 550,453

 Cash and cash equivalents
 at beginning of period 1,295,222 1,488,011

 Cash and cash equivalents
 at end of period $ 1,276,195 $ 937,558
 =============== ===============
Supplementary disclosure and cash flow information
__________________________________________________

Cash paid for interest $ --- $ ---
Cash paid for income taxes --- ---

See Note (3) for non-cash investing and financing activities.





The accompanying notes are an integral part of the financial statements.

IGENE Biotechnology, Inc. and Subsidiary

Notes to Consolidated Financial Statements

(Unaudited)

(1) Unaudited Consolidated Financial Statements

The March 31, 2010 consolidated financial statements presented herein are unaudited, and in the opinion of management, include all adjustments (consisting only of normal recurring accruals) necessary for a fair presentation of financial position, results of operations and cash flows. Such financial statements do not include all of the information and footnote disclosures normally included in financial statements prepared in accordance with accounting principles generally accepted in the United States of America. This quarterly report on Form 10-Q should be read in conjunction with the Annual Report on Form 10-K for IGENE Biotechnology, Inc. ("Igene") for the year ended December 31, 2009 and filed with the SEC on March 31, 2010. The December 31, 2009 consolidated balance sheet is derived from the audited balance sheet included therein.

(2) Nature of Operations

IGENE Biotechnology, Inc. ("Igene" or the "Company") was incorporated in the State of Maryland on October 27, 1981 to develop, produce and market value-added specialty biochemical products. Igene is a supplier of natural astaxanthin, an essential nutrient in different feed applications and a source of pigment for coloring farmed salmon species. Igene is also venturing to supply astaxanthin as a nutraceutical ingredient. Igene is focused on research and development in the areas of fermentation technology, nutrition and health and the marketing of products and applications worldwide. Igene is the developer of AstaXin(R), a natural astaxanthin product made from yeast, which is used as a source of pigment for coloring farmed salmonids.

Igene has devoted its resources to the development of proprietary processes to convert selected agricultural raw materials or feedstocks into commercially useful and cost effective products for the food, feed, flavor and agrochemical industries. In developing these processes and products, Igene has relied on the expertise and skills of its in-house scientific staff and, for special projects, various consultants.

In 2000, Igene formed a wholly-owned subsidiary, Igene Chile Comercial, Ltda., in Chile. The subsidiary has a sales and customer service office in Puerto Varas, Chile, and a product warehouse in Puerto Montt, Chile.

In an effort to develop a dependable source of production, on March 19, 2003, Tate & Lyle PLC ("Tate") and Igene announced a 50:50 joint venture to produce AstaXin(R) for the aquaculture industry. Production utilized Tate's fermentation capability together with the unique technology developed by Igene. Part of Tate's existing citric acid facility located in Selby, England, was modified to include the production of this product. Tate's investment of approximately $24,600,000 included certain of its facility assets that were used in citric acid production. Igene's contribution to the venture, including its intellectual property and its subsidiary in Chile, was valued by the parties as approximately equal to Tate's contribution. For accounting purposes Igene's accounting contribution was valued at zero.

On October 31, 2007, Igene and Tate entered into a Separation Agreement pursuant to which the venture was terminated. As part of the Separation Agreement, Igene sold to Tate its 50% interest in the venture and the venture sold to Igene its intellectual property, inventory and certain assets and lab equipment utilized by the venture as well as Igene's subsidiary in Chile. The purchase price paid by Tate to Igene for its 50% interest in the venture was 50% of the venture's net working capital. The purchase price paid by Igene for the inventory was an amount equal to 50% of the venture's net working capital, the assumption of various liabilities and the current market price of the inventory, less specified amounts. In addition, Igene agreed to pay to Tate an amount equal to 5% of Igene's gross revenues from the sale of astaxanthin up to a maximum of $5,000,000. Tate agreed for a period of five years not to engage in the astaxanthin business.

