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Iovance Biotherapeutics Inc

Iovance Biotherapeutics Inc (IOVA)

11.64
0.10
(0.87%)
Closed April 27 4:00PM
11.63
-0.01
(-0.09%)
After Hours: 7:54PM

Calls

StrikeBid PriceAsk PriceLast PriceMidpointChangeChange %VolumeOPEN INTLast Trade
6.500.000.000.000.000.000.00 %00-
7.004.207.000.005.600.000.00 %00-
7.503.706.500.005.100.000.00 %00-
8.000.000.000.000.000.000.00 %00-
8.500.000.000.000.000.000.00 %00-
9.000.000.000.000.000.000.00 %00-
9.500.000.000.000.000.000.00 %00-
10.000.000.000.000.000.000.00 %00-
10.500.552.700.001.6250.000.00 %00-
11.000.000.000.000.000.000.00 %00-
11.500.000.000.000.000.000.00 %00-
12.000.050.400.300.2250.1050.00 %791284/26/2024
12.500.000.000.000.000.000.00 %00-
13.000.050.100.100.075-0.05-33.33 %122144/26/2024
13.500.000.000.000.000.000.00 %00-
14.000.000.000.000.000.000.00 %00-
14.500.050.600.060.325-0.04-40.00 %11,1104/26/2024
15.000.100.750.100.4250.000.00 %0160-
15.500.000.000.000.000.000.00 %00-
16.000.000.000.000.000.000.00 %00-

Puts

StrikeBid PriceAsk PriceLast PriceMidpointChangeChange %VolumeOPEN INTLast Trade
6.500.001.750.000.000.000.00 %00-
7.000.000.000.000.000.000.00 %00-
7.500.000.000.000.000.000.00 %00-
8.000.000.000.000.000.000.00 %00-
8.500.000.000.000.000.000.00 %00-
9.000.000.750.000.000.000.00 %00-
9.500.000.000.000.000.000.00 %00-
10.000.000.000.000.000.000.00 %00-
10.500.000.000.000.000.000.00 %00-
11.000.000.000.000.000.000.00 %00-
11.500.300.400.350.350.1040.00 %48124/26/2024
12.000.500.700.600.600.0917.65 %61414/26/2024
12.500.000.000.000.000.000.00 %00-
13.000.000.000.000.000.000.00 %00-
13.501.203.901.622.550.000.00 %08-
14.000.000.000.000.000.000.00 %00-
14.502.455.501.533.9750.000.00 %00-
15.000.000.000.000.000.000.00 %00-
15.503.406.500.004.950.000.00 %00-
16.004.207.000.005.600.000.00 %00-

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IOVA Discussion

View Posts
surfkast surfkast 22 hours ago
LOL! I am basically self taught with computers and all. GLTY
๐Ÿ‘๏ธ0
badgerkid badgerkid 1 day ago
Surfkast, thank you. Looks like 40 ATC's at this time. The company stated 50 by the end of May. Looks to be on track.

Looks like I just needed to keep clicking on the "LOAD MORE" button on the search page to add in the rest of the centers after plugging in my zip.

I'm not the sharpest tool (but I am a tool or so I've been told).
๐Ÿ‘๏ธ0
surfkast surfkast 1 day ago
I see the following are listed on the website.

