FORM 4
[ X ] Check this box if no longer subject to Section 16. Form 4 or Form 5 obligations may continue. See Instruction 1(b).         
UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549

STATEMENT OF CHANGES IN BENEFICIAL OWNERSHIP OF SECURITIES
                                                                                  
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Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934 or Section 30(h) of the Investment Company Act of 1940
                      

1. Name and Address of Reporting Person *

Warekois Tom E 		2. Issuer Name and Ticker or Trading Symbol

IRIS INTERNATIONAL INC [ IRIS ] 		5. Relationship of Reporting Person(s) to Issuer (Check all applicable)

_____ Director                      _____ 10% Owner
__ X __ Officer (give title below)      _____ Other (specify below)
Corp VP, Pres IRIS Diagnostics
(Last)          (First)          (Middle)

C/O IRIS INTERNATIONAL, INC., 9158 ETON AVENUE 		3. Date of Earliest Transaction (MM/DD/YYYY)

10/31/2012
(Street)

CHATSWORTH, CA 91311
(City)        (State)        (Zip)
4. If Amendment, Date Original Filed (MM/DD/YYYY)

 
6. Individual or Joint/Group Filing (Check Applicable Line)

_ X _ Form filed by One Reporting Person
___ Form filed by More than One Reporting Person

Table I - Non-Derivative Securities Acquired, Disposed of, or Beneficially Owned
1.Title of Security
(Instr. 3) 		2. Trans. Date 2A. Deemed Execution Date, if any 3. Trans. Code
(Instr. 8) 		4. Securities Acquired (A) or Disposed of (D)
(Instr. 3, 4 and 5) 		5. Amount of Securities Beneficially Owned Following Reported Transaction(s)
(Instr. 3 and 4) 		6. Ownership Form: Direct (D) or Indirect (I) (Instr. 4) 7. Nature of Indirect Beneficial Ownership (Instr. 4)
Code V Amount (A) or (D) Price
Common Stock   10/31/2012     U    22734   D $19.50   0   D    
Common Stock   10/31/2012     M    29167   A $11.65   29167   D    
Common Stock   10/31/2012     M    43982   A $9.99   73149   D    
Common Stock   10/31/2012     M    19848   A $11.97   92997   D    
Common Stock   10/31/2012     M    5317   A $9.81   98314   D    
Common Stock   10/31/2012     M    2417   A $9.81   100731   D    
Common Stock   10/31/2012     F (1)    70435   D $19.50   30296   D    
Common Stock   10/31/2012     S (2)    30296   D $19.50   0   D    

Table II - Derivative Securities Beneficially Owned ( e.g. , puts, calls, warrants, options, convertible securities)
1. Title of Derivate Security
(Instr. 3) 		2. Conversion or Exercise Price of Derivative Security 3. Trans. Date 3A. Deemed Execution Date, if any 4. Trans. Code
(Instr. 8) 		5. Number of Derivative Securities Acquired (A) or Disposed of (D)
(Instr. 3, 4 and 5) 		6. Date Exercisable and Expiration Date 7. Title and Amount of Securities Underlying Derivative Security
(Instr. 3 and 4) 		8. Price of Derivative Security
(Instr. 5) 		9. Number of derivative Securities Beneficially Owned Following Reported Transaction(s) (Instr. 4) 10. Ownership Form of Derivative Security: Direct (D) or Indirect (I) (Instr. 4) 11. Nature of Indirect Beneficial Ownership (Instr. 4)
Code V (A) (D) Date Exercisable Expiration Date Title Amount or Number of Shares
Stock Option (Right to Buy)   $11.65   10/31/2012     M         29167      (3) 3/4/2013   Common Stock   29167   $0   0   D    
Stock Option (Right to Buy)   $9.99   10/31/2012     M         43982      (4) 2/20/2016   Common Stock   43982   $0   6284   D    
Stock Option (Right to Buy)   $11.97   10/31/2012     M         19848      (5) 2/23/2017   Common Stock   19848   $0   11910   D    
Stock Option (Right to Buy)   $9.81   10/31/2012     M         5317      (6) 2/24/2018   Common Stock   5317   $0   8862   D    
Stock Option (Right to Buy)   $9.81   10/31/2012     M         2417      (6) 2/24/2018   Common Stock   2417   $0   4029   D    
Stock Option (Right to Buy)   $9.99   10/31/2012     D         6284      (7) 2/20/2016   Common Stock   6284   $9.51   0   D    
Stock Option (Right to Buy)   $11.97   10/31/2012     D         11910      (7) 2/23/2017   Common Stock   11910   $7.53   0   D    
Stock Option (Right to Buy)   $9.81   10/31/2012     D         8862      (7) 2/24/2018   Common Stock   8862   $9.69   0   D    
Stock Option (Right to Buy)   $9.81   10/31/2012     D         4029      (7) 2/24/2018   Common Stock   4029   $9.69   0   D    
Performance Restricted Stock Units     (8) 10/31/2012     A      12800         (9)   (9) Common Stock   12800   $0   12800   D    
Performance Restricted Stock Units     (8) 10/31/2012     D         12800      (9)   (9) Common Stock   12800   $19.50   0   D    
Restricted Stock Units     (8) 10/31/2012     D         1755      (10)   (10) Common Stock   1755   $19.50   0   D    
Restricted Stock Units     (8) 10/31/2012     D         5157      (10)   (10) Common Stock   5157   $19.50   0   D    
Restricted Stock Units     (8) 10/31/2012     D         12800      (10)   (10) Common Stock   12800   $19.50   0   D    
Restricted Stock Units     (8) 10/31/2012     D         25600      (10)   (10) Common Stock   25600   $19.50   0   D    

