FORM 4
[ X ] Check this box if no longer subject to Section 16. Form 4 or Form 5 obligations may continue. See Instruction 1(b).         
UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549

STATEMENT OF CHANGES IN BENEFICIAL OWNERSHIP OF SECURITIES
                                                                                  
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Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934 or Section 30(h) of the Investment Company Act of 1940
                      

1. Name and Address of Reporting Person *

BAKER FELIX 		2. Issuer Name and Ticker or Trading Symbol

SYNAGEVA BIOPHARMA CORP [ GEVA ] 		5. Relationship of Reporting Person(s) to Issuer (Check all applicable)

_____ Director                      _____ 10% Owner
_____ Officer (give title below)      __ X __ Other (specify below)
Former 10% owner and Director
(Last)          (First)          (Middle)

667 MADISON AVENUE, 21ST FLOOR 		3. Date of Earliest Transaction (MM/DD/YYYY)

6/22/2015
(Street)

NEW YORK, NY US 10065
(City)        (State)        (Zip)
4. If Amendment, Date Original Filed (MM/DD/YYYY)

 
6. Individual or Joint/Group Filing (Check Applicable Line)

___ Form filed by One Reporting Person
_ X _ Form filed by More than One Reporting Person

Table I - Non-Derivative Securities Acquired, Disposed of, or Beneficially Owned
1.Title of Security
(Instr. 3) 		2. Trans. Date 2A. Deemed Execution Date, if any 3. Trans. Code
(Instr. 8) 		4. Securities Acquired (A) or Disposed of (D)
(Instr. 3, 4 and 5) 		5. Amount of Securities Beneficially Owned Following Reported Transaction(s)
(Instr. 3 and 4) 		6. Ownership Form: Direct (D) or Indirect (I) (Instr. 4) 7. Nature of Indirect Beneficial Ownership (Instr. 4)
Code V Amount (A) or (D) Price
Comon Stock   6/22/2015     D    200526   (1) D   (2) 0   D    
Comon Stock   6/22/2015     D    143462   D   (2) 0   I   See Footnotes   (3) (11)
Comon Stock   6/22/2015     D    12250   D   (2) 0   I   See Footnotes   (4) (11)
Comon Stock   6/22/2015     D    12250   D   (2) 0   I   See Footnotes   (5) (11)
Comon Stock   6/22/2015     D    12250   D   (2) 0   I   See Footnotes   (6) (11)
Comon Stock   6/22/2015     D    680187   D   (2) 0   I   See Footnotes   (7) (11)
Comon Stock   6/22/2015     D    12250   D   (2) 0   I   See Footnotes   (8) (11)
Comon Stock   6/22/2015     D    12250   D   (2) 0   I   See Footnotes   (9) (11)
Comon Stock   6/22/2015     D    9184771   D   (2) 0   I   See Footnotes   (10) (11)