Memorial Sloan Kettering Cancer Center
51.0 Miles

1275 York Ave

New York, NY 10065

646-608-2091
Smilow Cancer Hospital-Yale New Haven
80.8 Miles

20 York St

New Haven, CT 06510

203-200-CART
Cooper University Healthcare
83.7 Miles

1 Cooper Plz

Camden, NJ 08103

855-632-2667
Thomas Jefferson University Hospital
84.6 Miles

111 S 11th St

Philadelphia, PA 19107

215-955-8874
University of Maryland Medical Center
172.4 Miles

22 S Greene St

Baltimore, MD 21201

410-328-7609
Dana-Farber Brigham Cancer Center
184.9 Miles

450 Brookline Ave

Boston, MA 02215

877-442-3324
Massachusetts General Cancer Center
187.5 Miles

55 Fruit St

Boston, MA 02114

617-724-4000
MedStar Georgetown University Hospital
207.8 Miles

3800 Reservoir Rd., NW

Washington, DC 20007

202-993-0492
Roswell Park Comprehensive Cancer Center
281.8 Miles

665 Elm St

Buffalo, NY 14203

716-845-2300
West Penn Hospital
307.3 Miles

4800 Friendship Ave

Pittsburgh, PA 15224

412-578-4484
The Cleveland Clinic Foundation
392.9 Miles

9500 Euclid Ave

Cleveland, OH 44195

216-445-5600
Duke University Hospital
425.6 Miles

2400 Pratt Street

Durham, NC 27705

919-684-7115
The Ohio State University Wexner Medical Center, James Cancer Hospital
472.5 Miles

460 W 10th Ave

Columbus, OH 43210

614-293-3153
The University of Tennessee Medical Center
631.8 Miles

1924 Alcoa Hwy

Knoxville, TN 37920

865-305-5003
Brown Cancer Center, University of Louisville
645.3 Miles

529 South Jackson

Louisville, KY 40202

502-562-4673
University of Chicago Medicine
702.4 Miles

5841 S Maryland Ave

Chicago, IL 60637

773-702-1994
Northwestern Memorial Hospital
703.4 Miles

251 E Huron Street

Chicago, IL 60611

312-695-0990
Froedtert & the Medical College of Wisconsin Cancer Network
729.6 Miles

