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This Amendment No. 5 (as defined below) to Schedule 13D (as defined below) is filed by Pillar
Pharmaceuticals I, L.P. (
Pillar I
), Pillar Pharmaceuticals II, L.P. (
Pillar II
), Pillar Pharmaceuticals III, L.P. (
Pillar III
), Pillar Pharmaceuticals IV, L.P. (
Pillar IV
),
Pillar Pharmaceuticals V, L.P. (
Pillar V
), Pillar Pharmaceuticals 6, L.P. (
Pillar 6
), Pillar Invest Corporation (
Pillar GP
), Pillar Partners Foundation, L.P. (
Pillar
Foundation
), Abude Umari and Youssef El Zein (together with Pillar I, Pillar II, Pillar III, Pillar IV, Pillar V, Pillar 6, Pillar Foundation, Pillar GP and Mr. Umari, the
Reporting Persons
). The Reporting Persons
expressly disclaim status as a group for purposes of this Amendment No. 5 to Schedule 13D. Pillar I, Pillar II, Pillar III, Pillar IV, Pillar V, Pillar 6, Pillar Foundation and Pillar GP expressly disclaim beneficial ownership of
any shares of the common stock, par value $0.001 per share (the
Common Stock
) of Idera Pharmaceuticals, Inc., a corporation organized under the laws of the state of Delaware (the
Company
or the
Issuer
), held directly by Messrs. Umari and El Zein, and Messrs. Umari and El Zein expressly disclaim beneficial ownership of any shares of Common Stock held directly by Pillar I, Pillar II, Pillar III, Pillar IV, Pillar V, Pillar
6, Pillar Foundation and indirectly by Pillar GP. Pillar I directly holds 56,100 shares of Common Stock. Pillar II directly holds 40,820 shares of Common Stock. Pillar III directly holds 49,780 shares of Common Stock. Pillar IV directly holds 10,000
shares of Common Stock. Pillar V directly holds 105,000 shares of Common Stock. Pillar 6 directly holds 1,392,259 shares of Common Stock. Pillar Foundation directly holds 1,684,494 shares of Common Stock. Mr. El Zein directly holds 6,724 shares
of Common Stock and 33,125 options to buy shares of Common Stock (exercisable within 60 days of the Transaction Date). Mr. Umari directly holds 39, 922 shares of Common Stock. On July 22, 2019, Pillar GP terminated the advisory
agreement between Pillar GP and Participations Besancon (
Besancon
). As a result, Pillar GP no longer exercises discretionary authority over shares held by Besancon. Accordingly, the 3,418,224 shares of Common Stock reported above
represent 12.2% of the 28,008,037 shares of Common Stock outstanding as of the consummation of the transactions described in Items 4 & 5 below.
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