RNS Number:3512P
Clinical Computing PLC
3 September 2003


                  DEALINGS BY SUBSTANTIAL SHAREHOLDERS


1)   NAME OF COMPANY

     CLINICAL COMPUTING PLC

2)   NAME OF SHAREHOLDER HAVING A MAJOR INTEREST

     SECOND ADVANCE VALUE REALISATION COMPANY LIMITED

3)   Please state whether notification indicates that it is in respect of 
     holding of the Shareholder named in 2 above or in respect of a 
     non-beneficial interest or in the case of an individual holder if it is a
     holding of that person's spouse or children under the age of 18

     SHAREHOLDER

4)   Name of the registered holder(s) and, if more than one holder, the 
     number of shares held by each of them.



5)   Number of shares/amount of stock acquired.



6)   Percentage of issued Class



7)   Number of shares/amount of stock disposed

     500,000

8)   Percentage of issued Class

     1.99%

9)   Class of security

     ORDINARY 5p

10)  Date of transaction

     1 SEPT 2003

11)  Date company informed

     3 SEPT 2003

12)  Total holding following this notification

     1,235,000
               
13)  Total percentage holding of issued class following this notification

     4.92%

14)  Any additional information



15)  Name of contact and telephone number for queries

     JOSEPH MARLOVITS
     020 8747 8744

16)  Name and signature of authorised company official responsible for 
     making this notification

     Date of Notification ....3 SEPT 2003....



                  DEALINGS BY SUBSTANTIAL SHAREHOLDERS


1)   NAME OF COMPANY

     CLINICAL COMPUTING PLC

2)   NAME OF SHAREHOLDER HAVING A MAJOR INTEREST

     SECOND ADVANCE VALUE REALISATION COMPANY LIMITED

3)   Please state whether notification indicates that it is in respect of 
     holding of the Shareholder named in 2 above or in respect of a 
     non-beneficial interest or in the case of an individual holder if it is a
     holding of that person's spouse or children under the age of 18

     SHAREHOLDER

4)   Name of the registered holder(s) and, if more than one holder, the 
     number of shares held by each of them.



5)   Number of shares/amount of stock acquired.



6)   Percentage of issued Class



7)   Number of shares/amount of stock disposed

     70,000

8)   Percentage of issued Class

     0.22%

9)   Class of security

     ORDINARY 5p

10)  Date of transaction

     2 SEPT 2003

11)  Date company informed

     3 SEPT 2003

12)  Total holding following this notification

     1,165,000
               
13)  Total percentage holding of issued class following this notification

     3.70%

14)  Any additional information



15)  Name of contact and telephone number for queries

     JOSEPH MARLOVITS
     020 8747 8744

16)  Name and signature of authorised company official responsible for 
     making this notification

     Date of Notification ....3 SEPT 2003....



                  DEALINGS BY SUBSTANTIAL SHAREHOLDERS


1)   NAME OF COMPANY

     CLINICAL COMPUTING PLC

2)   NAME OF SHAREHOLDER HAVING A MAJOR INTEREST

     SECOND ADVANCE VALUE REALISATION COMPANY LIMITED

3)   Please state whether notification indicates that it is in respect of 
     holding of the Shareholder named in 2 above or in respect of a 
     non-beneficial interest or in the case of an individual holder if it is a
     holding of that person's spouse or children under the age of 18

     SHAREHOLDER

4)   Name of the registered holder(s) and, if more than one holder, the 
     number of shares held by each of them.



5)   Number of shares/amount of stock acquired.



6)   Percentage of issued Class



7)   Number of shares/amount of stock disposed

     600,000

8)   Percentage of issued Class

     1.90%

9)   Class of security

     ORDINARY 5p

10)  Date of transaction

     3 SEPT 2003

11)  Date company informed

     3 SEPT 2003

12)  Total holding following this notification

     565,000
               
13)  Total percentage holding of issued class following this notification

     1.79%

14)  Any additional information



15)  Name of contact and telephone number for queries

     JOSEPH MARLOVITS
     020 8747 8744

16)  Name and signature of authorised company official responsible for 
     making this notification

     Date of Notification ....3 SEPT 2003....


                      This information is provided by RNS
            The company news service from the London Stock Exchange

END
HOLEASNDEEEDEFE