On January 8, 2009, Igene entered into an agreement with Archer-Daniels-Midland Company ("ADM") pursuant to which the Company and ADM formed a joint venture (the "ADM JV") to manufacture and sell astaxanthin and derivative products throughout the world. Each of the Company and ADM has a 50% ownership interest in the ADM JV and has equal representation on the Board of Managers of the ADM JV.

IGENE Biotechnology, Inc. and Subsidiary

Notes to Consolidated Financial Statements

(continued)

(3) Noncash Investing and Financing Activities

During the three months ended March 31, 2010 and 2009, the Company recorded in each quarter dividends in arrears on 8% redeemable preferred stock cumulating at $0.16 per share aggregating to $1,781 and $1,773, respectively.

(4) Stockholders' Deficiency

As of March 31, 2010, 22,268 shares of authorized but unissued common stock were reserved for issue upon conversion of the Company's outstanding preferred stock.

As of March 31, 2010, 656,428 shares of authorized but unissued common stock were reserved for the exercise of outstanding warrants.

(5) Basic and Diluted Net Loss per Common Share

Basic and diluted net loss per common share for the three- month periods ended March 31, 2010 and 2009 are based on 1,562,726,519 and 1,518,503,841shares of weighted average common shares outstanding, respectively. No adjustment has been made for any common stock equivalents outstanding because their effects would be anti-dilutive. As of March 31, 2010, potential full dilution was 1,566,082,993 shares.

(6) Going Concern

Igene has incurred net losses in each year of its existence, aggregating approximately $53,421,000 from inception to March 31, 2010 and as of March 31, 2010, Igene's liabilities exceeded its assets by approximately $3,248,000. These factors indicate that Igene may not be able to continue in existence unless it is able to raise additional capital and attain profitable operations.

As discussed, as of October 31, 2007, Igene terminated its relationship with Tate & Lyle. Igene maintained the saleable inventory after the termination of the relationship. Igene sold the existing inventory in order to maintain its relationship with customers and used these funds to cover expenses.

On January 8, 2009, Igene entered into an agreement with Archer-Daniels-Midland Company ("ADM") pursuant to which the Company and ADM formed a joint venture (the "ADM JV") to manufacture and sell astaxanthin and derivative products throughout the world. Each of the Company and ADM has a 50% ownership interest in the ADM JV and has equal representation on the Board of Managers of the ADM JV.

(7) Naturxan LLC

ADM has provided a working line of credit to the ADM JV bearing interest at the rate of 4% in excess of the one year LIBOR. As part of the ADM JV agreement both Igene and ADM agreed to provide a Guarantee for 50% of the indebtedness of the new venture Naturxan, LLC, up to $1,612,500. The $2,277,292 due from Naturxan is for services provided by Igene to the ADM JV. These fees are payable within 30 days of the receipt of the invoice. Unpaid invoices will accrue interest at the six month LIBOR.

Manufacturing is underway at the ADM facility. Management expects continued dependable production. As of the end of the first quarter of 2010, Igene has not made an investment in the ADM JV.

IGENE Biotechnology, Inc. and Subsidiary

Notes to Consolidated Financial Statements

(Unaudited)

(continued)

(8) Forgiveness of Debt

The March 31, 2009 financials reflect the recording of a gain of $1,025,742. This is a one-time occurrence related to a liability recorded in a prior period related to the termination of the joint venture with Tate & Lyle. On February 26, 2009, Igene signed a settlement agreement of past obligations and made a final payment to Tate & Lyle in the amount of $714,227. At the termination of the joint venture, Igene recorded liabilities of $890,000 for payments of past payables of the joint venture as well as $51,000 for costs related to collection of receivables of the joint venture. The expense was recorded when it was thought Igene could be liable for such amount it. Apart from the $5,000,000 liability related to future revenue (see Note 2), Igene has fulfilled all of its payment obligations to Tate & Lyle.

(9) Issuance of Restricted Shares

The compensation committee and the board of directors recommended the issuance of 5,000,000 shares of Common Stock of Igene Biotechnology, Inc. (par value $.01 per share), at $.01 per share, the market price on February 19, 2010 to its Manufacturing Consultant, Joseph Downs, in recognition for his work in helping to facilitate the production process at the new facility. These shares were issued in the first quarter of 2010, and they were expensed as part of marketing and selling expense in the period.