Table II - Derivative Securities Beneficially Owned ( e.g. , puts, calls, warrants, options, convertible securities)
1. Title of Derivate Security
(Instr. 3) 		2. Conversion or Exercise Price of Derivative Security 3. Trans. Date 3A. Deemed Execution Date, if any 4. Trans. Code
(Instr. 8) 		5. Number of Derivative Securities Acquired (A) or Disposed of (D)
(Instr. 3, 4 and 5) 		6. Date Exercisable and Expiration Date 7. Title and Amount of Securities Underlying Derivative Security
(Instr. 3 and 4) 		8. Price of Derivative Security
(Instr. 5) 		9. Number of derivative Securities Beneficially Owned Following Reported Transaction(s) (Instr. 4) 10. Ownership Form of Derivative Security: Direct (D) or Indirect (I) (Instr. 4) 11. Nature of Indirect Beneficial Ownership (Instr. 4)
Code V (A) (D) Date Exercisable Expiration Date Title Amount or Number of Shares
Non-Qualified Stock Option (right to buy)   $11.35   6/22/2015     D         3000    9/22/2011   9/22/2020   Common Stock   3000     (12) 0   I   See Footnote   (13)
Non-Qualified Stock Option (right to buy)   $10.1   6/22/2015     D         2750    7/21/2010   7/21/2019   Common Stock   2750     (12) 0   I   See Footnote   (13)
Non-Qualified Stock Option (right to buy)   $20.6   6/22/2015     D         2750    6/26/2009   6/26/2018   Common Stock   2750     (12) 0   I   See Footnote   (13)
Non-Qualified Stock Option (right to buy)   $25   6/22/2015     D         2750    8/14/2008   8/14/2017   Common Stock   2750     (12) 0   I   See Footnote   (13)
Non-Qualified Stock Option (right to buy)   $33.7   6/22/2015     D         2250    8/9/2007   8/9/2016   Common Stock   2250     (12) 0   I   See Footnote   (13)
Non-Qualified Stock Option (right to buy)   $52.85   6/22/2015     D         2250    8/9/2006   8/9/2015   Common Stock   2250     (12) 0   I   See Footnote   (13)
Non-Qualified Stock Option (right to buy)   $80.35   6/22/2015     D         7500    6/4/2015   6/4/2024   Common Stock   7500     (12) 0   I   See Footnote   (13)
Non-Qualified Stock Option (right to buy)   $40.32   6/22/2015     D         7500    6/6/2013   6/5/2023   Common Stock   7500     (12) 0   I   See Footnote   (13)
Non-Qualified Stock Option (right to buy)   $40.74   6/22/2015     D         7500    6/27/2012   6/27/2022   Common Stock   7500     (12) 0   I   See Footnote   (13)
Non-Qualified Stock Option (right to buy)   $23   6/22/2015     D         15000      (16) 12/19/2021   Common Stock   15000     (12) 0   I   See Footnote   (13)
Non-Qualified Stock Option (right to buy)   $11.35   6/22/2015     D         3000    9/22/2011   9/22/2020   Common Stock   3000     (12) 0   I   See Footnote   (14)
Non-Qualified Stock Option (right to buy)   $10.1   6/22/2015     D         2500    7/21/2010   7/21/2019   Common Stock   2500     (12) 0   I   See Footnote   (14)
Non-Qualified Stock Option (right to buy)   $20.6   6/22/2015     D         2500    6/26/2009   6/26/2018   Common Stock   2500     (12) 0   I   See Footnote   (14)
Non-Qualified Stock Option (right to buy)   $25   6/22/2015     D         2500    8/14/2008   8/14/2017   Common Stock   2500     (12) 0   I   See Footnote   (14)
Non-Qualified Stock Option (right to buy)   $33.7   6/22/2015     D         2250    8/9/2007   8/9/2016   Common Stock   2250     (12) 0   I   See Footnote   (14)
Non-Qualified Stock Option (right to buy)   $52.85   6/22/2015     D         2250    8/9/2006   8/9/2015   Common Stock   2250     (12) 0   I   See Footnote   (14)
Non-Qualified Stock Option (right to buy)   $80.35   6/4/2014     D         7500    6/4/2015   6/4/2024   Common Stock   7500     (12) 0   I   See Footnote   (15)
Non-Qualified Stock Option (right to buy)   $40.32   6/6/2013     D         7500    6/6/2013   6/5/2023   Common Stock   7500     (12) 0   I   See Footnote   (15)
Non-Qualified Stock Option (right to buy)   $40.74   6/27/2012     D         7500    6/27/2012   6/27/2022   Common Stock   7500     (12) 0   I   See Footnote   (15)
Non-Qualified Stock Option (right to buy)   $23   12/20/2011     D         15000      (16) 12/19/2021   Common Stock   15000     (12) 0   I   See Footnote   (15)