8800 W. Doyne Ave.

Milwaukee, WI 53226

414-805-0505
Northside Hospital
739.4 Miles

1000 Johnson Ferry Rd NE

Atlanta, GA 30342

404-255-1930
Mayo Clinic Florida
840.4 Miles

4500 San Pablo Rd S

Jacksonville, FL 32224

904-953-0863
Barnes-Jewish Hospital
870.8 Miles

One Barnes-Jewish Hospital Plaza

Saint Louis, MO 63110

314-454-8304
UF Health Shands Hospital
904.1 Miles

1535 Gale Lemerand Drive

Gainesville, FL 32610

352-265-0725
University Of Iowa Hospitals And Clinics
905.9 Miles

200 Hawkins Dr

Iowa City, IA 52242

319-356-1616
Orlando Health Cancer Institute
947.1 Miles

1400 S Orange Ave

Orlando, FL 32806

321-841-1893
Mayo Clinic - Rochester
958.8 Miles

200 1st St SW

Rochester, MN 55901

507-538-3270
Moffitt Cancer Center
1002.7 Miles

12902 USF Magnolia Drive

Tampa, FL 33612

888-663-3488
The University of Kansas Cancer Center
1090.5 Miles

4000 Cambridge St

Kansas City, KS 66160

913-588-9187
Nebraska Medicine
1136.7 Miles

505 S 45th Street

Omaha, NE 68105

402-559-5600
Avera Cancer Institute
1167.8 Miles

1000 E 21st Street

Sioux Falls, SD 57105

888-422-1410
Baylor Scott & White Charles A. Sammons Cancer Center
1367.5 Miles

3410 Worth St

Dallas, TX 75246

214-370-1550
Houston Methodist Hospital
1421.2 Miles

6445 Main St

Houston, TX 77030

713-441-9946
MD Anderson
1421.4 Miles

1515 Holcombe Blvd

Houston, TX 77030

713-745-0940
Huntsman Cancer Institute - University of Utah
1957.0 Miles

2000 Circle Of Hope Dr

Salt Lake City, UT 84112

801-587-4652
Honorhealth Research Institute
2121.0 Miles

10510 N 92nd Street

Scottsdale, AZ 85258

480-323-1364
Mayo Clinic Hospital
2122.6 Miles

5777 E Mayo Blvd

Phoenix, AZ 85054

480-301-8484
City of Hope National Medical Center
2423.3 Miles

1500 E Duarte Rd

Duarte, CA 91010

1-800-826-4673
OHSU Hospital
2430.5 Miles

3181 SW Sam Jackson Park Rd

Portland, OR 97239

503-494-5058
Ronald Reagan UCLA Medical Center
2449.8 Miles

757 Westwood Plz

Los Angeles, CA 90095

888-ONC-UCLA
UCLA Santa Monica Medical Center
2453.0 Miles

1250 16th St

Santa Monica, CA 90404

888-ONC-UCLA
Stanford Health Care
2554.1 Miles

300 Pasteur Dr

Stanford, CA 94305

650-498-6000 (promp
๐Ÿ‘๏ธ0
badgerkid badgerkid 2 days ago
Motley article today: "3 Millionaire-Maker Biotech Stocks" "...As veteran investors can attest, however, the time to go shopping is when quality stocks are discounted. With that as the backdrop, here's a rundown on three biotech stocks you may want to consider scooping up while they're still on sale..."

https://finance.yahoo.com/news/3-millionaire-maker-biotech-stocks-143000558.html

It's another MF teaser article to entice a further look at MF. It's click bait if you will, but it's nice to be on the positive side of an article. Let's see if the cycle continues right up to the Q1 call.

Good luck to the longs.
๐Ÿ‘๏ธ0
badgerkid badgerkid 2 days ago
Does anyone have an updated list of the ATC's for Amtagvi? I recently saw that Froedtert in Milwaukee was placed on the list and I believe Iovance has more than 40 approved.

An actual list would be greatly appreciated. Share if you can.

Thanks.

https://www.amtagvi.com/support-and-resources/authorized-treatment-center/
๐Ÿ‘๏ธ0
badgerkid badgerkid 2 days ago
MN Gopher, as we've discussed many times, the one thing I take comfort in with Iovance is the group of investors that have come together and own a significant portion of this company. Those same investors have a proven track record of making good decisions and ensuring the companies' management teams and key employees can serve the overall needs of those companies, and by extension ensure a good return on their investments.

My belief is they see and know far more than any of us here and yet they've continued to add to their stock positions.

We're in good company with this group of investors and the team at Iovance.

And again, thanks for the recommendation of the book "For Blood and Money" It's a good read and an inside look at one of Iovance's biggest investors - Wayne Rothbaum. More interesting to me is some of the inside looks at the actual scientists and financiers and that whole relationship in setting up some of these biopharm companies.

Badgerkid
๐Ÿ‘๏ธ0
MN Gopher MN Gopher 2 days ago
Well said Badger, IBRX seems to be alot of
Background โ€œnoiseโ€ all over message boards filling it with lies & innuendo

Iovance is rock solid and all the major ITCโ€™S opening, IE: Mayo Clinic, MD Anderson(multiple locations)
Duke U, ETC shows just how promising our treatment is for Melanoma & I suspect many other solid tumor applications on the horizon.

Ignore the noise & add shares on these crazy dips, in my opinion.

#CureCancer
๐Ÿ‘๏ธ0
badgerkid badgerkid 2 days ago
Sunman, regarding the nonsense that surrounded the ticker IBRX, it seems a small handful of posters, or one with multiple aliases was running a pump and dump - not very effectively, but that's how it seemed. I don't know if it's a good or mediocre play, but I do know the comparisons that were being made by that small group of noise makers are blatant lies and misinformation. Many of the posters on that board have also grown tired of that incessant nonsense as it didn't help in having a true and detailed conversation about their investment in that company. I use message boards to encourage me to dig a little deeper when I hear something that raises a question or a point of value.

Agreed, it's only noise and nonsense, but I assume it did and does have an effect on some retail investors. Hey, it got me to look if only briefly, but that's what I require of myself to know that I'm doing my due diligence on IOVA.

I've done my due diligence and I have high confidence in my IOVA investment. Amtagvi has the potential to get Iovance into the black by the end of next year (a "blockbuster" therapy of sorts) because of the team at Iovance that's bringing it to market. I do not own any of that other company, but I can't say if it should or should not be considered.

Like I said before, an approved drug or therapy is only part of the equation, even if it has potential of blockbuster status, getting it to market and prescribed by the medical community is "a whole nother thing" (my idiom for today).

