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Compass Therapeutics Inc

Compass Therapeutics Inc (CMPX)

1.17
0.06
(5.41%)
Closed June 17 4:00PM
1.18
0.01
( 0.85% )
Pre Market: 7:19AM

Your Hub for Real-Time streaming quotes, Ideas and Live Discussions

Key stats and details

Current Price
1.18
Bid
1.08
Ask
1.19
Volume
100
0.00 Day's Range 0.00
1.06 52 Week Range 3.45
Market Cap
Previous Close
1.17
Open
-
Last Trade Time
07:19:36
Financial Volume
-
VWAP
-
Average Volume (3m)
301,444
Shares Outstanding
127,486,326
Dividend Yield
-
PE Ratio
-3.51
Earnings Per Share (EPS)
-0.33
Revenue
-
Net Profit
-42.49M

About Compass Therapeutics Inc

Compass Therapeutics Inc is a clinical-stage biopharmaceutical company that develops proprietary antibody therapeutics intended to engage the immune system to treat both solid tumors and hematological malignancies. It is engaged in drug discovery by leveraging its proprietary antibody discovery engi... Compass Therapeutics Inc is a clinical-stage biopharmaceutical company that develops proprietary antibody therapeutics intended to engage the immune system to treat both solid tumors and hematological malignancies. It is engaged in drug discovery by leveraging its proprietary antibody discovery engine to broadly drug the immune system and identify optimal combinations empirically. Through StitchMabs and common light chain platforms, these combinatorial insights can be rapidly translated into tailored bispecifics with monoclonal-like manufacturability. The company has drugged over 40 immune targets and generated a diverse pipeline of monoclonal and multispecific therapeutic candidates with potential to transform care for patients with cancer or autoimmune diseases. Show more

Sector
Biological Pds,ex Diagnstics
Industry
Biological Pds,ex Diagnstics
Headquarters
Wilmington, Delaware, USA
Founded
1970
Compass Therapeutics Inc is listed in the Biological Pds,ex Diagnstics sector of the NASDAQ with ticker CMPX. The last closing price for Compass Therapeutics was $1.17. Over the last year, Compass Therapeutics shares have traded in a share price range of $ 1.06 to $ 3.45.

Compass Therapeutics currently has 127,486,326 shares outstanding. The market capitalization of Compass Therapeutics is $149.16 million. Compass Therapeutics has a price to earnings ratio (PE ratio) of -3.51.

CMPX Latest News

Compass Therapeutics to Participate in the Jefferies Global Healthcare Conference

BOSTON, May 30, 2024 (GLOBE NEWSWIRE) -- Compass Therapeutics, Inc. (Nasdaq: CMPX), a clinical-stage, oncology-focused biopharmaceutical company developing proprietary antibody-based...

Compass Therapeutics Announces CEO Transition

BOSTON, May 28, 2024 (GLOBE NEWSWIRE) -- Compass Therapeutics, Inc. (Nasdaq: CMPX), a clinical-stage, oncology-focused biopharmaceutical company developing proprietary antibody-based...

Compass Therapeutics to Present Phase 1 Data for CTX-471, A Novel CD137 Agonist Antibody, Demonstrating Anti-Tumor Activity in Patients Who Have Progressed on Approved PD-1 or PD-L1 Inhibitors at the American Society of Clinical Oncology (ASCO) Annual Meet

CTX-471, a novel anti-CD137 agonist antibody, demonstrated anti-tumor activity in the Company’s Phase 1 Dose Escalation and Dose Expansion, first-in-human monotherapy study in patients with...

Compass Therapeutics to Participate in the H.C. Wainwright 2nd Annual BioConnect Investor Conference

BOSTON, May 14, 2024 (GLOBE NEWSWIRE) --  Compass Therapeutics, Inc. (Nasdaq: CMPX), a clinical-stage, oncology-focused biopharmaceutical company developing proprietary antibody-based...

Compass Therapeutics Reports 2024 First Quarter Financial Results and Provides Corporate Update

Received FDA Fast Track Designation for the investigation of CTX-009 in combination with paclitaxel for the treatment of patients with metastatic or locally advanced biliary tract tumors...

Compass Therapeutics Receives FDA Fast Track Designation for the Investigation of CTX-009 in Combination with Paclitaxel for the Treatment of Patients with Metastatic or Locally Advanced Biliary Tract Tumors That Have Been Previously Treated

CTX-009, the Company’s bispecific DLL4/VEGF-A antibody, in combination with paclitaxel, has shown promising clinical responses in patients with advanced biliary tract cancer (BTC) in its Phase 2...