IGENE Biotechnology, Inc. and Subsidiary

Management's Discussion and Analysis of Financial Condition and Results of Operations

Item 2. Management's Discussion and Analysis of Financial Condition and Results of Operations

CAUTIONARY STATEMENTS FOR PURPOSES OF "SAFE HARBOR PROVISIONS" OF THE PRIVATE SECURITIES LITIGATION REFORM ACT OF 1995:

EXCEPT FOR HISTORICAL FACTS, ALL MATTERS DISCUSSED IN THIS REPORT, WHICH ARE FORWARD-LOOKING, INVOLVE A HIGH DEGREE OF RISK AND UNCERTAINTY. CERTAIN STATEMENTS IN THIS REPORT SET FORTH MANAGEMENT'S INTENTIONS, PLANS, BELIEFS, EXPECTATIONS OR PREDICTIONS OF THE FUTURE BASED ON CURRENT FACTS AND ANALYSES. WHEN WE USE THE WORDS "BELIEVE," "EXPECT," "ANTICIPATE," "ESTIMATE," "INTEND" OR SIMILAR EXPRESSIONS, WE INTEND TO IDENTIFY FORWARD-LOOKING STATEMENTS. YOU SHOULD NOT PLACE UNDUE RELIANCE ON THESE FORWARD-LOOKING STATEMENTS. ACTUAL RESULTS MAY DIFFER MATERIALLY FROM THOSE INDICATED IN SUCH STATEMENT, DUE TO A VARIETY OF FACTORS, RISKS AND UNCERTAINTIES. POTENTIAL RISKS AND UNCERTAINTIES INCLUDE, BUT ARE NOT LIMITED TO, COMPETITIVE PRESSURES FROM OTHER COMPANIES WITHIN THE BIOTECH AGRICULTURE AND AQUACULTURE INDUSTRIES, ECONOMIC CONDITIONS IN THE COMPANY'S PRIMARY MARKETS, EXCHANGE RATE FLUCTUATIONS, REDUCED PRODUCT DEMAND, INCREASED COMPETITION, INABILITY TO PRODUCE REQUIRED CAPACITY, UNAVAILABILITY OF FINANCING, GOVERNMENT ACTION, WEATHER CONDITIONS AND OTHER UNCERTAINTIES, INCLUDING THOSE DETAILED IN "RISK FACTORS" THAT ARE INCLUDED FROM TIME-TO-TIME IN THE COMPANY'S SECURITIES AND EXCHANGE COMMISSION FILINGS. THE COMPANY ASSUMES NO DUTY TO UPDATE FORWARD-LOOKING STATEMENTS TO REFLECT EVENTS OR CIRCUMSTANCES AFTER THE DATE OF SUCH STATEMENTS.

Except as otherwise provided herein, the preparation of our financial statements in conformity with accounting principles generally accepted in the United States (or "GAAP") requires management to make judgments, assumptions and estimates that affect the amounts reported in our financial statements and accompanying notes. Actual results could differ materially from those estimates. The following are critical accounting policies important to our financial condition and results of operations presented in the financial statements and require management to make judgments and estimates that are inherently uncertain:

Revenue from product sales are recognized when there is persuasive evidence that an arrangement exists, delivery has occurred, the price is fixed and determinable, and collectability is reasonably assured. Allowances are established for estimated uncollectible amounts, product returns and discounts.

The Joint Venture and the ADM Joint Venture was accounted for under the equity method of accounting as Igene has a 50% ownership interest.

Igene will recognize the loss of the ADM Joint Venture beyond the investment and advances to the ADM Joint Venture, to the point Igene maintains guarantees in the debt of the ADM Joint Venture.