Good luck to the Iovance investors, it would seem we have a blockbuster therapy and a winning team running the company.
👍️ 1
retired early retired early 2 days ago
Yes I do have the time and while waiting, I do fill pot holes here and there. :)
๐Ÿ‘๏ธ0
Sunman88 Sunman88 2 days ago
People are getting confused about Anktiva approval and are drawing thoughtless comparisons to Amtagvi.
Lots of nonsense being discussed on Yahoo mb under IBRX ticker.

Post from yahoo;
Lifleucel costs 500 k and response is 31%. Anktiva in melanoma had 68% response , same with pancreatic cancer and solid tumors. Medicare will not pay for 500 k. It will say, keytruda failed? Then itโ€™s chemo and radiation. End of story. Just real world facts.
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surfkast surfkast 2 days ago
Not an expert on biopharmaceutical companies by any means but this does look good for IOVA. Maybe they will be getting more attention.
๐Ÿ‘๏ธ0
badgerkid badgerkid 3 days ago
I'm telling you GMH, the Iovance management team seems to have it together. It's one thing to have a workable therapy or successful drug, but there's far more to making it profitable and building the value of a company.

A very good combination indeed.

Another thank you has to go out to my friend who told me to check Iovance out after he had been watching it for several years. I was intrigued by TIL therapy, the approval was awesome, but it's the team at Iovance that has me hanging on to a core position of shares.

Best of luck to you GMH.
๐Ÿ‘๏ธ0
GMH* GMH* 3 days ago
Just saw this.... this is why I do not jump in-and-out on biotechs. You never know when an "unexpected" catalyst will happen. Usually these are poster presentations so its good to see they got a spot for an oral presentation... guessing the data from cohort 1A is pretty good to warrant that.
👍️ 2
badgerkid badgerkid 3 days ago
Iovance will be presenting at the ASCO: "Oral Presentation of Updated Results of IOV-COM-202 Cohort 1A of Lifileucel plus Pembrolizumab in Advanced Frontline Melanoma"

https://ir.iovance.com/news-releases/news-release-details/iovance-biotherapeutics-present-clinical-and-translational-data
👍️ 2
badgerkid badgerkid 4 days ago
Retired early, it's definitely on the road, but there's still a few pot holes that need to be filled in.

I'm anticipating a very good call at the Q1, but I'm not certain how it will effect share price just yet since actual revenue won't show up until the Q2 report.
Since you retired early, I'm assuming you have some time.

Good luck to you.
👍️ 1
retired early retired early 4 days ago
Let's get this show on the road. :)
๐Ÿ‘๏ธ0
surfkast surfkast 4 days ago
Updates on analysist ratings show this to still be a buy to a strong buy. Looks like the 2024 target is $26.00,
👍️ 1
MN Gopher MN Gopher 5 days ago
Your welcome Surkast
👍️ 1
Sunman88 Sunman88 6 days ago
In my opinion, this is not the time to dump. iThe time was between $15-17. My guidance is to hold on to a core position and accumulate at levels under where we are today. You may always sell some now or wait until itโ€™s above $15 when the time comes in a few months. Long term view in 1-2 years, IOVA gets bought out above $30-40 as sales trajectory confirms $1B trajectory and confirmatory trial is positive. Iโ€™m betting on this scenario to take hold. Of course if NSCLC trial is positive, the value improves further.
I believe in this technology and also believe as healthier patients become eligible the it desirable outcomes will only improve.
👍️ 1
surfkast surfkast 6 days ago
Thanks for the link.
👍️ 1
surfkast surfkast 6 days ago
There are 5 moderator spots open. I will be here.
👍️ 2
MN Gopher MN Gopher 6 days ago
https://www.cancernetwork.com/view/tumor-infiltrating-lymphocyte-therapy-advances-into-melanoma

Mabye this article will
Help you make an informed decision.

I am an Amateur Self Taught Investor & do not give financial advise who is all in with Iovance. It represents an opportunity in my opinion equivalent buying when Apple One IPhone Arrived.
The rest is history.