PeriodChangeChange %OpenHighLowAvg. Daily VolVWAP
1-0.03-2.479338842981.211.291.065192331.17693556CS
4-0.42-26.251.61.61691.062932421.28401692CS
12-0.94-44.33962264152.122.2091.063014441.52178685CS
26-0.43-26.70807453421.612.341.064174631.6540877CS
52-1.86-61.18421052633.043.451.064249012.06485024CS
156-2.92-71.21951219514.15.651.063115362.60337681CS
260-2.92-71.21951219514.15.651.063115362.60337681CS

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CMPX Discussion

View Posts
Monksdream Monksdream 3 months ago
CMPX 10Q due 3/25
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Monksdream Monksdream 3 months ago
CMPX 10Q due 3/18
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glenn1919 glenn1919 3 months ago
CMPX....................................https://stockcharts.com/h-sc/ui?s=CMPX&p=W&b=5&g=0&id=p86431144783
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Monksdream Monksdream 3 months ago
Cant say offhand
Read the latest 10Q
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stockweiser stockweiser 3 months ago
Do you know there current cash on hand?
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Monksdream Monksdream 3 months ago
CMPX 10Q due March 11
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Monksdream Monksdream 5 months ago
CMPX new 52=week low
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Monksdream Monksdream 7 months ago
CMPX new 52 week low
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Monksdream Monksdream 9 months ago
CMPX under $2
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Copilotdog Copilotdog 9 months ago
Solid company
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Mktman2024 Mktman2024 1 year ago
Compass to review latest phase 2 progress with CTX 009 and other items at ASCO Jan 19-21.
Company moving slowly into the spotlight.
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Mktman2024 Mktman2024 2 years ago
Reminder CMPX is Compass Therapeutics ,,,EF Hutton new target 10
targets range from 8-15
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Mktman2024 Mktman2024 2 years ago
https://www.streetinsider.com/Corporate+News/Compass+Therapeutics%2C+Inc+%28CMPX%29+doses+first+patient+in+Phase+1b+CTX-471+combo+with+KEYTRUDA/20920046.html

now were talking!!
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Mktman2024 Mktman2024 2 years ago
amazing no one posts on any CMPX boards except twitter ...and even then crickets
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Mktman2024 Mktman2024 2 years ago
The proper company name associated with CMPX symbol
Compass Therapeutics . If one were to review the 6 or 7 bispecifics currently approved for cancer, the efficacy of CTX 009 , CTX 471 and CTX 8371 in early trials is astounding...with a very unique Moa...still not understood by most analysts. It clearly warrants a collaboration with Merck on 471 and potentially many others. The stitchmab they have developed is a real game changing technology optimizing the best suitable mab combinations , along with Taxol, Keytruda and others ...supercharging the efficacy of current drug therapies. This stock has multiple undervalued assets.
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Mktman2024 Mktman2024 2 years ago
Do you think they like their company ...a little??

Compass Therapeutics, Inc. Insider Trading Activity (benzinga.com)
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NO birds Allowed NO birds Allowed 2 years ago
dude WTF!!!! another ALLM
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NO birds Allowed NO birds Allowed 2 years ago
is eh CEO still buying?
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Mktman2024 Mktman2024 2 years ago
The relative outperformance continues stock sits at 3.05 .Phase 2/3 in US will begin Q4 ...more oustanding data to follow. 3X is easy with this one.
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Mktman2024 Mktman2024 2 years ago
CEO continues to buy stock buys another 15000 filed 8/17 owns over 5.3 million shares

