UNITED STATES
SECURITIES AND EXCHANGE COMMISSION
Washington D.C. 20549
FORM 11-K
(Mark One)
 ýANNUAL REPORT PURSUANT TO SECTION 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934
For the fiscal year ended December 31, 2021
OR
 
 ¨TRANSITION REPORT PURSUANT TO SECTION 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934
Commission file number 001-37702
AMGEN RETIREMENT AND SAVINGS PLAN
(Full title of the plan)
AMGEN INC.
(Name of issuer of the securities held)
 
One Amgen Center Drive, 91320-1799
Thousand Oaks, California (Zip Code)
(Address of principal executive offices) 






Amgen Retirement and Savings Plan
Audited Financial Statements
and Supplemental Schedules
Year Ended December 31, 2021

Contents
 




Report of Independent Registered Public Accounting Firm

To the Plan Participants and the Plan Administrator of Amgen Retirement and Savings Plan
Opinion on the Financial Statements
We have audited the accompanying statements of net assets available for benefits of Amgen Retirement and Savings Plan (the Plan) as of December 31, 2021 and 2020, and the related statement of changes in net assets available for benefits for the year ended December 31, 2021, and the related notes (collectively referred to as the “financial statements”). In our opinion, the financial statements present fairly, in all material respects, the net assets available for benefits of the Plan at December 31, 2021 and 2020, and the changes in its net assets available for benefits for the year ended December 31, 2021, in conformity with U.S. generally accepted accounting principles.
Basis for Opinion
These financial statements are the responsibility of the Plan’s management. Our responsibility is to express an opinion on the Plan’s financial statements based on our audits. We are a public accounting firm registered with the Public Company Accounting Oversight Board (United States) (PCAOB) and are required to be independent with respect to the Plan in accordance with the U.S. federal securities laws and the applicable rules and regulations of the Securities and Exchange Commission and the PCAOB.
We conducted our audits in accordance with the standards of the PCAOB. Those standards require that we plan and perform the audit to obtain reasonable assurance about whether the financial statements are free of material misstatement, whether due to error or fraud. The Plan is not required to have, nor were we engaged to perform, an audit of its internal control over financial reporting. As part of our audits we are required to obtain an understanding of internal control over financial reporting but not for the purpose of expressing an opinion on the effectiveness of the Plan’s internal control over financial reporting. Accordingly, we express no such opinion.
Our audits included performing procedures to assess the risks of material misstatement of the financial statements, whether due to error or fraud, and performing procedures that respond to those risks. Such procedures included examining, on a test basis, evidence regarding the amounts and disclosures in the financial statements. Our audits also included evaluating the accounting principles used and significant estimates made by management, as well as evaluating the overall presentation of the financial statements. We believe that our audits provide a reasonable basis for our opinion.
Supplemental Schedules Required by ERISA
The accompanying supplemental schedules of assets (held at end of year) and loans or fixed income obligations in default or classified as uncollectible as of December 31, 2021, and assets (acquired and disposed of within year) and delinquent participant contributions for the year then ended, (referred to as the “supplemental schedules”), have been subjected to audit procedures performed in conjunction with the audit of the Plan’s financial statements. The information in the supplemental schedules is the responsibility of the Plan’s management. Our audit procedures included determining whether the information reconciles to the financial statements or the underlying accounting and other records, as applicable, and performing procedures to test the completeness and accuracy of the information presented in the supplemental schedules. In forming our opinion on the information, we evaluated whether such information, including its form and content, is presented in conformity with the Department of Labor’s Rules and Regulations for Reporting and Disclosure under the Employee Retirement Income Security Act of 1974. In our opinion, the information is fairly stated, in all material respects, in relation to the financial statements as a whole.
/s/ ERNST & YOUNG LLP

We have served as the Plan’s auditor since at least 1989, but we are unable to determine the specific year.
Los Angeles, California
June 23, 2022

1



Amgen Retirement and Savings Plan
Statements of Net Assets Available for Benefits

 December 31,
 20212020
Assets
Investments at fair value$6,436,111,194 $6,028,344,525 
Investments in fully benefit-responsive investment contracts at contract value714,985,494 678,722,325 
Notes receivable from participants30,628,567 33,228,057 
Other – principally due from broker4,502,530 9,187,314 
Total assets7,186,227,785 6,749,482,221 
Liabilities
Other – principally due to broker6,957,185 8,741,768 
Total liabilities6,957,185 8,741,768 
Net assets available for benefits$7,179,270,600 $6,740,740,453 
See accompanying notes.

2



Amgen Retirement and Savings Plan
Statement of Changes in Net Assets Available for Benefits

 Year Ended December 31,
 2021
Additions to (deductions from) net assets:
Employer contributions$192,549,554 
Participant contributions170,659,097 
Rollover contributions37,446,206 
Interest and dividend income44,783,341 
Net realized/unrealized gains637,968,589 
Interest income on notes receivable from participants1,527,815 
Benefits paid(633,334,430)
Investment and administrative fees(13,070,025)
Net increase438,530,147 
Net assets available for benefits at beginning of year6,740,740,453 
Net assets available for benefits at end of year$7,179,270,600 
See accompanying notes.
3



Amgen Retirement and Savings Plan
Notes to Financial Statements
December 31, 2021
1. Description of the Plan
The following description of the Amgen Retirement and Savings Plan (the Plan) provides only general information. Participants should refer to the Plan document for a more complete description of the Plan’s provisions.
General
The Plan was established effective April 1, 1985, and was amended and restated effective January 1, 2017, and subsequently amended, with the most recent amendment adopted on October 25, 2021. The Plan is a defined contribution plan covering substantially all domestic employees of Amgen Inc. (the Company or Amgen) and participating subsidiaries. The Plan is intended to qualify under sections 401(a) and 401(k) of the Internal Revenue Code of 1986 (the Code) (see Note 4, Income Tax Status) and section 407(d)(3)(A) of the Employee Retirement Income Security Act of 1974 (ERISA).
Contributions
Subject to certain limitations (as defined in the Plan), participants may elect to contribute up to 30% of their eligible compensation in pre-tax contributions, Roth contributions (in accordance with the Code), after-tax contributions or a combination of these types of contributions (together, Individual Contributions). A participant’s combined pre-tax contributions and Roth contributions (exclusive of catch-up contributions discussed below) are subject to Internal Revenue Service (IRS) and Plan limits and could not exceed a maximum of $19,500 in 2021. Participant after-tax contributions are subject to IRS and Plan limitations and could not exceed a maximum of $9,500 in 2021. Unless an employee has voluntarily enrolled in the Plan or has declined to participate in the Plan within the first 30 days of employment, all newly eligible participants are automatically enrolled in the Plan, and contributions equal to 5% of their eligible compensation are withheld and contributed to the Plan as pre-tax contributions; such contributions are automatically increased by 1% per year until their contributions reach 10% of their eligible compensation. Participants may elect to adjust, cease or resume their Individual Contributions at any time.
Participants who are at least age 50 by the close of the Plan year may also elect to make certain additional Individual Contributions, referred to as catch-up contributions, that are subject to IRS and Plan limitations and could not exceed $6,500 in 2021. Catch-up contributions may be made as pre-tax contributions, Roth contributions or a combination of these types of contributions. Participants may also contribute pre-tax, Roth and after-tax amounts representing distributions from certain other retirement plans qualified in the United States or certain individual retirement accounts (IRAs), referred to as rollover contributions (as defined in the Plan). In addition, eligible participants that received coronavirus-related distributions from the Plan, as discussed below, or any other plan, may make contributions to the Plan during a specified period in an aggregate amount not to exceed such coronavirus-related distributions; these contributions will be treated in the same manner as rollover contributions.
Each pay period, the Company makes a non-elective contribution for all eligible participants, whether or not they have elected to make Individual Contributions to the Plan, equal to 5% of each participant’s eligible compensation (Core Contributions) up to a maximum of $14,500 in 2021. In addition, the Company makes a contribution equal to amounts contributed by the participant as pre-tax contributions or Roth contributions, including such contributions designated as catch-up contributions, of up to 5% of eligible compensation (Matching Contributions) up to a maximum of $14,500 in 2021.
Also, the Company can, at its discretion, make a special contribution (Special Contribution) on behalf of a participant who is in his or her initial year of employment with the Company and who could not make the maximum participant contribution permitted under the Plan because in the same Plan year he or she previously made pre-tax salary deferrals under a prior unrelated employer’s qualified plan.
Participants select the investments in which their Individual Contributions, including their Core Contributions, Matching Contributions and Special Contributions, if any, (collectively, Company Contributions) are to be invested, electing among various alternatives, including Amgen common stock (Amgen stock). Participants may direct a maximum of 20% of contributions to be invested in Amgen stock. In addition, participants may transfer amounts among the investment options at any time, subject to certain limitations. Notwithstanding the foregoing, if 20% or more of the value of a participant’s Plan account is invested in Amgen stock, the Plan document provides that no transfers from other investment options can be made to invest in Amgen stock.
4