We are in our infancy & in the next 10 years, we will rewrite Cancer Treatment Therapies For Use In Humans To Help Cure Cancer & License our Technology to other BP of BioPharm.

As we MN Gophers like to say: Row The Boat

Just wanted to wish you well in your retirement & to encourage you to give it great thought & patience.

In my opinion, it will help fund your retirement one dayโ€ฆ.

Good Luck
👍️ 1
MN Gopher MN Gopher 6 days ago
GMH, The link article was enlightening to read exactly what we talk about here.

This is square one of a long marathon in TIL Therapy For Curing Cancer & who knows, mabye other diseases along the way.

This company is for me as an investor, finding the Pot of Gold for lack of a better analogy.

Thank you for sharing. Exceptional confirmation for all to read this must read link.

#CureCancer
๐Ÿ‘๏ธ0
MN Gopher MN Gopher 6 days ago
GMH, Thanks for finding my error. Confusion on the end of 1st Qtr.
The numbers I posted are for the 2nd & 3rd Qtrโ€™s.

I did post the high end of the spectrum, Im an eternal optimist with Iovance.

I follow the Science & The $ in something like Amtagvi. The top Biotech Investor in our lifetimes is in charge of Iovance & knows EXACTLY what it takes to execute the game plan in real time.

In my opinion, we are blessed beyond comprehension with Wayne leading the charge in helping to Cure Cancer & Find us a Triple Figure Buyout.

Wayne will not make any mistakes in our sale & valuation. He is The Best in the Business.

The Science is what 35-40 years old with Stephen A. Rosenberg being Ground Zero in his steadfast belief Solid Tumor Cancer Tumors could be Cured (Partial Cures too, my addition)

https://ccr.cancer.gov/staff-directory/steven-a-rosenberg

We have to me Apple One equivalent
The beginning of a life transforming Treatment that will be improved upon, Licensed to other BP or BioTech Companies to continue on humanities quest to Cure Cancer.

We will use genetic modifications to possibly improve upon our treatments.

This in theory translate to โ€œCureโ€ many other Solid Tumor Applications, World Wide. We will in my opinion be FDA Approved one day for many, many solid tumor applications.

We will move to front line in my opinion soon on Melanoma combining Amtagvi with Keytruda.
Our stats show together in Phase 3 study, 66.7% in combo.
This alone crushes our 31.4 Amtagvi FDA accelerated approval for last line of D in use today, alone without Keytruda.

Think Merck: Keytruda Exclusivity ends in 2028. This is their Cash Cow.
Imagine Merck buying Iovance (in 2025/26 in my opinion) n extending Keytrudaโ€™s Exclusivity useage piggybacking with Amtagvi Treatments. Iovance with its approved 4 Yr exclusivity extension at the end of their 14 yr exclusivity tagteams them to 2042!

This company is now in say the equivalent
Of a 10 month old kid.

Its the beginning of a world wide expansion for TIL/Amtagvi in Clinical/ Hospital Use in their own ATCโ€™S.

Wayne Rothbaum is a special Biotech investor man. He has long term relationships in Biotech & Buyouts well established prior to Iovance.

His expertise & relationships tell me one thing: Think Acerta & We Are Up Next.

Im adding as many shares at every dip I can.

#CureCancer
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badgerkid badgerkid 6 days ago
Surfkast, I understand your frustration especially given what you've shared with us on this board about your current point in your life. We each have to follow our own path. Good advice that I received from a very successful friend - there's 100's of reasons to sell a stock and only one reason to buy it. No one here can tell you what to do, but I do appreciate your willingness to be board monitor. Timing is not always our friend.

Do you think it would be advisable for one of us to take on the role of monitor? I do think we're going to start seeing a lot more posters on this site in the coming months.

All my best to you no matter what you decide.

Good luck to you throughout your retirement years.

