Prestigious Klee Family Foundation Prize 2020 Awarded for Outstanding Scientific Work Identifying Patient-Specific Approach a...
May 21 2020 - 8:00AM
Conformis, Inc. (NASDAQ: CFMS) congratulates Dr. Malte Asseln for
winning the prestigious Klee Prize 2020 for his dissertation and
computer-and-image-based workflow on the optimization of knee
implant design - “Morphological and Functional Analysis of the Knee
Joint for Implant Design Optimization.”
As reported in Medizin and Technik on May 6, 2020,
Dr. Asseln’s results show that more knee implant sizes are required
than are currently manufactured by off-the-shelf knee implant
manufacturers, so patient-specific or better-tailored solutions are
a promising approach to increase the 70 percent industry-wide
patient satisfaction with artificial knee joints that he has
observed.
Dr. Asseln concluded that one of the main drivers
of the 30 percent industry-wide dissatisfaction with knee implants
is the design of standard implants, which takes insufficient
account of patient-specific biomechanics.
“I am always pleased to see third-party scientific
research validate my belief in the inherent superiority of the
patient-specific knee implant design approach over standard,
off-the-shelf knee design to eliminate joint pain relief,” said
Mark Augusti, President and CEO of Conformis, Inc. “Congratulations
to Dr. Asseln!”
As part of his analysis, Dr. Asseln developed
methods for generating parameterized surface models of articular
surfaces to enable systematic shape variations. He also developed a
patient-specific biomechanical simulation model of the lower
extremity and an experimental bench test to analyze the
relationship between design parameters and knee function. Further,
he used the outer geometric dimensions of the knee joint to
calculate a sufficient number of implant sizes.
For his morphological analysis of the natural knee
joint, Dr. Asseln built up a comprehensive database with geometric
features and evaluated them. He used a database of 831 patient
records, from which 59 geometric features were extracted.
Most traits showed statistically significant gender
differences. After Dr. Asseln classified and normalized the
features according to the direction of their measurement (i.e.
width and depth), it became apparent that, after normalization,
there were large inter-individual deviations, which indicates that
patient-specific design solutions would be the only way to
accommodate for these differences.
About The Klee Prize and the VDE
Association
The Klee Prize is an annual prize awarded by the
German Society for Biomedical Engineering at the VDE Association
and the Klee Family Foundation. The prize is worth 5,000 euros and
is awarded in a competition for outstanding scientific work in
biomedical engineering as an interdisciplinary subject.
With 36,000 members (including 1,300 companies) the
VDE Association for Electrical, Electronic & Information
Technologies is one of the largest technical and scientific
associations in Europe. VDE works in the fields of information
technology, energy, medical engineering, microelectronics, micro
and nanotechnology and automation. VDE is headquartered in
Frankfurt am Main, Germany, and has main branches in Brussels,
Belgium and Berlin, Germany.
About Conformis, Inc.
Conformis is a medical technology company that
uses its proprietary iFit Image-to-Implant technology platform to
develop, manufacture, and sell joint replacement implants and
instruments that are individually sized and shaped, which we refer
to as personalized, individualized, or sometimes as customized, to
fit each patient’s unique anatomy. Conformis offers a broad
line of sterile, personalized knee and hip implants and single-use
instruments delivered to hospitals. In clinical
studies, the Conformis iTotal CR knee replacement system
demonstrated superior clinical outcomes, including better function
and greater patient satisfaction, compared to traditional,
off-the-shelf implants. Conformis owns or exclusively
in-licenses issued patents and pending patent applications that
cover personalized implants and patient-specific instrumentation
for all major joints.
For more information,
visit www.conformis.com. To receive future releases in
e-mail alerts, sign up at ir.conformis.com.
CONTACT:
Investor Contact
ir@conformis.com
+1 (781) 374-5598
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