Amgen Retirement and Savings Plan
Notes to Financial Statements (continued)
The accounts of participants who had never made an investment election are allocated to investments under a qualified default investment alternative, which is intended to be compliant with ERISA regulations. At any time, participants may elect to alter the investments in their accounts made under a qualified default investment alternative.
Vesting
Participants are immediately vested with respect to their Individual Contributions, Matching Contributions and Special Contributions, if any, and earnings and losses (hereafter referred to as earnings) thereon. Participants hired prior to January 1, 2020, are also immediately vested with respect to their Core Contributions and earnings thereon. Participants hired on or after January 1, 2020, vest in full with respect to their Core Contributions and earnings thereon after three years of service, as defined by the terms of the Plan, or upon reaching age 65 while employed by Amgen, if earlier. If a participant ceases to be an employee before fully vesting in their account, the non-vested portion of the participant’s account will be treated as a forfeiture, as defined by the terms of the Plan, on the earlier of (a) the date the participant incurs a five-year break in service, as defined by the terms of the Plan or, (b) the date the participant receives a distribution of the entire vested portion of their account.
Participant Accounts
Each participant’s account is credited with: (a) the participant’s Individual Contributions; (b) an allocation of Company Contributions; and (c) earnings. The benefit to which a participant is entitled is the benefit that can be provided from the participant’s account.
Plan Investments
Plan participants can invest in seven different asset classes as well as Amgen stock or can actively manage their account under a self-directed brokerage arrangement in which a wider array of investment options are available. The value of an investment in an asset class is determined by its underlying investment vehicles, which may include one or more of the following: mutual funds, collective trust funds and portfolios which are separately managed exclusively for the benefit of Plan participants and their beneficiaries (separately managed portfolios). The separately managed portfolios invest in various types of assets, including publicly traded common and preferred stocks, collective trust funds and investment contracts. The asset classes are designed to provide participants with choices among a variety of investment objectives.
Payments of Benefits
Subject to Plan limitations, upon termination of employment, including termination due to disability (as defined in the Plan) or retirement, participants may elect to receive a full or partial distribution of their account balance in: (a) a single payment in cash; (b) a single distribution in full shares of Amgen stock (with any fractional shares paid in cash); (c) a single distribution paid in a combination of cash and full shares of Amgen stock; (d) cash installments over 10 years; or (e) a rollover distribution to an eligible retirement plan.
Participants may also elect to maintain their account balance in the Plan subsequent to termination of employment, provided that their account balance is greater than $1,000.
If a participant dies before receiving the value of his or her account balance, the participant’s beneficiary may elect to receive the distribution of remaining funds from among the alternatives described above, subject to certain Plan limitations.
Certain restrictions apply to withdrawals from the Plan while a participant continues to be employed by the Company, including coronavirus-related withdrawals, which were permitted under the Coronavirus Aid, Relief and Economic Security Act (CARES Act) enacted on March 27, 2020. In response to the CARES Act, the Plan voluntarily made a number of modifications related to withdrawals. The Plan adopted only those provisions of the CARES Act that (a) permitted participants who turned 70½ or older in 2019 to waive the requirement to take a minimum distribution in 2020 and (b) allowed qualified participants to take tax-favored distributions of up to $100,000, repayable if desired by the participant in three years, for qualifying coronavirus-related reasons through December 30, 2020.
Amgen Stock Dividends
Participants that invest in Amgen stock may elect to receive distributions of cash with respect to dividends the Company pays on Amgen stock or reinvest such dividends to acquire additional shares of Amgen stock.
5



Amgen Retirement and Savings Plan
Notes to Financial Statements (continued)
Notes Receivable from Participants
Subject to certain restrictions, a participant can have up to two loans outstanding at any one time from his or her Plan account with a combined maximum loan amount that may not exceed the lesser of: (a) 50% of the participant’s account balance (exclusive of amounts related to Roth contributions and earnings thereon) or (b) $50,000 less certain adjustments, as applicable (as defined in the Plan). A participant’s loan is secured by his or her Plan account balance. Loans bear interest at fixed rates which, until changed by the Company, are based on the prime rate plus one percentage point as published in The Wall Street Journal, determined as of the last day of the calendar quarter preceding origination or such other rate as may be required by law. Loans are generally payable in installments over periods of up to five years, unless the loan is used to acquire a principal residence for which the term of the loan may be up to 20 years. Principal and interest payments are allocated to the participant’s account.
Plan Termination
Although it has not expressed any intent to do so, the Company has the right under the Plan to terminate the Plan subject to the provisions of ERISA. Upon termination, participants would receive distributions of their account balances.
Trustees and Custodians
Bank of America, N.A. is the Plan’s trustee and custodian with respect to the self-directed brokerage arrangement and the Amgen common stock fund. The Northern Trust Company, NA (Northern) is the Plan’s trustee and custodian with respect to the asset classes.
2. Summary of Significant Accounting Policies
Basis of Accounting
The accompanying financial statements are prepared on the accrual basis of accounting. Benefits to participants are recorded when paid.
Fair Value Measurement
The investments of the Plan are reported at fair value, except for fully benefit-responsive investment contracts, discussed below. Fair value is generally defined as the price that would be received to sell an asset or paid to transfer a liability (the exit price) in an orderly transaction between market participants at the measurement date (see Note 3, Fair Value Measurements).
Investment Income and Losses
Dividend income is recognized on the ex-dividend date, and interest income is recorded on an accrual basis. Unrealized gains and losses on investments are measured by the change in the difference between the fair value and cost of the securities held at the beginning of the year (or date purchased if acquired during the Plan year) and the end of the year. Realized gains and losses from security transactions are recorded based on the weighted-average cost of securities sold.
Fully Benefit-Responsive Investment Contracts
As of December 31, 2021 and 2020, the Plan had fully benefit-responsive investment contracts, including synthetic investment contracts and an insurance separate accounts contract (collectively, security-backed contracts). The synthetic investment contracts are comprised of wrapper contracts issued by insurance companies backed by the Plan’s ownership in collective trust funds that invest in fixed income securities. The insurance separate accounts contract is a contract issued by an insurance company backed by specified separate accounts of the issuer which are comprised of fixed income securities. Contract value is the relevant measurement attribute for security-backed contracts because this is the amount participants would receive if they were to initiate qualified transactions related to these investments. The issuers of the Plan’s security-backed contracts credit the Plan with stated rates of interest, and the issuers guarantee that all qualified participant withdrawals related to the contracts will be at contract value, except as discussed below. The crediting rates provide for realized and unrealized gains and losses on the underlying assets to be amortized over the expected duration of the underlying investments through adjustments to the future interest crediting rates rather than being reflected immediately in the net assets of the Plan. The contract values of the Plan’s security-backed contracts were as follows:
6