Explanation of Responses:
( 1)  The shares were retained by the company in payment of the exercise price and/or withholding taxes incurred in connection with the exercise of options.
( 2)  Pursuant to a Tender and Support Agreement dated September 17, 2012 by and among each director and officer of IRIS International, Inc., IRIS International, Inc., Danaher Corporation and Daphne Acquisition Corporation, the reporting person sold these shares of Common Stock to Daphne Acquisition Corporation in exchange for consideration of $19.50 per share.
( 3)  Vested 25% on March 4, 2009, and thereafter 6.25% vested in 12 equal quarterly installments with the first such installment vesting on June 30, 2009.
( 4)  Vested 25% on February 20, 2010, and thereafter 6.25% will vest / vested in 12 equal quarterly installments with the first such installment vesting on June 30, 2010.
( 5)  Vested 25% on February 23, 2011, and thereafter 6.25% will vest / vested in 12 equal quarterly installments with the first such installment vesting on June 30, 2011.
( 6)  Vested 25% on February 24, 2012, and thereafter 6.25% will vest / vested in 12 equal quarterly installments with the first such installment vesting on June 30, 2012.
( 7)  Pursuant to the Agreement and Plan of Merger dated September 17, 2012 by and among Danaher Corporation, Daphne Acquisition Corporation and IRIS International, Inc. (the "Merger Agreement"), this option vested in full and was cancelled in the merger in exchange for a cash amount equal to the number of shares underlying this option multiplied by the difference between the per share merger consideration of $19.50 and the per share exercise price of this option.
( 8)  Each restricted stock unit represents a contingent right to receive one share of IRIS International, Inc. common stock.
( 9)  Pursuant to the Merger Agreement, these performance restricted stock units, which were granted on February 27, 2012 and were subject to performance-based and time-based vesting, vested in full at the target level of performance and were cancelled in the merger in exchange for a cash amount equal to the number of shares underlying the performance restricted stock units multiplied by the per share merger consideration of $19.50.
( 10)  Pursuant to the Merger Agreement, these restricted stock units vested in full and were cancelled in the merger in exchange for a cash amount equal to the number of shares underlying the restricted stock units multiplied by the per share merger consideration of $19.50.

Reporting Owners
Reporting Owner Name / Address
Relationships
Director 10% Owner Officer Other
Warekois Tom E
C/O IRIS INTERNATIONAL, INC.
9158 ETON AVENUE
CHATSWORTH, CA 91311

Corp VP, Pres IRIS Diagnostics

Signatures
/s/ Todd M. Graham, Attorney-in-Fact 11/1/2012
** Signature of Reporting Person Date


Reminder: Report on a separate line for each class of securities beneficially owned directly or indirectly.
* If the form is filed by more than one reporting person, see Instruction 4(b)(v).
** Intentional misstatements or omissions of facts constitute Federal Criminal Violations. See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a).
Note: File three copies of this Form, one of which must be manually signed. If space is insufficient, see Instruction 6 for procedure.
Persons who respond to the collection of information contained in this form are not required to respond unless the form displays a currently valid OMB control number.
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