Several organizations are evacuating workers from the three countries where a five-month old Ebola outbreak has worsened.

The Peace Corps said Wednesday that it was temporarily removing 340 volunteers working in Liberia, Sierra Leone and Guinea because of virus's spread. Two corps volunteers were placed in isolation and under observation--though aren't symptomatic--after coming in contact with an individual who later died of Ebola, a spokeswoman said.

Two U.S. faith-based organizations that are helping to treat Ebola patients in Liberia and have had American staff infected said they were evacuating nonessential personnel due to spread of the virus, as well as security issues. Another U.S. citizen and a top doctor from Sierra Leone have died.

The developments highlight the risks for foreigners as well as for health staff treating Ebola patients. And they underscore the gravity of the evolving crisis in a poor corner of West Africa where government authorities and international health workers have struggled to bring the deadly outbreak under control.

"This is a growing crisis of proportions that will cost, we think, thousands of lives and maybe more," said Bruce Johnson, president of SIM USA, a Charlotte, N.C., missionary group, one of the groups helping Ebola patients in Liberia. "The international community has the resources and people to respond, but they need to respond."

While organizations are pulling out nonessential personnel, he said more funds and health-care workers are needed on the ground to fight the resurgence of the disease in the three African countries.

SIM will evacuate about 60 to 70 spouses, children and other nonmedical staff in the next few days, Mr. Johnson said, but staff needed to run the centers will stay. The treatment center has stopped admitting new patients temporarily. "This is due primarily to the escalation of the disease--it's spreading further and faster," Mr. Johnson said. "It's really a safety precaution."

SIM's partner, Samaritan's Purse, a Christian relief organization based in Boone, N.C., also said was curtailing operations in Liberia "because of instability and ongoing security issues in the area."

Some health-care workers combatting the outbreak have met with resistance from locals who have refused to let them treat loved ones or remove their still infectious dead bodies.

Meanwhile, international airline and health authorities are considering changes to passenger-screening rules and procedures, as well as possible steps to facilitate air-ambulance services for Ebola victims, according to the International Civil Aviation Organization, the aviation arm of the United Nations.

Airlines for America, the U.S. trade group, said Wednesday that its members remain in contact with the CDC "on actions the U.S. government is taking regarding potential health concerns." Airlines for America, the U.S. trade group, said Wednesday that its members remain in contact with the CDC "on actions the U.S. government is taking regarding potential health concerns." United Continental Airlines Inc. and Delta Air LinesUnited Continental Airlines Inc. and Delta Air Lines Inc. are continuing their flights to and from West Africa.

The U.S. Centers for Disease Control and Prevention has warned doctors to be on the alert for patients from West Africa with Ebola symptoms and says it is sending more disease detectives to the region. The two infected doctors, Kent Brantly, a doctor from Fort Worth, Texas, doing a post-residency on medical missionary program with Samaritan's Purse, and Nancy Writebol, who went to Liberia last year with her husband and is personnel director for a SIM team, are in stable condition but have up and down days, Mr. Johnson said.

The U.K. government held an ad hoc emergency committee meeting on Wednesday to discuss possible measures to help control the outbreak as well as respond to possible Ebola cases in U.K. nationals in West Africa.

Ebola experts say the first several days of illness are critical, with most deaths from the disease occurring between the eighth and 10th day of illness. Roughly two-thirds of the Ebola patients in the current outbreak in three West African countries have died. The incubation period for Ebola lasts between two and 21 days.

While the disease isn't airborne, it is easily transmissible through bodily fluids exchanged even through skin contact. Transferring the ill to higher-tech hospitals isn't easy.

The University Medical Center Hamburg-Eppendorf in Germany, which has a treatment center equipped to handle Ebola patients, said it had received an informal request to take a patient from West Africa, but the request was withdrawn.

"We don't expect any patients to be moved [here]," Christine Trowitzsch, a spokeswoman, said in an emailed statement. She didn't provide further details.

The two infected doctors, Kent Brantly, a doctor from Fort Worth, Texas, doing a post-residency on medical missionary program with Samaritan's Purse, and Nancy WritebolMs. Writebol is isolated and quarantined in her own home; doctors go in and out in protective equipment to treat her, Mr. Johnson said. Ms. Writebol's husband also has donned protective equipment so he could enter the house and spend time "talking to her eye to eye," Mr. Johnson said.

Dr. Brantly is isolated in another home. Both were moved from a hospital so they could be more comfortable, Mr. Johnson said, adding that the organizations are following safety protocols laid out by the CDC and World Health Organization.

It isn't known how the two were infected. Dr. Brantly was treating Ebola patients. Ms. Writebol was spraying down medical personnel at the Ebola treatment center as part of a decontamination process. Mr. Johnson said SIM asked a local CDC team to recheck its safety procedures at its Ebola treatment center.

Andrea Thomas, Nicholas Winning, Doug Cameron and Andy Pasztor contributed to this article.

Write to Betsy McKay at Betsy.McKay@wsj.com

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