Amgen Retirement and Savings Plan
Notes to Financial Statements (continued)
December 31,
20212020
Synthetic investment contracts$533,077,342 $501,806,073 
Insurance separate accounts contract181,908,152 176,916,252 
Total fully benefit-responsive investment contracts$714,985,494 $678,722,325 
The security-backed contracts provide for withdrawals at other than contract value associated with certain events which are not in the ordinary course of Plan operations. These withdrawals are made at contract value, modified by a market value adjustment as defined in the contract. Circumstances which may trigger a market value adjustment are generally defined as any event that, in the reasonable determination of the issuer, has or will have a material adverse effect on the issuer’s interest under the contract. Such events may include, but are not limited to: (a) material amendments to the Plan’s structure or administration; (b) changes in or the creation of competing investment options; (c) complete or partial termination of the Plan; (d) removal of a specifically identifiable group of employees from coverage under the Plan; (e) a change in law, regulation, ruling, administrative position, or accounting standard applicable to the Plan; or (f) communication to Plan participants designed to influence a participant not to invest in the asset class that contains these contracts. The Company does not believe that the occurrence of any such event, which would limit the Plan’s ability to transact at contract value with participants, is probable.
These security-backed contracts are evergreen contracts with no maturity dates, but do contain termination provisions. The issuer is obligated to pay the excess contract value when the fair value of the underlying investments equals zero. In addition, if the Plan defaults in its obligations under the security-backed contract and such default is not corrected within the time permitted by the contract, then the contract may be terminated by the issuer and the Plan will receive the fair value of the underlying investments as of the date of termination.
Notes Receivable from Participants
Notes receivable from participants are carried at their unpaid balance plus accrued but unpaid interest, as applicable.
Due from/to Brokers
Purchases and sales of investments are recorded on a trade-date basis. Amounts due from and due to brokers arise from unsettled sale and purchase transactions, respectively.
Use of Estimates
The preparation of financial statements in conformity with U.S. generally accepted accounting principles (GAAP) requires management to make estimates and assumptions that affect the amounts reported in the financial statements and accompanying notes. Actual results could differ from those estimates.
Risks and Uncertainties
The Plan provides for investment options representing varied combinations of equities (including Amgen stock), fixed income, and other investments. Investments, in general, particularly in securities, are exposed to various risks, such as interest rate, inflation, market and credit risks, among others. Market risk includes global events which could impact the value of investments, including securities, such as a pandemic or international conflict. Due to the level of risk associated with certain investments, including securities, it is at least reasonably possible that changes in the values of the Plan’s investments, including securities, will occur in the near term and that such changes could materially affect participant account balances and the amounts reported in the Plan’s financial statements.

7



Amgen Retirement and Savings Plan
Notes to Financial Statements (continued)
3. Fair Value Measurements
The Plan uses various valuation approaches in determining the fair value of investments within a hierarchy that maximizes the use of observable inputs and minimizes the use of unobservable inputs by requiring that observable inputs be used when available. Observable inputs are inputs that market participants would use in pricing the investment based on market data obtained from independent sources. Unobservable inputs are inputs that reflect assumptions about the inputs that market participants would use in pricing the investment and are developed based on the best information available in the circumstances. The fair value hierarchy is divided into three levels based on the source of inputs as follows:
Level 1 – Valuations based on unadjusted quoted prices in active markets for identical investments that the Plan has the ability to access;
Level 2 – Valuations for which all significant inputs are observable, either directly or indirectly, other than Level 1 inputs;
Level 3 – Valuations based on inputs that are unobservable and significant to the overall fair value measurement.
The availability of observable inputs can vary among the various types of investments. To the extent that the valuation is based on models or inputs that are less observable or unobservable in the market, the determination of fair value requires more judgment. In certain cases, the inputs used for measuring fair value may fall into different levels of the fair value hierarchy. In such cases, for financial statement disclosure purposes, the level in the fair value hierarchy within which the fair value measurement is categorized is based on the lowest level of input used that is significant to the overall fair value measurement.
The following fair value hierarchy tables present information about each major class/category of the Plan’s investments measured at fair value:
 
Fair value measurements at December 31, 2021, using
 Quoted prices in active markets for identical assets
(Level 1)
Significant
other observable
inputs
(Level 2)
Significant
unobservable
inputs
(Level 3)
Total
Amgen stock$331,811,884 $— $— $331,811,884 
Cash and cash equivalents49,649,048 — — 49,649,048 
Collective trust funds— 3,643,993,561 — 3,643,993,561 
Common and preferred stocks1,546,823,788 — — 1,546,823,788 
Debt securities— 4,828 — 4,828 
Mutual funds81,887,302 — — 81,887,302 
Self-directed brokerage accounts780,896,567 1,044,216 — 781,940,783 
Total investments at fair value$2,791,068,589 $3,645,042,605 $— $6,436,111,194 
 
8



Amgen Retirement and Savings Plan
Notes to Financial Statements (continued)
 
Fair value measurements at December 31, 2020, using
 Quoted prices in active markets for identical assets
(Level 1)
Significant
other observable
inputs
(Level 2)
Significant
unobservable
inputs
(Level 3)
Total
Amgen stock$352,404,662 $— $— $352,404,662 
Cash and cash equivalents32,090,680 — — 32,090,680 
Collective trust funds— 3,654,353,052 — 3,654,353,052 
Common and preferred stocks1,259,896,607 — — 1,259,896,607 
Debt securities59 4,969 — 5,028 
Mutual funds92,035,145 — — 92,035,145 
Self-directed brokerage accounts636,454,755 1,104,596 — 637,559,351 
Total investments at fair value$2,372,881,908 $3,655,462,617 $— $6,028,344,525 
The fair values of substantially all common stocks (including Amgen stock), preferred stocks, publicly traded mutual funds and underlying investments of self-directed brokerage accounts are valued using quoted market prices in active markets with no valuation adjustment.
Collective trust funds represent interests in pooled investment vehicles designed typically for collective investment of employee benefit trusts. The fair values of these investments are determined by reference to the net asset value per unit provided by the fund managers as the basis for current transactions.
Debt securities are valued by taking into consideration valuations obtained from third-party pricing services. The pricing services use industry-standard valuation models, including both income- and market-based approaches, for which all significant inputs are observable either directly or indirectly to estimate fair value. The inputs include reported trades of and broker-dealer quotes on the same or similar securities; issuer credit spreads; benchmark securities; and other observable inputs.
4. Income Tax Status
The Plan received a determination letter from the IRS dated February 22, 2018, stating that, conditioned on the adoption of proposed Plan amendments submitted to the IRS on February 15, 2018, the Plan is qualified, in form, under Section 401(a) of the Code and, therefore, the related trust is exempt from taxation. There have been five subsequent amendments to the Plan, including amendments to satisfy the conditions in the determination letter. Once qualified, the Plan is required to operate in conformity with the Code to maintain its qualification. The Company believes the Plan is currently being operated in compliance with the applicable requirements of the Code and, therefore, believes that the Plan is qualified and the related trust is tax exempt. The Company has indicated that it currently intends to continue to take the necessary steps, if any, to maintain the Plan’s compliance with the applicable requirements of the Code.
5. Party-in-Interest Transactions
Parties-in-interest are certain entities defined under Department of Labor regulations, including Amgen, and other parties that provide services to the Plan, such as the trustees, custodians and investment managers. The Plan pays the trustees certain administrative and investment management fees, and the Company pays certain administrative fees on behalf of the Plan. The Plan invests in collective trust funds managed by Northern, certain of the Plan’s investment managers and other third parties and may invest in securities of entities that are parties-in-interest. The Plan also invests in shares of common stock of Amgen and receives dividends on those shares. Notes receivable from participants are also considered party-in-interest transactions. In addition, Northern enters into security-backed contracts with certain insurance companies on behalf of the Plan.