https://ih.advfn.com/stock-market/NASDAQ/compass-therapeutics-CMPX/stock-news/88862025/statement-of-changes-in-beneficial-ownership-4
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Mktman2024 Mktman2024 2 years ago
Now we're talking !! 3.00 then 3.27 news might be coming fairly soon
New data plus CTX 009 US trial enrollment . winner..
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Mktman2024 Mktman2024 2 years ago
Could the rocket be on the launching pad ?? volume building nicely for a name thats still under the radar.
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Mktman2024 Mktman2024 2 years ago
Awaiting further data on CTX 009 and the expansion of trials to the US
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NO birds Allowed NO birds Allowed 2 years ago
I forgot to ask, have you or brooklyn participated in this last raise?I am waiting for the next one at .05
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NO birds Allowed NO birds Allowed 2 years ago
you must have guessed by now that we have a mutual friend involved in both of these stocks
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NO birds Allowed NO birds Allowed 2 years ago
hello old friend, this looks so much better than the other
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Mktman2024 Mktman2024 2 years ago
To present at Jefferies H/C conf. june 9th...will they join the recommended list there too?
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Mktman2024 Mktman2024 2 years ago
CEO buys 60,000 more on 5/28 owns 5.2 +million
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Mktman2024 Mktman2024 2 years ago
Still amazed no posts on any stock msg boards Its under the retail radar so far while its 67% institutionally owned 5 analysts cover targets 9 11 15 to name a few.....add to this recent institutional buying as well as insider buys...Founders came from Orbimed. I'm all in.
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Mktman2024 Mktman2024 2 years ago
B of A health conf went great . more exposure to this company with some amazing drug discovery anti tumor tech. Waiting to see more coverage upgrades and target price increases .Major board members buying more at 2.50...company still well under the radar .My number one pick for 2022-2023. potential 5 to 10 X from here. Targets still way too low.
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Mktman2024 Mktman2024 2 years ago
More insider buys and nice names involved.Love this sleeper
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Mktman2024 Mktman2024 2 years ago
I like this stock .10 ct downside 5 to 7 dollar upside. Two legal Jds join the board .company actively seeking merger or JV partners ...a no brainer. targets range from 5 to 11 a share ...high institutional ownership by respected names.Guess Im the first to post here...in quite some time early is better than late.
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wiredawg wiredawg 3 years ago
4 previous posts (to qualify as a board moderator).

E-trade Data, CoB 9 Nov 2021:
- $3.76 Share price
- 98.0M Shares Outstanding
- $368.6M Market Cap
- 282,952 Avg Volume (10 day)
- 2.01-11.00 52 Week Range
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wiredawg wiredawg 3 years ago
https://www.compasstherapeutics.com/press-releases/compass-therapeutics-to-commence-trading-on-the-otcqb-venture-market-under-the-symbol-cmpx/

Compass Therapeutics to Commence Trading on the OTCQB Venture Market Under the Symbol “CMPX”
BOSTON, Mass., Mar. 4, 2021 — Compass Therapeutics, Inc. (OTCQB: CMPX), a clinical-stage biotechnology company developing proprietary antibody therapeutics intended to engage the immune system to treat both solid tumors and hematological malignancies, announced today that shares of the company’s common stock have been cleared for trading on the OTCQB Venture Market in the United States. The Company’s shares will trade under the ticker symbol “CMPX”, effective at the market open on March 5, 2021.

About Compass Therapeutics

Compass Therapeutics is a clinical-stage biopharmaceutical company developing proprietary antibody therapeutics intended to engage the immune system to treat both solid tumors and hematologic malignancies. Compass is leveraging its proprietary StitchMabs™ and common light-chain based multispecific platforms to empirically identify multispecifics and combinations of antibody therapeutics that synergistically modulate key nodes in the immune system. The company’s lead product candidate, CTX-471, is a fully human agonistic antibody of CD137, and is currently being evaluated in a Phase 1 study in patients who were previously treated with PD-1/PD-L1 checkpoint inhibitors and who subsequently relapsed or progressed after a period of stable disease. The company’s offices and labs are located in Boston, MA. Its website is at www.compasstherapeutics.com.

Forward-Looking Statements

This press release contains forward-looking statements. Statements in this press release that are not purely historical are forward-looking statements. Such forward-looking statements include, among other things, the commencement of trading on OTCQB, references to our product candidates and the development and therapeutic potential thereof, our technologies for identifying additional product candidates, and our business and development plans. Actual results could differ from those projected in any forward-looking statements due to numerous factors. Such factors include, among others, our ability to raise the additional funding we will need to continue to pursue our business and product development plans, the inherent uncertainties associated with developing product candidates and operating as a development stage company, our ability to identify additional product candidates for development, our ability to develop, complete clinical trials for, obtain approvals for and commercialize any of our product candidates, and competition in the industry in which we operate and market conditions. These forward-looking statements are made as of the date of this press release, and Compass assumes no obligation to update the forward-looking statements, or to update the reasons why actual results could differ from those projected in the forward-looking statements, except as required by law. Investors should consult all of the information set forth herein and should also refer to the risk factor disclosure set forth in the reports and other documents we file with the SEC available at www.sec.gov, including without limitation our Form 10-Q for the quarter ended September 30, 2020, and our subsequent filings with the SEC.