IGENE Biotechnology, Inc. and Subsidiary

Management's Discussion and Analysis of Financial Condition and Results of Operations

(Continued)

Sales and other revenue

For the quarter ended March 31, 2009, Igene recorded sales in the amount of $1,241,785. Sales had been limited in past years due to insufficient production quantity and limited in the current period as source of production is being developed and production begins in the new ADM JV. Management believes that this new ADM JV will provide salable product that will allow Igene to be competitive in the market place and allow for increased sales in the future, though no assurances can be provided in this matter. All future sales of the ADM JV product will be recorded through the joint venture.

Cost of sales and gross profit

For the quarter ended March 31, 2009, Igene recorded cost of sales in the amount of $945,184. This resulted in a gross profit of $296,601, or 24% for the period ended March 31, 2009. The gross profit is due mainly to the discount in which the product was purchased at the conclusion of the joint venture with Tate and Lyle. As with sales, with the termination of the joint venture with Tate and Lyle, there can be no assurance of the continued dependability of production. Sales had been limited in past years due to insufficient production quantity and limited in the current period as a source of production is being developed and production begins in the new ADM JV. Management believes that this new ADM JV will provide salable product that will allow Igene to be competitive in the market place and allow for increased sales in the future, though no assurances can be provided in this matter. As a result, future cost of sales is expected to increase as a new source of production is developed. All future cost of sales on the ADM JV product will be recorded through the joint venture.

Loss of Joint Venture

For the quarter ended March 31, 2010, Igene recorded a loss from the ADM JV of $393,282. On January 8, 2009, Igene entered into an agreement with Archer-Daniels-Midland Company ("ADM") pursuant to which the Company and ADM formed a joint venture (the "ADM JV") to manufacture and sell astaxanthin and derivative products throughout the world. Each of the Company and ADM has a 50% ownership interest in the ADM JV and has equal representation on the Board of Managers of the ADM JV.

On October 31, 2007, Igene terminated its relationship with Tate & Lyle. Igene maintained the saleable inventory after the termination of the relationship. Igene sold the existing inventory in order to maintain its relationship with customers and used these funds to cover expenses. The new ADM JV began selling product in the 3rd quarter of 2009. For the three months ended March 31, 2010, revenues from sales of product were $2,590,572. Cost of sales for the three months ended March 31, 2010 were $2,477,238 resulting in a gross profit of $113,334 or 4%. Expenses recorded by the ADM JV were $899,898 resulting in a net loss of $786,564 for the three months ended March 31, 2010. Igene's 50% interest resulted in the $393,282 loss recorded. Management believes that this new ADM JV will provide saleable product that will allow Igene to be competitive in the market place and allow for increased sales in the future, though no assurances can be provided in this matter.

Marketing and selling expenses

For the quarters ended March 31, 2010 and 2009, Igene recorded marketing and selling expense in the amounts of $135,579 and $145,428, respectively, a decrease of $9,849, or 7%. With the creation of the ADM JV, responsibility for the marketing and selling function is being assumed by the Joint Venture. It is expected that marketing and selling expenses will fluctuate as activities continue to maintain customer base through the period of transition in which the development of production continues. However, no assurances can be made with regard to a new source of production or the maintenance of the customer base. Expenses are expected to be funded by the new ADM JV and cash flows from operations, to the extent available for such purposes. During the three months ended March 31, 2010, $55,620 of the marketing cost was reimbursed by the ADM JV.

IGENE Biotechnology, Inc. and Subsidiary

Management's Discussion and Analysis of Financial Condition and Results of Operations

(Continued)

Research, development and pilot plant expenses

For the quarters ended March 31, 2010 and 2009, Igene recorded research and development expenditures in the amount of $469,710 and $471,037, respectively, a decrease of $1,327 or less than 1%. Research and development is underway to develop new uses for its product. It is expected these expenditures will remain at current levels in support of increasing the efficiency of the manufacturing process through experimentation in the Company's pilot plant, developing higher yielding strains of yeast and other improvements in the Company's AstaXin(R) technology. Expenses are expected to be funded by the new ADM JV and cash flows from operations, to the extent available for such purposes. During the three month period ended March 31, 2010, $460,347 of the research and development expenditures was reimbursed by the ADM JV.