Badgerkid
👍️ 1
surfkast surfkast 6 days ago
I may dump Monday.
๐Ÿ‘๏ธ0
Sunman88 Sunman88 6 days ago
Always be grateful for what we have as things can get a lot worse. Badgerkid has nicely explained my POV.
I started adding at 11.80 and will
add more as it keeps trending lower. Putin and Iran are in collaboration to stir up trouble in the world to divert attention away from Ukraine and interfere with US elections. They are driving oil prices up so you and I (the average American) get pissed off as our stocks sink lower and uncertainty looms. With inflation not cooling, interest rate cuts will not happen anytime soon. IOVA has only one way to buck the market downtrend. Deliver news about high adoption rate and positive progress with confirmatory phase 3 trial. Any good news with NSCLC study will be icing. I wonโ€™t be surprised if SP goes even lower to $10. Not worried though as Iโ€™m positive it will buck the trend soon enough and also overall markets likely to rally around September. Enjoying some sunshine and breathing fresh air out in the mountains. Shish kebabs, tszaziki and grilled vegetables for dinner with sips of Old Fashioned Kentucky Bourbon and tipsy cherrries. Stay positive and enjoy the journey no matter what comes at you. Best wishes and Warm Regards.
👍️ 2
badgerkid badgerkid 7 days ago
GMH, thanks for your updates this morning. Enjoyed the articles and the shared info.

Truly appreciate what you've provided to me and to this board.

Badgerkid
๐Ÿ‘๏ธ0
badgerkid badgerkid 7 days ago
Neptune, I'm currently only using the free service to post on iHub, I'm not currently a paid subscriber so I can't respond to private messages except during the one hour free period on Fridays.

To answer your question, I got a tip last year to check out Iovance by a friend who had been paying attention to it for several years. He said it was time to give it a more serious look as they were close to a possible approval. I did some due diligence, took a small position in May of last year, went through a few ups and downs with the various issues and delays, sold a few shares on some ups and bought a few shares again. Then it dropped down into the $3's and I wondered what I had gotten myself into. After that, I did a lot more due diligence and realized the reasons to own this stock were valid and started to build a much bigger position but at prices around $7 or higher, not when it was down in the $3's (dang).

I've now built a nice core position which I will hang onto for what should prove to be a very good ride upwards over the coming months and years if the company continues to execute on its plan. I will try to stay flexible enough in case I see any concerns, but so far the only real issues that we seem to be currently facing are overall market conditions and negative sector sentiment at this time.

Amtagvi approval cemented my reasons to stay long and to further build my position, I continue to stay long because Iovance's management team has proven itself through each of the steps they've taken in being prepared for each contingency and how they hit the ground running with the Amtagvi approval.

Iovance's bigger shareholders are known to be very successful in their investments when they take large positions in companies and I expect Iovance will be one more success on their lists. I don't mind following the leaders, and the individual that shared this lead with me also has a proven track record.

Finally, I tend to get a little impatient, but the advice I've gotten from others who know this arena and have proven themselves, including several posters on this board, remind me that earnings are the driving force for the stock price at this time along with additional TIL therapy approvals and new foreign markets for Iovance's products. I expected a bigger jump on Amtagvi approval, but the market will reward us handsomely on IOVA when revenues start hitting the bottom line. IOVA is still trading at a higher price than the pre-approval price, even following the secondary offering, but the sector has not been our friend over this past month and there's been no news to add to the story.

When Q2, Q3, Q4 and 2025 guidance are available for viewing, we should gain continual price support. If the market doesn't get ahead of the actual numbers, it should be a nice ride. If the biotech sector sentiment makes a turn to the positive again, that should also help the upside during those quiet news periods.

I would like to hear your story if you're willing to share. What brought you over to this board? Invited or did you just stumble onto this motley crew? How long have you been invested in IOVA (assuming you are)?

Good luck to you.