Contacts
Investor Contact
Compass Therapeutics, Inc.
Vered Bisker-Leib, President & Chief Operating Officer
ir@compasstherapeutics.com

Media Contact
media@compasstherapeutics.com
617-500-8099

© 2021 Compass Therapeutics, Inc.Terms & ConditionsPrivacy Policy
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wiredawg wiredawg 3 years ago
https://www.compasstherapeutics.com/press-releases/compass-reports-the-advancement-of-ctx-009-a-bispecific-antibody-to-phase-2a-development-in-patients-with-biliary-tract-cancers-btc-and-the-clearance-of-a-key-clinical-hurdle/

Compass Reports the Advancement of CTX-009, a Bispecific Antibody, to Phase 2a Development in Patients with Biliary Tract Cancers (BTC), and the Clearance of a Key Clinical Hurdle
Phase 2a study was initiated by Handok Pharmaceuticals in Q1 2021 in patients with Biliary Tract Cancers (cholangiocarcinoma).
Enrollment in the first part of the study has been completed and the criteria to advance to the second part of the study have been met.
Notably, five partial responses have already been observed among the first 17 patients evaluated leading to a preliminary overall response rate of 29% (ORR=29%), and all patients evaluated have had stable disease or better with a decline in tumor burden observed in 16 of the 17 patients leading to a Clinical Benefit Rate of 100% (CBR=100%).
Compass plans to submit an Investigational New Drug (IND) application to the United States Food and Drug Administration (FDA) this quarter, and subject to the IND clearance with the FDA, to initiate a Phase 2 study in Q2 2022.
BOSTON, November 1st, 2021 – Compass Therapeutics, Inc. (OTC:CMPX) today provided an update on the clinical development of CTX-009 (also known as ABL001), a dual anti-angiogenic bispecific antibody targeting DLL4 and VEGF-A.

A Phase 2a study for CTX-009 in combination with paclitaxel was initiated by Handok Pharmaceuticals, Inc. (KOSDAQ: 002390) in Q1 2021 in patients with BTC and the enrollment in the first part of the study has been completed. The study has been enrolling patients who have unresectable advanced, metastatic, or relapsed BTC’s who have received one or two prior systemic therapies. The Phase 2a design was informed by the CTX-009 Phase 1b study, where CTX-009 in combination with either paclitaxel or irinotecan led to an overall response rate of 23.5% and a clinical benefit rate of 76.5%, including two confirmed and durable partial responses among four patients with advanced cholangiocarcinoma (clinicaltrials.gov Identifier: NCT04492033).

The Phase 2a study utilizes a Simon Two-Stage adaptive design where the criteria to advance to the second stage of the study is three or more partial responses observed in 21 patients. So far, there have been five partial responses observed among the first 17 patients evaluated, which is an overall response rate of 29%, and accordingly, the criteria to advance to the second part of the study has been met. In the second part of the Phase 2a study, 45 additional patients will be enrolled. The preliminary adverse event profile of CTX-009 in this Phase 2a study is consistent with prior studies of CTX-009 with hypertension and neutropenia being the most common events related to CTX-009 and paclitaxel, respectively. Handok initiated the study in Q1 2021 at four leading medical centers in South Korea. Compass plans on submitting an IND for CTX-009 in the United States later this quarter and subject to the IND going into effect with the FDA, plans on initiating a Phase 2 study in the United States in Q2 2022.

“Patients with cholangiocarcinoma have limited treatment options following front line combination chemotherapy. In the Phase 1b and Phase 2a studies, we have seen a total of seven partial responses in 21 total patients evaluated. Impressively, there have been measurable tumor declines in 19 of the 21 advanced patients treated across both studies. We are looking forward to filing our IND in the United States this quarter and pursuing the global development of CTX-009,” said Thomas Schuetz, M.D., Ph.D., CEO and scientific founder of Compass. Compass holds the global rights to CTX-009 with the exception of South Korea rights, which are held by Handok, and China rights, which were out-licensed to Elpiscience Biopharma.