General and administrative expenses

General and administrative expenses for the quarters ended March 31, 2010 and 2009 were $73,277 and $219,377 respectively, a decrease of $146,100 or 67%. Igene expects general and administrative expenditures at the current level. Igene works to reduce the level of overhead expenditures and spend funds on research and development efforts. A small portion of this expense is expected to be covered by the ADM JV, but the majority of these expenses are expected to be paid from cash flows from operations, to the extent available for such purposes. Of the 2010 general and administrative expenditures, $15,000 was reimbursed by the ADM JV.

Expenses reimbursed by ADM Joint Venture

As part of the ADM Joint Venture Agreement, a portion of costs incurred by Igene related to production, research and development, those related to the marketing of AstaXin(R), as well as those expenditures related to general and administrative functions of the Joint Venture are considered expenditures of the Joint Venture and therefore will be reimbursed by the ADM JV. For the three months ended March 31, 2010, the ADM JV reimbursed Igene $530,967 for $460,347 for research and development expenditures, $55,620 for marketing expenditures, and $15,000 for general and administrative expenditures.

Other income

Igene had other income for the quarter ended March 31, 2009 of $1,025,742. Such income for 2009 was a one-time occurrence related to a liability recorded in a prior period in connection with the termination of the joint venture with Tate & Lyle. On February 26, 2009, Igene signed a settlement agreement of past obligations and made a final payment to T&L in the amount of $714,227. At the termination of the joint venture, Igene recorded liabilities of $890,000 for payments of past payables of the joint venture as well as $51,000 for expenditures related to collection of receivables of the joint venture. This was a one- time occurrence related to a liability recorded in a prior period related to the termination of the joint venture with Tate and Lyle. The expense was recorded when it was thought Igene could be liable for such amount. Apart from the $5,000,000 liability related to future revenue (see note 2), Igene has fulfilled all of its payment obligations to Tate & Lyle.

Interest expense

Interest expense for the quarters ended March 31, 2009 were $8,166 and $8,871 respectively, a decrease of $705 or 8%. This interest expense (net of interest income) was for interest on Igene's long term financing from its directors and other stockholders, interest on Igene's subordinated and convertible debentures.

IGENE Biotechnology, Inc. and Subsidiary

Management's Discussion and Analysis of Financial Condition and Results of Operations

(Continued)

Net loss and basic and diluted net loss per common share

As a result of the foregoing, the Company reported comprehensive loss of $549,047 and comprehensive income of $708,841, respectively, for the quarters ended March 31, 2010 and 2009. This represents a loss of $0.00 and a gain of $0.00 per basic and diluted common share in each of the quarters ended March 31, 2010 and 2009, respectively. The weighted-average number of shares of common stock outstanding of 1,562,726,519 and 1,518,503,841 for the quarters ended March 31, 2010 and 2009, respectively, has increased due to shares issued in repurchase of employee stock options.

Financial Position

During the quarters ended March 31, 2010 and 2009, in addition to the matters previously discussed, the following actions also materially affected the Company's financial position:

- For 2010 most activity took place as part of the ADM JV and effects to cash were minimal, Mainly decreases in prepaid expenses and other assets were a use of cash of $11,544; and

- Decreases in accounts receivable and inventory for the quarter ended March 31, 2009 of $895,368 were a source of cash, offset by funds used to decrease accounts payable and accrued expenses by $820,818; and

- The carrying value of redeemable preferred stock was increased and interest expense was recorded in the amount of $1,781 and $1,773, respectively, in 2010 and 2009, reflecting cumulative unpaid dividends on redeemable preferred stock.

In December 1988, as part of an overall effort to contain costs and conserve working capital, Igene suspended payment of the quarterly dividend on its preferred stock, though this dividend still accrues. Any resumption of the dividend would require significant improvements in cash flow. Unpaid dividends will accrue for future payment or addition to the liquidation preference or redemption value of the preferred stock. As of March 31, 2010, total dividends in arrears on Igene's preferred stock total $153,204 ($13.76 per share) and are included in the carrying value of the redeemable preferred stock.