Explanation of Responses:
( 1)  Disposition of 100,003 and 100,523 securities directly held by Felix J. Baker and Julian C. Baker, respectively in connection with the Merger Agreement (as defined below).
( 2)  Disposition of securities in connection with the completion of the acquisition of Synageva Biopharma Corp. (the "Issuer") by Alexion Pharmaceuticals, Inc. pursuant to the Agreement and Plan of Reorganization (the "Merger Agreement") dated May 5, 2015, by and among Alexion Pharmaceuticals, Inc., the Issuer, Merger Sub Inc. and Galaxy Merger Sub LLC. Pursuant to the Merger Agreement the Issuer's common shares were exchanged for $115 in cash and 0.6581 share of Alexion Pharmaceuticals, Inc. common stock. (the "Merger Consideration")
( 3)  Disposition of 143,462 shares of Common Stock of the Issuer pursuant to the Merger Agreement directly held by FBB Associates. Felix J. Baker and Julian C. Baker are the sole partners of FBB Associates. Felix J. Baker disclaims beneficial ownership of the securities held directly by FBB Associates except to the extent of his pecuniary interest therein, and this report shall not be deemed an admission that Felix J. Baker or Julian C. Baker is a beneficial owner of such securities for purposes of Section 16 or any other purpose. Julian C. Baker is filing a Form 4 separately.
( 4)  Disposition of 12,250 shares of Common Stock of the Issuer pursuant to the Merger Agreement directly held by Baker/Tisch Investments, L.P. ("Baker Tisch"), a limited partnership of which the sole general partner is Baker/Tisch Capital, L.P., a limited partnership of which the sole general partner is Baker/Tisch Capital (GP), LLC, due to Baker/Tisch Capital, L.P.'s right to receive an allocation of a portion of the profits from Baker Tisch. As a result of their ownership in Baker/Tisch Capital, L.P. Felix J. Baker and Julian C. Baker may be deemed to have an indirect pecuniary interest in shares of common stock of the Issuer directly held by Baker Tisch.
( 5)  Disposition of 12,250 shares of Common Stock of the Issuer pursuant to the Merger Agreement directly held by Baker Bros. Investments, L.P. ("Baker Bros. Investments I"), a limited partnership of which the sole general partner is Baker Bros. Capital, L.P., a limited partnership of which the sole general partner is Baker Bros. Capital (GP), LLC, due to Baker Bros. Capital, L.P.'s right to receive an allocation of a portion of the profits from Baker Bros. Investments I. As a result of their ownership in Baker Bros. Capital, L.P. Felix J. Baker and Julian C. Baker may be deemed to have an indirect pecuniary interest in shares of common stock of the Issuer directly held by Baker Bros. Investments I.
( 6)  Disposition of 12,250 shares of Common Stock of the Issuer pursuant to the Merger Agreement directly held by Baker Bros. Investments II, L.P. ("Baker Bros. Investments II"), a limited partnership of which the sole general partner is Baker Bros. Capital, L.P., a limited partnership of which the sole general partner is Baker Bros. Capital (GP), LLC, due to Baker Bros. Capital, L.P.'s right to receive an allocation of a portion of the profits from Baker Bros. Investments II. As a result of their ownership in Baker Bros. Capital, L.P. Felix J. Baker and Julian C. Baker may be deemed to have an indirect pecuniary interest in shares of common stock of the Issuer directly held by Baker Bros. Investments II.
( 7)  Disposition of 680,187 shares of Common Stock of the Issuer pursuant to the Merger Agreement directly held by 667, L.P. ("667"), a limited partnership of which the sole general partner is Baker Biotech Capital, L.P., a limited partnership of which the sole general partner is Baker Biotech Capital (GP), LLC, due to Baker Biotech Capital, L.P.'s right to receive an allocation of a portion of the profits from 667. As a result of their ownership in Baker Biotech Capital, L.P. Felix J. Baker and Julian C. Baker may be deemed to have an indirect pecuniary interest in shares of common stock of the Issuer directly held by 667.
( 8)  Disposition of 12,250 shares of Common Stock of the Issuer pursuant to the Merger Agreement directly held by Baker Biotech Fund II(A), L.P. ("Baker Biotech"), a limited partnership of which the sole general partner is Baker Biotech Capital II(A), L.P., a limited partnership of which the sole general partner is Baker Biotech Capital II(A) (GP), LLC, due to Baker Biotech Capital II(A), L.P.'s right to receive an allocation of a portion of the profits from Baker Biotech. As a result of their ownership in Baker Biotech Capital, L.P. Felix J. Baker and Julian C. Baker may be deemed to have an indirect pecuniary interest in shares of common stock of the Issuer directly held by Baker Biotech.
( 9)  Disposition of 12,250 shares of Common Stock of the Issuer pursuant to the Merger Agreement directly held by 14159, L.P. ("14159"), a limited partnership of which the sole general partner is 14159 Capital, L.P., a limited partnership of which the sole general partner is 14159 Capital (GP), LLC, due to 14159 Capital, L.P.'s right to receive an allocation of a portion of the profits from 14159. As a result of their ownership in 14159 Capital, L.P. Felix J. Baker and Julian C. Baker may be deemed to have an indirect pecuniary interest in shares of common stock of the Issuer directly held by 14159.