About CTX-009
CTX-009 is a bispecific antibody that simultaneously blocks Delta-like ligand 4/Notch (DLL4) and vascular endothelial growth factor A (VEGF-A) signaling pathways, which are critical to angiogenesis and tumor vascularization. Preclinical and early clinical data of CTX-009 suggest that blockade of both pathways provides robust anti-tumor activity across several solid tumors, including colorectal, gastric, cholangiocarcinoma, pancreatic and non-small cell lung cancer. Partial responses to CTX-009 as a monotherapy have been observed in heavily pre-treated cancer patients, who were resistant to currently approved anti-VEGF therapies. CTX-009 has completed a Phase 1 monotherapy dose escalation and dose expansion study. Phase 1b and Phase 2a combination studies are ongoing.

About Compass Therapeutics
Compass Therapeutics, Inc. is a clinical-stage, oncology-focused biopharmaceutical company developing proprietary antibody-based therapeutics to treat multiple human diseases. Compass’s scientific focus is on the relationship between angiogenesis, the immune system, and tumor growth. The company pipeline of novel product candidates is designed to target multiple critical biological pathways required for an effective anti-tumor response. These include modulation of the microvasculature via angiogenesis-targeted agents, induction of a potent immune response via activators on effector cells in the tumor microenvironment, and alleviation of immunosuppressive mechanisms used by tumors to evade immune surveillance. Compass plans to advance its product candidates through clinical development as both standalone therapies and in combination with proprietary pipeline antibodies based on supportive clinical and nonclinical data. The company was founded in 2014 and is headquartered in Boston, Massachusetts.

Forward-Looking Statements
This press release contains forward-looking statements. Statements in this press release that are not purely historical are forward-looking statements. Such forward-looking statements include, among other things, references to Compass’s product candidate, CTX-009, its development, regulatory plans with respect thereto and therapeutic potential thereof. Actual results could differ from those projected in any forward-looking statements due to numerous factors. Such factors include, among others, Compass’s ability to raise the additional funding it will need to continue to pursue our business and product development plans, the inherent uncertainties associated with developing product candidates and operating as a development stage company, Compass’s ability to identify additional product candidates for development, Compass’s ability to develop, complete clinical trials for, obtain approvals for and commercialize any of its product candidates, competition in the industry in which Compass operates and market conditions. These forward-looking statements are made as of the date of this press release, and Compass assumes no obligation to update the forward-looking statements, or to update the reasons why actual results could differ from those projected in the forward-looking statements, except as required by law. Investors should consult all the information set forth herein and should also refer to the risk factor disclosure set forth in the reports and other documents Compass files with the SEC available at www.sec.gov.

COMPASS Contacts
Investor Inquiries
Vered Bisker-Leib
info@compasstherapeutics.com
+1 617 500 8099

Media Inquiries
Anna Gifford
media@compasstherapeutics.com
+1 617 500 8099

© 2021 Compass Therapeutics, Inc.Terms & ConditionsPrivacy Policy
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wiredawg wiredawg 3 years ago
https://www.compasstherapeutics.com/press-releases/compass-therapeutics-announces-pricing-of-approximately-125-million-public-offering-of-common-stock-and-uplisting-to-nasdaq-capital-market/

Compass Therapeutics Announces Pricing of Approximately $125 Million Public Offering of Common Stock and Uplisting to Nasdaq Capital Market
Boston, November 1, 2021 — Compass Therapeutics, Inc. (the “Company”), a clinical-stage biopharmaceutical company developing proprietary antibody-based therapeutics to treat cancer, today announced that it has priced an underwritten public offering to sell 35,715,000 shares of common stock at a public offering price of $3.50 per share. All of the shares of common stock are being offered by the Company. In addition, the Company has granted the underwriters a 30-day option to purchase up to an additional 5,357,250 shares of common stock at the public offering price, less the underwriting discount. In connection with the offering, the Company also announced that its common stock will begin trading on the Nasdaq Capital Market under the symbol “CMPX” at the opening of trading on November 2, 2021, following its previously announced approval to list its common stock on the Nasdaq Capital Market. The gross proceeds to the Company from the public offering, before deducting underwriting discounts and commissions and estimated offering expenses, are expected to be approximately $125.0 million.

The offering is expected to close on November 4, 2021, subject to customary closing conditions. The Company intends to use the net proceeds from the public offering, together with its existing cash and cash equivalents, for funding of ongoing operations including clinical trials for the programs noted in the preliminary prospectus supplement, which may change based on clinical and preclinical results.

SVB Leerink acted as book-running manager for the offering. Raymond James & Associates, Inc., Wedbush Securities and H.C. Wainwright & Co. acted as passive book-running managers and The Benchmark Company and Roth Capital Partners acted as co-managers for the offering.

