By Barbara Kollmeyer, MarketWatch

MADRID (MarketWatch) -- Stocks in Spain sank 3% on Friday as a global selloff continued a second day, intensifying for Europe as fears over China and emerging markets smacked sentiment.

Banks and drug stocks were the biggest losers, though shares of Celesio AG were up on buyout news.

Decliners swamped gainers on the Stoxx Europe 600 index , which tumbled 1.4% to 327.86. The index closed 1% lower to 332.69 on Thursday for the biggest one-day percentage loss since early December, while in the U.S., the Dow industrials (DJI) suffered the worst loss in five weeks.

Shares of Celesio AG jumped more than 5%, the biggest gainer on the main European index. On Thursday, U.S. drug distribution group McKesson Corp. (MCK) said it had agreement from German conglomerate Franz Haniel & Cie, a major shareholder in Celesio, to sell its 50% stake in the company for 23.50 euros a share. McKesson also persuaded Elliot Management to release convertible bonds in the company.

Nokia (NOK) rose 1.3% after analysts at Societe Generale lifted shares to buy from hold, citing a buying opportunity after Thursday's 11% share-price fall. Nokia shares fell on disappointing results, but analysts at SocGen said there was some hope in upwardly revised guidance for intellectual-property license fees from EUR500 million to EUR600 million annually, due to higher fees expected from Microsoft Corp. (MSFT).

Sentiment was worsening as the morning progressed, matched by a sharp decline for U.S. stock futures. Asia stocks posted sharp losses overnight, with the Hong Kong Hang Seng index dropping 1.2% and the Nikkei 225 index losing close to 2%.

"There's a number of reasons why investors are feeling a little down in the dumps at the moment," said Craig Erlam, market analyst with Alpari U.K., in a note. "Corporate-earnings season has been mixed from an investor standpoint, and disappointing from an economic one. Companies have continued to focus on the bottom-line growth driven by cost-cutting rather than investment and stronger revenues, which is what we'll need to see if the recovery is going to gather pace this year."

The biggest losses were seen in Spain, where the IBEX 35 index tumbled 2.7% to 9,961.10 with Banco Santander SA (SAN) sinking 2.4% and BBVA SA (BBVA) tanking 5% amid a currency crisis in Argentina in which the central bank reportedly gave up its fight to support the peso. Spain has deep ties to Latin America, and its banks are particularly active there.

The banking sector fell sharply across Europe, with HSBC Holdings PLC (HSBC) down 1.5% and Credit Suisse Group AG slid 3%.

Within other indexes, the German DAX 30 fell 1.3% to 9,508.04, while the FTSE 100 index lost 1% to 6,706.31.

Among other stocks, shares of Sanofi SA (SNY) slid 3% after the pharmaceutical group was cut to neutral from buy at Citigroup, where analysts said consensus downgrades are likely, given recent pipeline/divisional disappointments. Losses for the heavyweight weighed on the French CAC 40 index , down 1.3% to 4,221.12.

Also in the drug space, shares of Novartis AG (NVS) dropped 1.6%. The company said it would request re-examination of its serelaxin treatment in acute heart failure for conditional marketing-authorization in the EU, following a negative opinion from the European Medicines Agency's Committee for Medical Products for Human Use.

From Davos and the World Economic Forum on Thursday, Bank of England Gov. Mark Carney signalled in a television interview that interest rates won't need to rise immediately despite the unemployment rate falling to within 0.1 percentage point of the 7% threshold he previously said would trigger consideration of a hike.

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