( 10)  Disposition of 9,184,771 shares of Common Stock of the Issuer pursuant to the Merger Agreement directly held by Baker Brothers Life Sciences, L.P. ("Life Sciences"), a limited partnership of which the sole general partner is Baker Brothers Life Sciences Capital, L.P., a limited partnership of which the sole general partner is Baker Brothers Life Sciences Capital (GP), LLC, due to Baker Brothers Life Sciences Capital, L.P.'s right to receive an allocation of a portion of the profits from Life Sciences. As a result of their ownership in Baker Brothers Life Sciences Capital, L.P. Felix J. Baker and Julian C. Baker may be deemed to have an indirect pecuniary interest in shares of common stock of the Issuer directly held by Life Sciences.
( 11)  Baker Bros. Advisors LP (the "Adviser") serves as the Investment Adviser to Baker Tisch, Baker Bros. Investments I, Baker Bros. Investments II, 667, Baker Biotech, 14159, and Life Sciences (collectively, the "Funds"). In connection with the services provided by the Adviser, the Adviser receives an asset-based management fee that does not confer any pecuniary interest in the securities held by the Funds. Baker Bros. Advisors (GP) LLC (the "Adviser GP") is the Adviser's sole general partner. Julian C. Baker and Felix J. Baker are principals of the Adviser GP. The Adviser has complete and unlimited discretion and authority with respect to the investment and voting power of the securities held by the Funds. The general partners of the Funds relinquished to the Adviser all discretion and authority with respect to the investment and voting power of the securities held by the Funds. Julian C. Baker, Felix J. Baker, the Adviser GP and the Adviser disclaim beneficial ownership of the securities held directly by the Funds except to the extent of their pecuniary interest therein, and this report shall not be deemed an admission that any of Julian C. Baker, Felix J. Baker, the Adviser GP or the Adviser is a beneficial owner of such securities for purposes of Section 16 or any other purpose.
( 12)  Disposition of options pursuant to the Merger Agreement, under which such options became fully vested and cancelled and the holder of such options became entitled to receive amount of cash and number of shares of common stock of Alexion Pharmaceuticals, Inc. equal to : (i) the Merger Consideration multiplied by (ii) a number of shares of common stock equal to (1) $230.00 minus the corresponding per share exercise price of such options, divided by (2) $230.00, with the cash portion of such amount rounded to the nearest cent and with the portion of such amount payable in common stock rounded down to the nearest one thousandth of a shares.
( 13)  Non-qualified stock options ("Stock Options") convertible solely into common shares of the Issuer that were granted to Felix J. Baker. Felix J. Baker served on the Issuer's Board of Directors (the "Board") as a representative of the Funds. Pursuant to the policies of the Adviser, Felix J. Baker does not have any right to any of the Issuer's securities issued as part of his service on the Board and the Funds are entitled to receive all the pecuniary interest in the securities issued. The Funds each own an indirect proportionate pecuniary interest in the Stock Options. Solely as a result of Felix J. Baker's and Julian C. Baker's ownership interest in the general partners of the general partners of the Funds, Felix J. Baker and Julian C. Baker may be deemed to have an indirect pecuniary interest in the stock options (i.e. no direct pecuniary interest).
( 14)  Stock Options convertible solely into common shares of the Issuer that were granted to Julian C. Baker. Julian C. Baker served on the Board as a representative of the Funds. Pursuant to the policies of the Adviser, Julian C. Baker does not have any right to any of the Issuer's securities issued as part of his service on the Board and the Funds are entitled to receive all the pecuniary interest in the securities issued. The Funds each own an indirect proportionate pecuniary interest in the Stock Options. Solely as a result of Felix J. Baker's and Julian C. Baker's ownership interest in the general partners of the general partners of the Funds, Felix J. Baker and Julian C. Baker may be deemed to have an indirect pecuniary interest in the stock options (i.e. no direct pecuniary interest).
( 15)  Stock Options convertible solely into common shares of the Issuer that were granted to Stephen R. Biggar. Stephen R. Bigger, an employee of Baker Bros. Advisors LP served on the Board as a representative of the Funds. Pursuant to the policies of the Adviser, Stephen R. Biggar does not have any right to any of the Issuer's securities issued as part of his service on the Board and the Funds are entitled to receive all the pecuniary interest in the securities issued. The Funds each own an indirect proportionate pecuniary interest in the Stock Options. Solely as a result of Felix J. Baker's and Julian C. Baker's ownership interest in the general partners of the general partners of the Funds, Felix J. Baker and Julian C. Baker may be deemed to have an indirect pecuniary interest in the stock options (i.e. no direct pecuniary interest).
( 16)  1/36 of the shares subject to this option vest and become exercisable on December 2, 2011 and monthly thereafter.