Liquidity and Capital Resources

Historically, Igene has been funded primarily by equity contributions and loans from stockholders. As of March 31, 2010, Igene had working capital of $1,648,806, and cash and cash equivalents of $1,276,195.

Cash used by operating activities during the three-month period ended March 31, 2010 and March 31, 2009 equaled $12,667 and $359,492, respectively. The reduction is mainly attributable to the reduction of funds advanced to the joint venture between 2009 and 2010.

Cash used by investing activities during the three-month period ended March 31, 2009 equaled $202,963, all used in equipment purchase. No equipment was purchased in the first quarter of 2010, and there were no funds used in investing activity.

No cash was used or provided by financing activities during the first quarter of 2010 or 2009.

IGENE Biotechnology, Inc. and Subsidiary

Management's Discussion and Analysis of Financial Condition and Results of Operations

(Continued)

Over the next twelve months, Igene believes it will need additional working capital. Part of this funding is expected to be received from sales of AstaXin(R), resulting in increased cash. Additional funding is expected through the ADM JV reimbursement of expenses. There will be additional delay between the commencement of production and the receipt of proceeds from any sale of such product. However, there can be no assurance that projected cash from sales, or additional funding, will be sufficient for Igene to fund its continued operations.

The Company does not believe that inflation had a significant impact on its operations during the three-month periods ended March 31, 2010 and 2009.

There have been no material changes in the risks related to off-balance sheet arrangements since the Company's disclosure in its Annual Report on Form 10-K for the year ended December 31, 2009.

Item 3. Quantitative and Qualitative Disclosure About Market Risk

The Company is a smaller reporting company as defined by Rule 12b-2 of the Securities Exchange Act of 1934, as amended (the "Exchange Act") and is not required to provide the information required under this item.

Item 4. Controls and Procedures

We carried out an evaluation, under the supervision and with the participation of our management, including our principal executive officer and principal financial officer, of the effectiveness of our disclosure controls and procedures (as defined in Rules 13a-15(e) and 15d-15(e) of the Exchange Act). Based upon that evaluation, our principal executive officer and principal financial officer concluded that, as of the end of the period covered in this report, our disclosure controls and procedures were not effective to ensure that information required to be disclosed in reports filed under the Exchange Act is recorded, processed, summarized and reported within the required time periods and is accumulated and communicated to our management, including our principal executive officer and principal financial officer, as appropriate to allow timely decisions regarding required disclosure.

Our management, including our principal executive officer and principal financial officer, does not expect that our disclosure controls and procedures or our internal controls will guaranty the prevention of any error or fraud. A control system, no matter how well conceived and operated, can provide only reasonable, not absolute, assurance that the objectives of the control system are met. Further, the design of a control system must reflect the fact that there are resource constraints and the benefits of controls must be considered relative to their costs. Due to the inherent limitations in all control systems, no evaluation of controls can provide absolute assurance that all control issues and instances of fraud, if any, have been detected. To address the material weaknesses, we performed additional analysis and other post-closing procedures in an effort to ensure our consolidated financial statements included in this annual report have been prepared in accordance with GAAP. Accordingly, management believes that the financial statements included in this report fairly present in all material respects our financial condition, results of operations and cash flows for the periods presented.

Igene is undertaking to improve its internal control over financial reporting and improve its disclosure controls and procedures. As of December 31 2009, we identified the following material weaknesses which still exist as of March 31, 2010 and through the date of this report.

IGENE Biotechnology, Inc. and Subsidiary

Management's Discussion and Analysis of Financial Condition and Results of Operations

(Continued)

1. As of March 31, 2010, we did not maintain effective controls over the control environment. Specifically, we have not formally adopted a written code of business conduct and ethics that governs the Company's employees, officers and directors. Additionally, we have not developed and effectively communicated to our employees its accounting policies and procedures. This has resulted in inconsistent practices. Further, the Board of Directors does not currently have any independent members and no director qualifies as an independent audit committee financial expert as defined in Item 407(d)(5)(ii) of Regulation S-K. Since these entity level programs have a pervasive effect across the organization, management has determined that these circumstances constitute a material weakness.