Badgerkid
๐Ÿ‘๏ธ0
GMH* GMH* 7 days ago
Another interesting article published yesterday. Should not that Angeles Clinic and Research Institute is currently NOT an ATC.

https://www.cancernetwork.com/view/tumor-infiltrating-lymphocyte-therapy-advances-into-melanoma

Another article from Oncologist at Cooper Health (NJ). They are both a P3 trial site and also recently approved ATC. Comments are interesting in that I was concerned about P3 cannibalizing Commercial patients, but as noted, eligibility requirements probably will limit that. This is unfortunate for patients and hopefully patients will become aware of TIL prior to ICI treatment in the future, but for now, at least there is an L2+ option.

https://www.roi-nj.com/2024/04/18/healthcare/til-then-cooper-doctor-is-excited-to-bring-novel-melanoma-treatment-to-south-jersey-region/
👍️ 1
GMH* GMH* 7 days ago
On the Corporate Update deck, they said approximately 50 ATCs 90 days after approval so that would be end of May. They are now at 37 as Duke Medical in NC was added late Friday (4/19). I think 50 will not be too difficult, especially if other Cancer Centers are asking to become ATCs.
👍️ 1
GMH* GMH* 7 days ago
I assume you intended to say Q2 and Q3. There will be minimal revenue in Q1 since TIL revenue is only recognized upon infusion which would occur at around day 34 post surgery which puts the first patient into Q2. There will probably be some revenue as ATCs stock IL-2 in preparation, but think that will be minimal... maybe $4-5M.

Your Q2 numbers are aligned with what I have at about 90-120 patient starts. Your Q3 numbers implies a total billings of 360-480 patients. That does seem high to me but would be 2.4-3.2 patients per ATC per month, so not impossible. IOVA indicated an annual total spend of $320M-$340M (which would include manufacturing costs) or $80M-85M per quarter, your numbers would make IOVA extremely profitable at Q3. I hope your numbers are correct, but just wanted to temper expectations a bit.

As an aside, the 12 analysts tracking IOVA do have them as break-even by 2026, which I think is very conservative. Break-even is the holy grail for any biotech as it means limited dilution risk. Break-even should occur at about 160-170 patients per quarter or a little over 1 patient start per ATC (assuming 50 ATCs) per month.
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badgerkid badgerkid 1 week ago
Welcome to the board, neptunesashimi.
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badgerkid badgerkid 1 week ago
Inducement grants awarded. Here's the cool part:

"... today announced that on April 18, 2024 (the โ€œDate of Grantโ€), the Company approved the grant of inducement stock options covering an aggregate of 79,310 shares of Iovanceโ€™s common stock to thirty-seven new, non-executive employees..."

That's 37 new employees. Just saying.

https://ir.iovance.com/news-releases/news-release-details/iovance-biotherapeutics-reports-inducement-grants-under-17
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neptunesashimi neptunesashimi 1 week ago
Firmly believe in IOVA's fundamentals
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neptunesashimi neptunesashimi 1 week ago
Nice DD, GMH
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neptunesashimi neptunesashimi 1 week ago
Nice ddm GMH.
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MN Gopher MN Gopher 1 week ago
GMH, good analysis. To me it should land Q1 between 45 & 60 million.
Q2 between 180 mil & 240 million

Lets see how it plays out in 2024 to have a good idea where 2025 takes us.
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badgerkid badgerkid 1 week ago
GMH, thank you for sharing. I concur.
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GMH* GMH* 1 week ago
I do not think the company will give any guidance until the Corporate Update for 2025 (next Feb). I think they will only report out actual starts (thru end-April for Q1, end-July for Q2, etc) which does give some clarity for next quarters' revenue.

In regards to my estimate, since there is no new data, I have revised my starts to about 115 thru April 30. This is based on the following assumptions:
1) Linear ramp based on starts thru Feb (approximately 1.55 patient starts per ATC per month) for the 30 existing ATCs (assuming no adds from the 6 additional ATCs thru April)
2) Fred's comments upon approval and re-iteration during Cowen fireside that the 20 patients were "a tiny fraction of the bolus".
3) Build of of the iCTC for a capacity of 2,000 (165/month) plus a vendor back up because they did not want to end up in a situation similar to the CAR-T roll out where initial demand outstripped capacity.
4) ATCs investment in time and resources (200 hours for the lead physician + support staff training plus infrastructure) is a big commitment from the Cancer Centers so they would expect some demand before committing to becoming an ATC.