Remarks:
Pursuant to the consummation of the merger, pursuant to the Merger Agreement (as defined in footnote 2) on June 22, 2015 Felix J. Baker tendered his resignation as a director of Synageva Biopharma Corp.

Reporting Owners
Reporting Owner Name / Address
Relationships
Director 10% Owner Officer Other
BAKER FELIX
667 MADISON AVENUE, 21ST FLOOR
NEW YORK, NY US 10065


Former 10% owner and Director
Baker Bros. Advisors (GP) LLC
667 MADISION AVENUE 21ST FLOOR
NEW YORK, NY US 10065


Former 10% owner and Director
BAKER BROS. ADVISORS LP
667 MADISON AVENUE, 21ST FLOOR
NEW YORK, NY US 10065


Former 10% owner and Director
BAKER JULIAN
667 MADISON AVENUE, 21ST FLOOR
NEW YORK, NY US 10065


Former 10% owner and Director
Baker Brothers Life Sciences LP
667 MADISON AVENUE, 21ST FLOOR
NEW YORK, NY US 10065


Former 10% owner and Director
14159, L.P.
667 MADISION AVENUE, 21ST FLOOR
NEW YORK, NY US 10065


Former 10% owner and Director
667, L.P.
667 MADISON AVENUE 21ST FLOOR
NEW YORK, NY US 10065


Former 10% owner and Director
Baker/Tisch Investments, LP
667 MADISON AVENUE, 21ST FLOOR
NEW YORK, NY US 10065


Former 10% owner and Director
Baker Bros. Investments, L.P.
667 MADISON AVENUE
NEW YORK, NY US 10065


Former 10% owner and Director
Baker Bros. Investments II, L.P.
667 MADISON AVENUE 21ST FLOOR
NEW YORK, NY US 10065


Former 10% owner and Director

Signatures
/s/ Felix J. Baker 6/23/2015
** Signature of Reporting Person Date

Baker Bros. Advisors (GP) LLC Name: Scott L. Lessing, Title: President /s/ Scott L. Lessing 6/23/2015
** Signature of Reporting Person Date

Baker Bros. Advisors LP Name: Scott L. Lessing, Title: President /s/ Scott L. Lessing 6/23/2015
** Signature of Reporting Person Date

/s/ Julian C. Baker 6/23/2015
** Signature of Reporting Person Date

Baker Bros. Advisors LP, Mgmt. Co. and Inv. Adviser to Baker Brothers Life Sciences, L.P., pursuant to authority granted by Baker Brothers Life Sciences Capital, L.P., GP Name: Scott L. Lessing, Title: President /s/ Scott L. Lessing 6/23/2015
** Signature of Reporting Person Date

Baker Bros. Advisors LP, Mgmt. Co. and Inv. Adviser to 14159, L.P., pursuant to authority granted by 14159 Capital, L.P., GP to 14159, L.P. Name: Scott L. Lessing, Title: President /s/ Scott L. Lessing 6/23/2015
** Signature of Reporting Person Date

Baker Bros. Advisors LP, Mgmt. Co. and Inv. Adviser to 667, L.P., pursuant to authority granted by Baker Biotech Capital, L.P., GP to 667, L.P. Name: Scott L. Lessing Title: President /s/ 6/23/2015
** Signature of Reporting Person Date

Baker Bros. Advisors LP, Mgmt. Co. and Inv. Adviser to Baker Tisch Investments, L.P. , pursuant to authority granted by Baker Tisch Capital, L.P., GP to Baker Tisch Investments, L.P. Name: Scott L. Lessing Title: President /s/ 6/23/2015
** Signature of Reporting Person Date

Baker Bros. Advisors LP, Mgmt. Co. and Inv. Adviser to Baker Bros. Investments, L.P., pursuant to authority granted by Baker Bros. Capital, L.P., GP to Baker Bros. Investments, L.P. Name: Scott L. Lessing Title: President /s/ 6/23/2015
** Signature of Reporting Person Date

Baker Bros. Advisors LP, Mgmt. Co. and Inv. Adviser to Baker Bros. Investments II, L.P., pursuant to authority granted by Baker Bros. Capital, L.P., GP to Baker Bros. Investments II, L.P. Name: Scott L. Lessing Title: President /s/ 6/23/2015
** Signature of Reporting Person Date


Reminder: Report on a separate line for each class of securities beneficially owned directly or indirectly.
* If the form is filed by more than one reporting person, see Instruction 4(b)(v).
** Intentional misstatements or omissions of facts constitute Federal Criminal Violations. See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a).
Note: File three copies of this Form, one of which must be manually signed. If space is insufficient, see Instruction 6 for procedure.
Persons who respond to the collection of information contained in this form are not required to respond unless the form displays a currently valid OMB control number.
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