9



Amgen Retirement and Savings Plan
Notes to Financial Statements (continued)
6. Reconciliation of Financial Statements to the Form 5500
The reconciliation of net assets available for benefits per the financial statements to the Form 5500 consisted of the following:
 December 31,
 20212020
Net assets available for benefits per the financial statements$7,179,270,600 $6,740,740,453 
Adjustment to fair value for fully benefit-responsive investment contracts
2,393,677 17,810,584 
Amounts allocated to withdrawing participants(3,044,375)(2,432,934)
Deemed loans(384,631)(337,488)
Net assets per the Form 5500$7,178,235,271 $6,755,780,615 
The following is a reconciliation of the net investment gain per the financial statements to the Form 5500: 
 Year Ended
December 31,
2021
Interest and dividend income$44,783,341 
Net realized/unrealized gains637,968,589 
Net investment income per the financial statements682,751,930 
Adjustment from fair value to contract value for fully benefit-responsive investment contracts:
Less prior-year adjustment(17,810,584)
Add current-year adjustment2,393,677 
Total net investment gain per the Form 5500$667,335,023 
The following is a reconciliation of expenses per the financial statements to the Form 5500:
 Year Ended
December 31,
2021
Benefits paid$(633,334,430)
Investment and administrative fees(13,070,025)
Total expenses per the financial statements(646,404,455)
Amounts allocated to withdrawing participants at December 31, 2020
2,432,934 
Amounts allocated to withdrawing participants at December 31, 2021
(3,044,375)
Deemed loans at December 31, 2020
337,488 
Deemed loans at December 31, 2021
(384,631)
Total expenses per the Form 5500$(647,063,039)
10


Supplemental Schedule
Amgen Retirement and Savings Plan
EIN: 95-3540776 Plan: #001
As of December 31, 2021
Schedule H, line 4i – Schedule of Assets (Held at End of Year)
Identity of IssueDescription of InvestmentCurrent Value
Amgen stock*Employer Securities 1,474,916 shares$331,811,884 
$331,811,884 
Capital Preservation Asset Class:
Wells Fargo Fixed Income Fund L*Collective Trust Fund 21,790,625 units317,243,168 
Wells Fargo Fixed Income Fund F*Collective Trust Fund 14,014,530 units217,778,788 
Metropolitan Life Contract*Insurance Separate Accounts Investment Contract 1,460,908 units182,357,216 
NT Collective Short Term Investment Fund*Collective Trust Fund 51,299,735 units51,299,735 
Wells Fargo BlackRock Short Term Investment Fund S*Collective Trust Fund 37,867,822 units37,870,238 
Wrapper Contracts— 
Total Capital Preservation Asset Class806,549,145 
Fixed Income Asset Class:
MetLife Core Plus Collective Fund*Collective Trust Fund 16,606,811 units179,851,763 
Wellington Core Bond Plus Portfolio Collective Investment Trust II*Collective Trust Fund 13,448,169 units179,129,606 
Schroder Global Strategic Bond Trust Class W*Collective Trust Fund 4,557,016 units46,390,419 
Putnam Absolute Return Fixed Income Fund*Collective Trust Fund 604,008 units44,835,509 
NT Collective Aggregate Bond Index Fund / Non Lending*Collective Trust Fund 114,177 units18,437,263 
Banc America Alternative Loan Trust Series 2004-6 Class 4A 15.0% Due 10-25-2048*Corporate Bond 2,439 units2,605 
Interest Bearing CashCash and Cash Equivalents 2,022 units2,022 
GMAC Mortgage Loan Trust 2003/J10 4.75% Due 01/25/2019Corporate Bond 1,396 units1,370 
Kaupthing Bank HF 02/28/2020 In DefaultCorporate Bond 310,000 units775 
Total Fixed Income Asset Class468,651,332 
Fixed Income Index Asset Class:
NT Collective Aggregate Bond Index Fund / Non Lending*Collective Trust Fund 6,207,694 units1,002,418,500 
Total Fixed Income Index Asset Class1,002,418,500 
U.S. Equity Asset Class:
NT Collective Russell 3000 Index Fund / Non Lending*Collective Trust Fund 1,445,032 units106,413,582 
Amazon Inc.Common and Preferred Stock 14,229 shares47,444,324 
Interest Bearing CashCash and Cash Equivalents 46,095,892 units46,095,892 
Visa Inc. Class ACommon and Preferred Stock 192,841 shares41,790,573 
Facebook, Inc.Common and Preferred Stock 100,657 shares33,855,982 
Microsoft CorporationCommon and Preferred Stock 72,522 shares24,390,599 
11



Schedule H, line 4i – Schedule of Assets (Held at End of Year) (continued)
Identity of IssueDescription of InvestmentCurrent Value
Netflix, Inc.Common and Preferred Stock 40,368 shares24,319,298 
IntuitCommon and Preferred Stock 29,977 shares19,281,806 
Mastercard Inc. Class ACommon and Preferred Stock 52,567 shares18,888,374 
TransDigm Group Inc.Common and Preferred Stock 28,227 shares17,960,276 
CoStar Group Inc.Common and Preferred Stock 222,683 shares17,598,637 
Applovin Corporation Class ACommon and Preferred Stock 185,944 shares17,527,081 
Sea LimitedCommon and Preferred Stock 70,697 shares15,815,626 
Match Group Inc.Common and Preferred Stock 117,282 shares15,510,545 
Heico Corporation Class ACommon and Preferred Stock 117,615 shares15,115,880 
ServiceNow, Inc.Common and Preferred Stock 23,115 shares15,004,178 
Applied Materials Inc.Common and Preferred Stock 95,000 shares14,949,200 
Wayfair Inc. Class ACommon and Preferred Stock 71,787 shares13,637,376 
NT Collective Short Term Investment Fund*Collective Trust Fund 13,626,293 units13,626,293 
UnitedHealth Group Inc.Common and Preferred Stock 27,040 shares13,577,866 
Lam Research CorporationCommon and Preferred Stock 18,761 shares13,491,973 
Qorvo, Inc.Common and Preferred Stock 81,870 shares12,803,649 
KKR & Company Inc. Class ACommon and Preferred Stock 169,936 shares12,660,232 
Skyworks Solutions IncCommon and Preferred Stock 80,902 shares12,551,136 
Salesforce.com Inc.Common and Preferred Stock 49,096 shares12,476,766 
The Carlyle Group Inc.Common and Preferred Stock 223,234 shares12,255,547 
Alphabet Inc.Common and Preferred Stock 4,132 shares11,956,314 
STERIS plcCommon and Preferred Stock 49,063 shares11,942,425 
American International Group Inc.Common and Preferred Stock 209,643 shares11,920,301 
Upstart Holdings Inc.Common and Preferred Stock 78,150 shares11,824,095 
Square Inc Class ACommon and Preferred Stock 71,988 shares11,626,782 
Wells Fargo & Company*Common and Preferred Stock 239,853 shares11,508,147 
Ball CorporationCommon and Preferred Stock 116,875 shares11,251,556 
General ElectricCommon and Preferred Stock 117,048 shares11,057,525 
Workday Inc. Class ACommon and Preferred Stock 39,417 shares10,767,936 
Skechers USA Inc. Class ACommon and Preferred Stock 245,480 shares10,653,832 
Danaher CorporationCommon and Preferred Stock 32,341 shares10,640,512 
Entegris Inc.Common and Preferred Stock 75,676 shares10,487,180 
NRG Energy Inc.Common and Preferred Stock 241,511 shares10,404,294 
Lear CorporationCommon and Preferred Stock 55,702 shares10,190,681 
Splunk Inc. Common and Preferred Stock 87,659 shares10,143,899 
Charles River Laboratories International Inc.Common and Preferred Stock 26,467 shares9,972,236 
Clean Harbors Inc.Common and Preferred Stock 98,224 shares9,799,808 
Alphabet Inc. Class CCommon and Preferred Stock 3,386 shares9,797,696 
Catalent Inc.Common and Preferred Stock 76,157 shares9,750,381 
Yum! Brands Inc.Common and Preferred Stock 69,352 shares9,630,219 
12