The Q2 analyst revenue projections are 5.2M (low), $28.6M (average) and $60.6M (high). This equates to about 10, 58 and 122 starts thru April. We are already way over the 10 thru Feb and only an additional 38 to get to the average. I am confident that we will blow away those 2 and should be closer to the top-end. I was playing that expected pop using some options, but this continued weakness may not hit those strikes even with a substantial beat.

This weakness continues to surprise me. I will probably add some additional lower strike options right before earnings if this weakness/lower level continues.
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badgerkid badgerkid 1 week ago
Surfkast, we're all down from the high. I wish you good luck and a nice run up soon, but this is still all about earnings going forward and the time it'll take to book those earnings IMO. The entire sector has not been our friend ever since we hit the high as did the sector funds. It's all down.
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badgerkid badgerkid 1 week ago
GMH, have you got any updates on your expectations for guidance regarding Q2, 3 and 4?

I think we're at 36 ATC's currently with the goal of 50 by end of May or June? Somewhere around there.

Thanks in advance.
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surfkast surfkast 1 week ago
Been retired and still up but down from the high big time here.
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GMH* GMH* 1 week ago
Right now I am pretty much all-in on the market (as I was during all of my working career). In retirement, I set up 3 years worth of expenses in a CD ladder (and can extend to 4 if I use my dividends). This will allow me to ride out most of the normal downturns. Political events are always short lived... remember Russia/Ukraine was only a 3 month market downturn and that probably has more ramifications that the Middle East.

Over the long term, a stocks fundamentals will come thru. It is just important to know why you own the stock and when that thesis no longer holds (i.e. price target met or facts change). Stock price at any given time is impacted by a lot of factors but over time, it is the stock fundamentals that matter. Buffet's voting machine vs weighing machine quote.
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badgerkid badgerkid 1 week ago
Surfkast, all markets are affected by uncertainty. People move to safety when things look scary, rational thought is affected by fear. The media will hype even the smallest of negative events, but imagine if the Middle East escalates. Oil goes up, many stock prices come down, fundamentals take a back seat for awhile.

Sunman knows that rebounds for the good companies will happen as certainty returns, but keeping dry powder allows us to pick up a few good companies on the cheap (or cheaper at least) during those times of uncertainty.

If you're of retirement age, there's nothing worse than a negative market sentiment when you want to sell down your positions. If you're younger, these are the times to build portfolios using sound fundamentals.

Good luck. Sunman knows of what he speaks, or so it has always seemed to me.
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surfkast surfkast 1 week ago
I don't see how a cancer cure is affected by something over there.
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Sunman88 Sunman88 1 week ago
A bumpy ride ahead is more likely now for the next several months.
Save dry powder. It will come in very handy.
Sounds cryptic, but tje axis of evil is using the playbook to incite the Middle East and prolong uncertainty and anxiety.
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surfkast surfkast 1 week ago
I held and missed a very nice score. Still up and waiting.
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badgerkid badgerkid 1 week ago
Gopher shared a short article with me and asked that I share it here (some guy named Warren Buffett). I think the message is timely for some of us (definitely me) who get frustrated that the stock price isn't always in line with our fundamental thinking about any particular company that we find ourselves invested in. Thanks Gopher.

https://www.msn.com/en-us/money/savingandinvesting/warren-buffett-criticizes-stock-market-forecasters-make-fortune-tellers-look-good-labels-them-poison-to-be-kept-locked-up/ar-BB1lHZsX?ocid=msedgntp&pc=SMTS&cvid=a5158db669ed48ec80ca132d1902730c&ei=97

It might be a little sales pitchy, but there's some meat in there as well.

Good luck to the longs.
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GMH* GMH* 1 week ago
I would suggest not measuring yourself against perfection (buying at the low and selling at the high). It will drive you crazy. The only points that matter is when you buy and when you sell... ignore the lower lows and higher highs in between. If you made a good return from when you bought to when you sold, it was a good trade/investment.
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