2. As of March 31, 2010, we did not maintain effective controls over financial statement disclosure. Specifically, controls were not designed and in place to ensure that all disclosures required were originally addressed in our financial statements. Accordingly, management has determined that this control deficiency constitutes a material weakness.

3. As of March 31, 2010, we did not maintain effective controls over equity transactions. Specifically, controls were not designed and in place to ensure that equity transactions were properly reflected. Accordingly, management has determined that this control deficiency constitutes a material weakness.

IGENE Biotechnology, Inc. and Subsidiary

PART II
OTHER INFORMATION

Item 1. Legal Proceedings

There are no material pending legal proceedings to which Igene is a party or to which any of Igene's properties are subject; nor are there material proceedings known to be contemplated by any governmental authority; nor are there material proceedings known to Igene, pending or contemplated, in which any of Igene's directors, officers, affiliates or any principal security holders, or any associate of any of the foregoing, is a party or has an interest adverse to us.

Item 1A. Risk Factors

The Company is a smaller reporting company as defined by Rule 12b-2 of the Exchange Act and is not required to provide the information required under this item.

Item 2. Unregistered Sales of Equity Securities and Use of Proceeds

None.

Item 3. Defaults Upon Senior Securities

In December 1988, as part of an overall effort to contain costs and conserve working capital, Igene suspended payment of the quarterly dividend on its preferred stock, though this dividend still accrues. Any resumption of the dividend would require significant improvements in cash flow. Unpaid dividends will accrue for future payment or addition to the liquidation preference or redemption value of the preferred stock. As of March 31, 2010, total dividends in arrears on Igene's preferred stock total $153,204 ($13.76 per share) and are included in the carrying value of the redeemable preferred stock.

Item 4. Submission of Matters to a Vote of Security Holders

None.

Item 5. Other Information

None.

Item 6. Exhibits

(a) Exhibits

EXHIBIT DESCRIPTION
NO.

3.1 Articles of Incorporation of the Registrant, as

amended as of November 17, 1997, constituting Exhibit 3.1 to the Registration Statement No. 333- 41581 on Form SB-2 filed with the SEC on December 5, 1997, are hereby incorporated by reference.

3.2 Articles of Amendment to Articles of Incorporation of the Registrant, constituting Exhibit 3.1(b) to the Registration Statement No. 333-76616 on Form S- 8 filed with the SEC on January 11, 2002, are hereby incorporated by reference.

3.3 By-Laws of the Registrant, constituting Exhibit 3.2 to the Registration Statement No. 33-5441 on Form S- 1 filed with the SEC on May 6, 1986, are hereby incorporated by reference.

31.1 Rule 13a-14(a) or 15d-14(a) Certification of the Registrant's principal executive officer.*

31.2 Rule 13a-14(a) or 15d-14(a) Certification of the Registrant's principal financial officer.*

32.1 Rule 13a-14(b) or 15d-14(b) Certification of the Registrant's principal executive officer pursuant to 18 U.S.C. Section 1350 as adopted pursuant to Rule 906 of the Sarbanes-Oxley Act of 2002.*

32.2 Rule 13a-14(b) or 15d-14(b) Certification of the Registrant's principal financial officer pursuant to 18 U.S.C. Section 1350 as adopted pursuant to Rule 906 of the Sarbanes-Oxley Act of 2002.*

*Filed herewith.

SIGNATURES

Pursuant to the requirements of the Securities Exchange Act of 1934, the registrant has duly caused this report to be signed on its behalf by the undersigned, thereunto duly authorized.

Date May 14, 2010 By /S/ STEPHEN F. HIU
 _____________ _____________________________________
 STEPHEN F. HIU
 President
 (principal executive officer)




Date May 14, 2010 By /S/ EDWARD J. WEISBERGER
 _____________ _____________________________________
 EDWARD J. WEISBERGER
 Chief Financial Officer
 (principal financial officer)

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