RNS Number:5847S
Alexon Group PLC
27 November 2003


                           SCHEDULE 10
 
             NOTIFICATION OF MAJOR INTERESTS IN SHARES


1)   NAME OF COMPANY

     ALEXON GROUP PLC


2)   NAME OF SHAREHOLDER HAVING A MAJOR INTEREST

     CAPITAL GROUP


3)   Please state whether notification indicates that it is in respect of 
     holding of the Shareholder named in 2 above or in respect of a 
     non-beneficial interest or in the case of an individual holder if it is a
     holding of that person's spouse or children under the age of 18

     


4)   Name of the registered holder(s) and, if more than one holder, the 
     number of shares held by each of them.

     SEE LETTER BELOW


5)   Number of shares/amount of stock acquired.

     

6)   Percentage of issued Class



7)   Number of shares/amount of stock disposed



8)   Percentage of issued Class



9)   Class of security

     ORD 10P SHARES



10)  Date of transaction




11)  Date company informed

     27/11/03


12)  Total holding following this notification

     3,065,281

               
13)  Total percentage holding of issued class following this notification

     4.953%


14)  Any additional information




15)  Name of contact and telephone number for queries

     R PIGGOTT
     01582 723131


16)  Name and signature of authorised company official responsible for 
     making this notification


     Date of Notification     27 NOVEMBER 2003



To: Alexon Group plc
Dated: 24 November 2003

Re:  Section 198 Notification

Corporate Secretary:

Enclosed is a Section 198 Notification dated 21 November 2003. This disposition
of shares was not a market transaction, but a transfer of shares due to the
termination of a client account.

Please note that one or more of the affiliates of The Capital Group Companies,
Inc. have made notifications to your company pursuant to Section 198 previously.
For a description of our organization, please visit our Web site at
www.capgroup.com.

For the purposes of this Notification an outstanding share balance of 61,893,001
shares was used to calculate the percentages of holdings of the relevant share
capital which determine the notifiable interest. We believe this outstanding
share balance is current; however, if this number is not accurate, please
contact us as soon as possible so we may make the necessary revisions to this
Notification.

From: Capital Group Companies



LETTER TO:  ALEXON GROUP PLC  
DATED 21 NOVEMBER 2003

                          SECTION 198 NOTIFICATION 
                          Notification of Decrease

This Notice is given by The Capital Group Companies. Inc. on behalf of its
affiliates, including Capital International SA, Capital International Limited,
Capital International, Inc., and Capital Guardian Trust Company, pursuant to
Section 198 of the Companies Act 1985.

The interest in the relevant share capital indicated below arises by virtue of
holdings attributed to the Companies (see Schedule A). These holdings form part
of funds managed on behalf of investment clients by the Companies.

Share capital to which this relates:

Ordinary Shares (61,893,001 shares outstanding) 

Number of shares in which the Companies have an interest;

3,065,281 

Name(s) of registered holder(s);

See Schedule B



As of 21 November 2003 

Alexon Group plc
 
                                               Number of Shares       Percent of
                                                                     Outstanding

The Capital Group Companies. Inc. ("CG") holdings   3,065,281          4.953%

Holdings by CG Management Companies and Funds:

-   Capital Guardian Trust Company                  2,148,904          3.472%

-   Capital International Limited                     781,529          1.263%

-   Capital International S.A.                         40,191          0.065%

-   Capital International, Inc.                        94,657          0.153%


                                    Schedule A



                    Schedule of holdings in Alexon Group plc 
                               As of 21 November 2003

                           Capital Guardian Trust Company
 

Registered Name                                                     Local Shares 

State Street Nominees Limited                                              9,452

Chase Nominees Limited                                                 1,928,989

Midland Bank plc                                                         210,463

                                              TOTAL                    2,148,904


                                  Schedule B

                         Capital International Limited

Registered Name                                                     Local Shares

Chase Nominees Limited                                                   781,529

                                              TOTAL                      781,529



                          Capital International S.A.
 
Registered Name                                                     Local Shares

Citibank London                                                           40,191

                                              TOTAL                       40,191



                           Capital International Inc.
 
Registered Name                                                     Local Shares 

State Street Nominees                                                     29,809

Chase Nominees Limited                                                    64,848

                                              TOTAL                       94,657





                      This information is provided by RNS
            The company news service from the London Stock Exchange

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