Schedule H, line 4i – Schedule of Assets (Held at End of Year) (continued)
Identity of IssueDescription of InvestmentCurrent Value
salesforce.com, inc.Common and Preferred Stock 37,746 shares9,592,391 
Cognizant Technology Solutions Corporation Class ACommon and Preferred Stock 105,133 shares9,327,400 
Thermo Fisher CorporationCommon and Preferred Stock 13,781 shares9,195,234 
Paypal Holdings Inc.Common and Preferred Stock 48,661 shares9,176,491 
Wabtec CorporationCommon and Preferred Stock 97,404 shares8,971,882 
Twilio Inc. Class ACommon and Preferred Stock 34,006 shares8,955,140 
Edison InternationalCommon and Preferred Stock 131,133 shares8,949,827 
Uber Technologies Inc.Common and Preferred Stock 208,325 shares8,735,067 
Waste Connections Inc.Common and Preferred Stock 63,754 shares8,687,758 
Synopsys Inc.Common and Preferred Stock 23,498 shares8,659,013 
Abbott LabCommon and Preferred Stock 61,488 shares8,653,821 
Equinix Inc.Common and Preferred Stock 10,222 shares8,646,176 
Autodesk Inc.Common and Preferred Stock 30,639 shares8,615,380 
IHS Markit LimitedCommon and Preferred Stock 63,319 shares8,416,361 
Citigroup Inc.Common and Preferred Stock 139,168 shares8,404,356 
Walt Disney CompanyCommon and Preferred Stock 53,452 shares8,279,180 
Atlassian Corporation PLC Class ACommon and Preferred Stock 21,034 shares8,020,054 
Regeneron Pharmaceuticals, Inc.Common and Preferred Stock 12,651 shares7,989,360 
MSCI Inc.Common and Preferred Stock 12,717 shares7,791,579 
Nvidia CorporationCommon and Preferred Stock 26,280 shares7,729,211 
Henry Schein Inc.Common and Preferred Stock 97,351 shares7,547,623 
Ametek Inc.Common and Preferred Stock 51,281 shares7,540,358 
Align Technology, Inc.Common and Preferred Stock 11,329 shares7,445,192 
FleetCor Technologies, Inc.Common and Preferred Stock 33,053 shares7,398,584 
Newell Brands Inc.Common and Preferred Stock 334,971 shares7,315,767 
Shopify IncCommon and Preferred Stock 5,260 shares7,245,071 
Equitable Holdings Inc.Common and Preferred Stock 220,932 shares7,244,360 
Western Alliance BancorporationCommon and Preferred Stock 65,594 shares7,061,194 
Amphenol Corporation Class ACommon and Preferred Stock 80,122 shares7,007,470 
MetLife Inc.*Common and Preferred Stock 111,292 shares6,954,637 
FMC CorporationCommon and Preferred Stock 62,937 shares6,916,147 
Baker Hughes CompanyCommon and Preferred Stock 285,320 shares6,864,799 
American Express CompanyCommon and Preferred Stock 41,593 shares6,804,615 
Halliburton CompanyCommon and Preferred Stock 292,700 shares6,694,049 
Merit Medical Systems Inc.Common and Preferred Stock 107,250 shares6,681,675 
UGI CorporationCommon and Preferred Stock 143,440 shares6,585,330 
Halozyme Therapeutics Inc.Common and Preferred Stock 163,603 shares6,578,477 
PVH CorporationCommon and Preferred Stock 61,570 shares6,566,441 
Zoetis Inc. Class ACommon and Preferred Stock 26,840 shares6,549,765 
Sensata Technologies BV HoldingCommon and Preferred Stock 105,381 shares6,500,954 
Intuitive Surgical, Inc.Common and Preferred Stock 17,853 shares6,414,583 
DEX Inc.Common and Preferred Stock 11,824 shares6,348,897 
13



Schedule H, line 4i – Schedule of Assets (Held at End of Year) (continued)
Identity of IssueDescription of InvestmentCurrent Value
Huntington Bancshares Inc.Common and Preferred Stock 405,224 shares6,248,554 
Gildan Activewear Inc.Common and Preferred Stock 144,706 shares6,134,087 
Dow Inc.Common and Preferred Stock 107,301 shares6,086,113 
Matson Inc.Common and Preferred Stock 67,372 shares6,065,501 
Charter Communications, Inc. Class ACommon and Preferred Stock 8,952 shares5,836,435 
Linde PLCCommon and Preferred Stock 16,825 shares5,828,685 
J2 Global Inc.Common and Preferred Stock 52,238 shares5,791,105 
Amdocs LimitedCommon and Preferred Stock 75,138 shares5,623,328 
LKQ CorporationCommon and Preferred Stock 93,108 shares5,589,273 
Illumina, Inc.Common and Preferred Stock 14,680 shares5,584,859 
Hewlett Packard Enterprise CompanyCommon and Preferred Stock 353,520 shares5,575,010 
On Semiconductor CorporationCommon and Preferred Stock 81,350 shares5,525,292 
Voya Financial Inc.Common and Preferred Stock 82,772 shares5,488,611 
McKesson CorporationCommon and Preferred Stock 21,635 shares5,377,812 
Snowflake Inc. Class ACommon and Preferred Stock 15,875 shares5,377,656 
Mohawk Industries Inc.Common and Preferred Stock 29,477 shares5,370,120 
Trinet Group Inc.Common and Preferred Stock 56,279 shares5,361,138 
Capital One Financial CorporationCommon and Preferred Stock 36,776 shares5,335,830 
Floor & Decor Holdings Inc.Common and Preferred Stock 40,408 shares5,253,444 
RingCentral, Inc. Class ACommon and Preferred Stock 28,035 shares5,252,357 
Edwards Lifesciences CorporationCommon and Preferred Stock 40,146 shares5,200,914 
Axis Capital Holdings LimitedCommon and Preferred Stock 95,172 shares5,184,019 
Fresenius Medical CareCommon and Preferred Stock 156,997 shares5,096,123 
IDEX CorporationCommon and Preferred Stock 21,408 shares5,059,139 
Sally Beauty Holdings Inc.Common and Preferred Stock 272,188 shares5,024,590 
Brown & Brown Inc.Common and Preferred Stock 70,006 shares4,920,022 
Warner Music Group Corporation Class ACommon and Preferred Stock 113,275 shares4,891,215 
DoorDash Inc. Class ACommon and Preferred Stock 32,080 shares4,776,712 
Sarepta Therapeutics Inc.Common and Preferred Stock 52,331 shares4,712,407 
Ritchie Bros. Auctioneers Inc.Common and Preferred Stock 75,480 shares4,620,131 
JP Morgan Chase & Company*Common and Preferred Stock 29,161 shares4,617,644 
Frontdoor Inc.Common and Preferred Stock 122,929 shares4,505,348 
Euronet Worldwide Inc.Common and Preferred Stock 37,558 shares4,475,787 
Keysight Technologies Inc.Common and Preferred Stock 21,490 shares4,437,900 
Ingredion Inc.Common and Preferred Stock 45,780 shares4,424,179 
C.H. Robinson Worldwide Inc.Common and Preferred Stock 40,775 shares4,388,613 
NOV Inc.Common and Preferred Stock 322,722 shares4,372,883 
Exxon Mobil CorporationCommon and Preferred Stock 71,323 shares4,364,254 
BWX Technologies Inc.Common and Preferred Stock 90,780 shares4,346,546 
Goldman Sachs Group Inc.Common and Preferred Stock 11,223 shares4,293,359 
KAR Auction Services Inc.Common and Preferred Stock 265,850 shares4,152,577 
Airbnb Inc. Class ACommon and Preferred Stock 24,567 shares4,090,160 
Hanesbrands Inc.Common and Preferred Stock 243,963 shares4,079,061 
Belden Inc.Common and Preferred Stock 60,843 shares3,999,210 
14