The securities described above are being offered by the Company pursuant to a shelf registration statement on Form S-3 (No. 333-257821) that was declared effective by the Securities and Exchange Commission on July 20, 2021. A preliminary prospectus supplement and accompanying prospectus relating to the offering were filed with the SEC and are available on the SEC’s website located at www.sec.gov. A final prospectus supplement and accompanying prospectus describing the terms of the offering will be filed with the SEC and will be available on the SEC’s website. Copies of the final prospectus supplement and the accompanying prospectus relating to this offering may also be obtained, when available, from SVB Leerink LLC, Attention: Syndicate Department, 53 State Street, 40th Floor, Boston, MA 02109, by telephone at (800) 808-7525, ext. 6105, or by email at syndicate@svbleerink.com.

This press release shall not constitute an offer to sell or the solicitation of an offer to buy, nor shall there be any sale of these securities in jurisdiction in which such an offer, solicitation or sale would be unlawful prior to registration or qualification under the securities laws of any such jurisdiction. Any offer, if at all, will be made only by means of the prospectus supplement and accompanying prospectus forming a part of the effective registration statement.

About Compass Therapeutics
Compass Therapeutics, Inc. is a clinical-stage, oncology-focused biopharmaceutical company developing proprietary antibody-based therapeutics to treat multiple human diseases. Compass’s scientific focus is on the relationship between angiogenesis, the immune system, and tumor growth. The company pipeline of novel product candidates is designed to target multiple critical biological pathways required for an effective anti-tumor response. These include modulation of the microvasculature via angiogenesis-targeted agents, induction of a potent immune response via activators on effector cells in the tumor microenvironment, and alleviation of immunosuppressive mechanisms used by tumors to evade immune surveillance. Compass plans to advance its product candidates through clinical development as both standalone therapies and in combination with proprietary pipeline antibodies based on supportive clinical and nonclinical data. The company was founded in 2014 and is headquartered in Boston, Massachusetts.

Forward-Looking Statements
This press release contains forward-looking statements. Statements in this press release that are not purely historical are forward-looking statements. Such forward-looking statements include, among other things, statements regarding the completion of the proposed offering and the expected use of proceeds from the proposed offering, references to the Company’s product candidate, CTX-009, its development, regulatory plans with respect thereto and therapeutic potential thereof. Actual results could differ from those projected in any forward-looking statements due to numerous factors. Such factors include, among others, the Company’s ability to raise the additional funding it will need to continue to pursue its business and product development plans, the inherent uncertainties associated with developing product candidates and operating as a development stage company, the Company’s ability to identify additional product candidates for development, the Company’s ability to develop, complete clinical trials for, obtain approvals for and commercialize any of its product candidates, competition in the industry in which the Company operates and market conditions. These forward-looking statements are made as of the date of this press release, and the Company assumes no obligation to update the forward-looking statements, or to update the reasons why actual results could differ from those projected in the forward-looking statements, except as required by law. Investors should consult all the information set forth herein and should also refer to the risk factor disclosure set forth in the reports and other documents the Company files with the SEC available at www.sec.gov.

Investor Contact
Vered Bisker-Leib, President & Chief Operating Officer
ir@compasstherapeutics.com

Media Contact
media@compasstherapeutics.com
617-500-8099
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wiredawg wiredawg 3 years ago
ALRIGHT NOW!!! A first for me to be the very first post. Though, I don't own shares yet, currently tapped out, juggling some other stocks at the moment and trying at the same time attempting to manage the tax implications...fun stuff LOL But on my list to gather some shares in the near future. Interested in their CTX-009 pipeline:

CTX-009 is a bispecific antibody that simultaneously targets Delta-like ligand 4 (DLL4) and vascular endothelial growth factor A (VEGF-A). This next generation angiogenic inhibitor has completed Phase 1 dose escalation and expansion study, and a Phase 1b in combination with chemotherapy is ongoing. As a monotherapy, CTX-009 has demonstrated clinical benefit in heavily pre-treated patients who have progressed after prior VEGF, EGFR, HER2, and PD1/L1-targeted therapies. Multiple, deep clinical responses were observed in patients with advanced colorectal cancer and in patients with gastric cancer. Multiple durable responses were also observed in the ongoing combination study in patients with cholangiocarcinoma and pancreatic cancer.

GLTA
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