Schedule H, line 4i – Schedule of Assets (Held at End of Year) (continued)
Identity of IssueDescription of InvestmentCurrent Value
National Retail Properties Inc.Common and Preferred Stock 83,009 shares3,990,243 
Generac Holdings Inc.Common and Preferred Stock 11,272 shares3,966,842 
Zendesk Inc.Common and Preferred Stock 37,765 shares3,938,512 
Helen Trustoy LimitedCommon and Preferred Stock 15,815 shares3,866,293 
Middleby CorporationCommon and Preferred Stock 19,340 shares3,805,338 
First American Financial CorporationCommon and Preferred Stock 48,574 shares3,799,944 
Woodward Inc.Common and Preferred Stock 33,902 shares3,710,913 
Cabot CorporationCommon and Preferred Stock 65,262 shares3,667,724 
UBS Group AGCommon and Preferred Stock 204,946 shares3,662,385 
Syneos Health Inc.Common and Preferred Stock 35,181 shares3,612,385 
Textron Inc.Common and Preferred Stock 46,550 shares3,593,660 
Carter Inc.Common and Preferred Stock 34,511 shares3,493,203 
New Relic Inc.Common and Preferred Stock 30,576 shares3,362,137 
Bank of America Corporation*Common and Preferred Stock 75,004 shares3,336,928 
ASGN Inc.Common and Preferred Stock 26,757 shares3,301,814 
MACOM Technology Solutions Holdings Inc.Common and Preferred Stock 41,927 shares3,282,884 
FTI Consulting Inc.Common and Preferred Stock 21,320 shares3,270,914 
Trimble Inc.Common and Preferred Stock 37,506 shares3,270,148 
Pfizer Inc.Common and Preferred Stock 55,126 shares3,255,190 
Tennant CompanyCommon and Preferred Stock 40,004 shares3,241,924 
Rogers CorporationCommon and Preferred Stock 11,834 shares3,230,682 
Copart Inc.Common and Preferred Stock 21,019 shares3,186,901 
GlobalFoundries Inc.Common and Preferred Stock 48,528 shares3,152,864 
ACV Auctions Inc. Class ACommon and Preferred Stock 163,687 shares3,083,863 
Quidel CorporationCommon and Preferred Stock 22,699 shares3,064,138 
Kirby CorporationCommon and Preferred Stock 51,105 shares3,036,659 
Dycom Industries Inc.Common and Preferred Stock 31,731 shares2,975,099 
Royal Dutch Shell PLCCommon and Preferred Stock 67,749 shares2,940,307 
Grand Canyon Education Inc.Common and Preferred Stock 34,288 shares2,938,824 
Prosperity Bancshares Inc.Common and Preferred Stock 40,291 shares2,913,039 
Forward Air CorporationCommon and Preferred Stock 23,791 shares2,880,852 
Graco Inc.Common and Preferred Stock 35,559 shares2,866,767 
8X8 Inc.Common and Preferred Stock 170,204 shares2,852,619 
LPL Financial Holdings Inc.Common and Preferred Stock 17,572 shares2,813,101 
HealthEquity Inc.Common and Preferred Stock 63,397 shares2,804,683 
2U Inc.Common and Preferred Stock 138,322 shares2,776,123 
Carvana Company Class ACommon and Preferred Stock 11,734 shares2,719,824 
Alleghany CorporationCommon and Preferred Stock 3,988 shares2,662,349 
Hologic Inc.Common and Preferred Stock 34,175 shares2,616,438 
Momentive Global Inc.Common and Preferred Stock 123,469 shares2,611,369 
Cloudflare Inc.Common and Preferred Stock 19,762 shares2,598,703 
Cardinal Health, Inc.Common and Preferred Stock 49,914 shares2,570,072 
Gartner Inc.Common and Preferred Stock 7,686 shares2,569,584 
Acadia Healthcare Company Inc.Common and Preferred Stock 42,158 shares2,558,991 
Mid-American Apartment Communities Inc.Common and Preferred Stock 11,112 shares2,549,537 
BankUnited Inc.Common and Preferred Stock 60,154 shares2,545,116 
Bottomline Technologies Inc.Common and Preferred Stock 44,586 shares2,517,771 
SS&C Technologies Holdings Inc.Common and Preferred Stock 30,611 shares2,509,490 
AerCap Holdings N.V.Common and Preferred Stock 38,359 shares2,509,446 
15



Schedule H, line 4i – Schedule of Assets (Held at End of Year) (continued)
Identity of IssueDescription of InvestmentCurrent Value
Cenovus Energy Inc.Common and Preferred Stock 203,926 shares2,504,211 
10X Genomics Inc. Class A Common and Preferred Stock 16,632 shares2,477,503 
AMN Healthcare Services Inc.Common and Preferred Stock 20,132 shares2,462,748 
Booking Holdings Inc.Common and Preferred Stock 956 shares2,293,664 
National Bank Holdings Corporation Class ACommon and Preferred Stock 52,188 shares2,293,141 
Cohen & Steers Inc.Common and Preferred Stock 24,628 shares2,278,336 
Advanced Energy Industries Inc.Common and Preferred Stock 24,932 shares2,270,308 
Tronox Holdings PLCCommon and Preferred Stock 93,356 shares2,243,345 
Mednax Inc.Common and Preferred Stock 82,285 shares2,238,975 
Chemed CorporationCommon and Preferred Stock 4,223 shares2,234,136 
ALLETE Inc.Common and Preferred Stock 33,300 shares2,209,455 
Nasdaq Inc.Common and Preferred Stock 10,520 shares2,209,305 
Itron Inc.Common and Preferred Stock 31,646 shares2,168,384 
Signature BankCommon and Preferred Stock 6,564 shares2,123,257 
Albany International Corporation Class ACommon and Preferred Stock 23,777 shares2,103,076 
Atmos Energy CorporationCommon and Preferred Stock 19,662 shares2,059,988 
ABM Industrials Inc.Common and Preferred Stock 50,404 shares2,059,003 
Sotera Health CompanyCommon and Preferred Stock 86,525 shares2,037,664 
Harsco CorporationCommon and Preferred Stock 119,432 shares1,995,709 
ACI Worldwide Inc.Common and Preferred Stock 57,430 shares1,992,821 
Carlisle Companies Inc.Common and Preferred Stock 7,991 shares1,982,727 
Mimecast LimitedCommon and Preferred Stock 24,684 shares1,964,106 
KBR, Inc.Common and Preferred Stock 41,120 shares1,958,134 
Knowles CorporationCommon and Preferred Stock 83,420 shares1,947,857 
Veracyte Inc.Common and Preferred Stock 47,260 shares1,947,112 
NCR CorporationCommon and Preferred Stock 48,308 shares1,941,982 
Bio-Techne CorporationCommon and Preferred Stock 3,749 shares1,939,508 
N-Able Technologies International Inc.Common and Preferred Stock 166,860 shares1,852,146 
Aspen Technology Inc.Common and Preferred Stock 12,162 shares1,851,056 
Markel Corporation Holding CompanyCommon and Preferred Stock 1,490 shares1,838,660 
Altra Industrial Motion CorporationCommon and Preferred Stock 35,331 shares1,822,020 
WisdomTree Investments Inc.Common and Preferred Stock 296,463 shares1,814,354 
Fiverr International LimitedCommon and Preferred Stock 15,882 shares1,805,783 
Monro Inc.Common and Preferred Stock 30,940 shares1,802,874 
Barnes Group Inc.Common and Preferred Stock 37,826 shares1,762,313 
AptarGroup Inc.Common and Preferred Stock 14,315 shares1,753,301 
CarGurus Inc. Class ACommon and Preferred Stock 51,408 shares1,729,365 
Wolverine World Wide Inc.Common and Preferred Stock 59,278 shares1,707,799 
Canada Goose Holdings Inc.Common and Preferred Stock 46,015 shares1,705,316 
Omnicell Inc.Common and Preferred Stock 9,304 shares1,678,814 
Hexcel CorporationCommon and Preferred Stock 31,854 shares1,650,037 
WillScot Mobile Mini Holdings CorporationCommon and Preferred Stock 40,354 shares1,648,057 
CareDx Inc.Common and Preferred Stock 35,578 shares1,618,087 
Boston Properties Inc.Common and Preferred Stock 14,011 shares1,613,787 
II-Vi Inc.Common and Preferred Stock 23,504 shares1,606,028 
Herbalife Nutrition LimitedCommon and Preferred Stock 39,004 shares1,596,434 
Graphic Packaging Holding CompanyCommon and Preferred Stock 81,825 shares1,595,588 
Smartsheet Inc. Class ACommon and Preferred Stock 20,499 shares1,587,648 
Kraton CorporationCommon and Preferred Stock 33,505 shares1,551,954 
16



Schedule H, line 4i – Schedule of Assets (Held at End of Year) (continued)
Identity of IssueDescription of InvestmentCurrent Value
PacWest BancorpCommon and Preferred Stock 33,783 shares1,525,978 
ZipRecruiter Inc. Class ACommon and Preferred Stock 60,893 shares1,518,671 
Matthews International Corporation Class ACommon and Preferred Stock 41,315 shares1,515,021 
Under Armour Inc. Class CCommon and Preferred Stock 82,172 shares1,482,383 
Huron Consulting Group Inc.Common and Preferred Stock 29,649 shares1,479,485 
Pacific Premier Bancorp Inc.Common and Preferred Stock 36,368 shares1,455,811 
Tenable Holdings Inc.Common and Preferred Stock 26,236 shares1,444,817 
Cimpress plcCommon and Preferred Stock 20,090 shares1,438,645 
Privia Health Group Inc.Common and Preferred Stock 55,410 shares1,433,457 
Supernus Pharmaceuticals Inc.Common and Preferred Stock 48,989 shares1,428,519 
Teledyne Technologies Inc.Common and Preferred Stock 3,269 shares1,428,193 
IAA Spinco Inc.Common and Preferred Stock 28,207 shares1,427,838 
Kodiak Sciences Inc.Common and Preferred Stock 16,772 shares1,421,930 
Ciena CorporationCommon and Preferred Stock 18,365 shares1,413,554 
Prestige Consumer Healthcare Inc.Common and Preferred Stock 22,938 shares1,391,190 
Sumo Logic Inc.Common and Preferred Stock 102,451 shares1,389,236 
Knight-Swift Transportation Holdings Inc. Class ACommon and Preferred Stock 22,767 shares1,387,421 
Box Inc. Class ACommon and Preferred Stock 52,638 shares1,378,589 
Bank OzkCommon and Preferred Stock 29,614 shares1,377,939 
Nu Skin Enterprises Inc. Class ACommon and Preferred Stock 27,012 shares1,370,859 
JBG SMITH PropertiesCommon and Preferred Stock 47,542 shares1,364,931 
SLR Investment CorporationCommon and Preferred Stock 73,775 shares1,359,673 
IPG Photonics CorporationCommon and Preferred Stock 7,893 shares1,358,701 
Diamondback Energy Inc.Common and Preferred Stock 12,466 shares1,344,458 
Sportradar GroupCommon and Preferred Stock 75,738 shares1,330,717 
Encompass Health CorporationCommon and Preferred Stock 20,220 shares1,319,557 
Range Resources CorporationCommon and Preferred Stock 72,997 shares1,301,537 
Anaplan Inc.Common and Preferred Stock 28,078 shares1,287,376 
Mandiant Inc.Common and Preferred Stock 72,539 shares1,272,334 
BRP Group Inc. Class ACommon and Preferred Stock 35,112 shares1,267,894 
Nevro CorporationCommon and Preferred Stock 15,219 shares1,233,804 
Texas Pacific Land Corporation Common and Preferred Stock 978 shares1,221,395 
KnowBe4 Inc. Class ACommon and Preferred Stock 52,912 shares1,213,801 
Texas Capital Bancshares Inc.Common and Preferred Stock 19,836 shares1,195,119 
Berkshire Hills Bancorp Inc.Common and Preferred Stock 41,230 shares1,172,169 
Arvinas Inc.Common and Preferred Stock 14,241 shares1,169,756 
Coherus BioSciences Inc.Common and Preferred Stock 73,238 shares1,168,878 
Abiomed Inc.Common and Preferred Stock 3,236 shares1,162,274 
Relay Therapeutics Inc.Common and Preferred Stock 37,423 shares1,149,260 
AZZ Inc.Common and Preferred Stock 20,736 shares1,146,493 
Fox Factory Holding CorporationCommon and Preferred Stock 6,632 shares1,128,103 
Sterling Check CorporationCommon and Preferred Stock 53,897 shares1,105,427 
Agios Pharmaceuticals Inc.Common and Preferred Stock 33,477 shares1,100,389 
TreeHouse Foods Inc.Common and Preferred Stock 26,684 shares1,081,503 
John Bean Technologies CorporationCommon and Preferred Stock 7,042 shares1,081,370 
Evercore Inc.Common and Preferred Stock 7,954 shares1,080,551 
Alamos Gold Inc. Class ACommon and Preferred Stock 139,767 shares1,074,808 
World Wrestling EntertainmentCommon and Preferred Stock 21,661 shares1,068,754 
Vroom Inc.Common and Preferred Stock 98,021 shares1,057,647 
Cooper Companies Inc.Common and Preferred Stock 2,482 shares1,039,809 
17



Schedule H, line 4i – Schedule of Assets (Held at End of Year) (continued)
Identity of IssueDescription of InvestmentCurrent Value
Solarwinds CorporationCommon and Preferred Stock 71,697 shares1,017,380 
Farfetch Limited Class ACommon and Preferred Stock 30,231 shares1,010,622 
Heron Therapeutics Inc.Common and Preferred Stock 110,570 shares1,009,504 
Consensus Cloud Solutions Inc. Common and Preferred Stock 17,412 shares1,007,632 
Polaris Inc.Common and Preferred Stock 9,154 shares1,006,116 
C4 Therapeutics Inc. Common and Preferred Stock 31,127 shares1,002,289 
Shutterstock Inc.Common and Preferred Stock 8,977 shares995,370 
1-800-FLOWERS.COM Inc. Class ACommon and Preferred Stock 41,874 shares978,595 
Albemarle CorporationCommon and Preferred Stock 4,184 shares978,094 
SpringWorks Therapeutics Inc.Common and Preferred Stock 15,422 shares955,856 
Axogen Inc.Common and Preferred Stock 101,418 shares950,287 
Cal/Maine Foods Inc.Common and Preferred Stock 24,349 shares900,670 
Cano Health Inc. Class A Common and Preferred Stock 100,183 shares892,631 
iShares Core S&P Small-Cap ETFMutual Fund 7,631 units873,826 
United Community Bank Blairsville GeorgiaCommon and Preferred Stock 23,216 shares834,383 
Exact Sciences CorporationCommon and Preferred Stock 10,696 shares832,470 
Designer Brands Inc. Class ACommon and Preferred Stock 58,536 shares831,797 
KB HomeCommon and Preferred Stock 18,474 shares826,342 
NorthWestern CorpCommon and Preferred Stock 13,804 shares789,037 
Heartland Express Inc.Common and Preferred Stock 45,509 shares765,461 
Flowserve CorporationCommon and Preferred Stock 24,786 shares758,452 
Xperi Holding CorporationCommon and Preferred Stock 38,238 shares723,081 
Mercury Systems Inc.Common and Preferred Stock 13,074 shares719,854 
Viking Therapeutics Inc.Common and Preferred Stock 156,336 shares719,146 
WSFS Financial CorporationCommon and Preferred Stock 14,312 shares717,317 
Infinera CorporationCommon and Preferred Stock 73,824 shares707,972 
CalAmp CorporationCommon and Preferred Stock 98,951 shares698,594 
PetIQ Inc. Class ACommon and Preferred Stock 30,430 shares691,065 
Silgan Holdings Inc.Common and Preferred Stock 14,984 shares641,915 
Banner CorporationCommon and Preferred Stock 10,265 shares622,778 
iShares Russell Mid-Cap ETFMutual Fund 7,335 units608,878 
Haemonetics CorporationCommon and Preferred Stock 11,201 shares594,101 
Oceaneering International Inc.Common and Preferred Stock 50,327 shares569,198 
STAG Industrial Inc.Common and Preferred Stock 11,201 shares537,200 
NexTier Oilfield Solutions Inc.Common and Preferred Stock 148,086 shares525,705 
iShares Russell 2000 ETFMutual Fund 2,104 units468,035 
Alight Inc. Class ACommon and Preferred Stock 39,442 shares426,368 
eHealth Inc.Common and Preferred Stock 16,236 shares414,018 
J & J Snack Foods CorporationCommon and Preferred Stock 1,958 shares309,286 
Talis Biomedical CorporationCommon and Preferred Stock 53,052 shares212,739 
Total U.S. Equity Asset Class1,714,872,738 
U.S. Equity Index Asset Class:
NT Collective Russell 3000 Index Fund / Non Lending*Collective Trust Fund 13,250,686 units975,793,781 
Gaming & Leisure Properties Inc.Common and Preferred Stock 155 shares7,542 
CTO Realty Growth Inc.Common and Preferred Stock 82 shares5,036 
NT Collective Short Term Investment Fund*Collective Trust Fund 235 units234 
18



Schedule H, line 4i – Schedule of Assets (Held at End of Year) (continued)
Identity of IssueDescription of InvestmentCurrent Value
Total U.S. Equity Index Asset Class975,806,593 
International Equity Class:
Mawer International Equity Collective Investment Trust Class B*Collective Trust Fund 7,906,966 units142,493,012 
Polaris Capital Management Collective Investment Trust International Value Collective Fund*Collective Trust Fund 11,549,975 units136,685,875 
Reliance Trust Institutional Retirement Trust GQG Partners International Equity Fund Series 11 Class C*Collective Trust Fund 7,951,753 units110,131,779 
Wilmington Trust Collective Investment Trust / Jennison International Equity Opportunities CIT Class J*Collective Trust Fund 6,849,549 units83,701,490 
Dodge & Cox International FundMutual Fund 1,690,348 units79,936,563 
NT Collective MSCI All Country World Index (ACWI) ex/US Index Fund / Non Lending*Collective Trust Fund 204,987 units44,875,034 
Interest Bearing CashCash and Cash Equivalents 8,482 units8,482 
Total International Equity Asset Class597,832,235 
International Equity Index Asset Class:
NT Collective All Country World Index (ACWI) Ex/US Fund / Non Lending*Collective Trust Fund 2,349,363 units469,637,570 
BlackRock FTSE RAFI Emerging Index Non Lendable Fund F*Collective Trust Fund 21,268 units98,297 
Total International Equity Index Asset Class469,735,867 
Participant Self-Directed AccountsVarious Investments781,940,783 
781,940,783 
Notes Receivable from Participants*Interest Rate 4.25% - 9.25%30,243,936 
30,243,936 
Other:
BIF Money Fund*Cash and Cash Equivalents 3,043,753 units3,043,753 
Vanguard Federal Money MarketCash and Cash Equivalents 498,898 units498,898 
NT Collective Short Term Investment Fund*Collective Trust Fund 303,581 units303,581 
Exide TechnologiesCommon and Preferred Stock 35,683 shares24,978 
Exide Technologies 144A 11.0% Due 05/24/2017Corporate Bond 9,077 units78 
Total Other3,871,288 
Grand Total$7,183,734,301 
* Indicates party-in-interest

19


Supplemental Schedule
Amgen Retirement and Savings Plan
EIN: 95-3540776 Plan: #001
Year Ended December 31, 2021
Schedule H, line 4i – Schedule of Assets (Acquired and Disposed of Within Year)
Identity of IssueDescription of InvestmentProceeds from Dispositions
Participant Self-Directed Brokerage AccountsVarious Investments$33,444 
20


Supplemental Schedule
Amgen Retirement and Savings Plan
EIN: 95-3540776 Plan Number: #001
As of December 31, 2021
Schedule G, Part 1 – Schedule of Loans or Fixed Income Obligations
in Default or Classified as Uncollectible
Identity of obligorOriginal
amount of
loan
(cost of
security)
Unpaid balance
at end of year
(fair value of
security)
Detailed description of loan including dates of making and maturity, interest rate, the type and value of collateral, any renegotiation of the loan and the terms of the renegotiation and other
material items (description of fixed income obligation)
Amount of
principal
overdue
Amount of
interest
overdue
Kaupthing Bank$183,033 $775 Corporate Bonds 310,000 units due 2/28/2020$310,000 $— 

21


Supplemental Schedule
Amgen Retirement and Savings Plan
EIN: 95-3540776 Plan Number: #001
Year Ended December 31, 2021
Schedule H, line 4a — Schedule of Delinquent Participant Contributions

Participant Contributions Transferred Late to PlanTotal that Constitute Nonexempt Prohibited Transactions
Check Here if Late Participant Loan Repayments are Included: ☐Contributions Not Corrected
Contributions Corrected Outside VFCP1
Contributions Pending Corrections in VFCP1
Total Fully Corrected Under VFCP1 and PTE2 2002-51
$17,793 $— $17,793 $— $— 

Note: In 2021, the Company failed to timely remit certain participant contribution deferrals in accordance with Department of Labor regulations. The Company has calculated and remitted lost earnings with respect to such deferrals and is in the process of filing Form 5330, “Return of Excise Taxes Related to Employee Benefit Plans.”

________
1Voluntary Fiduciary Correction Program
2Prohibited Transaction Exemption
22


AMGEN RETIREMENT AND SAVINGS PLAN
INDEX TO EXHIBIT
 
23


SIGNATURES
Pursuant to the requirements of the Securities Exchange Act of 1934, the trustees (or other persons who administer the employee benefit plan) have duly caused this annual report to be signed on its behalf by the undersigned hereunto duly authorized.
  
 Amgen Retirement and Savings Plan
 (Name of Plan)
Date:June 23, 2022 By: /s/ PETER H. GRIFFITH
   
Peter H. Griffith
   
Executive Vice President and
Chief Financial Officer
Amgen Inc.
24
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