By Tom Fairless 

LONDON--Europe's top competition official launched a robust defense of her agency's independence on Thursday, denying suggestions she has pursued political goals in targeting major overseas companies including Apple Inc. and Google Inc.

Margrethe Vestager, who took over as the EU's antitrust chief in November, rocked the business world in April by filing f ormal charges against Google and Russian energy giant OAO Gazprom in the same week for allegedly abusing their market power.

Both were highly sensitive moves against two of the world's biggest and best-connected companies, from which her predecessor, Joaquín Almunia, had held back for years.

Ms. Vestager's agency has also repeatedly deepened an investigation into the tax practices of multinationals that has embroiled major companies including Amazon.com Inc. and Starbucks Corp.

Speaking on Thursday at Chatham House in London, Ms. Vestager conceded that the decision to focus on specific sectors, such as energy and information technology, was driven by political goals. But she insisted she had approached individual cases fairly and in strict accordance with the law.

"Some commentators have been quick to make political inferences," Ms. Vestager said.

But "independence is simply nonnegotiable," she said.

The European Commission, the bloc's executive arm and top antitrust authority, acts as prosecutor, judge and jury in EU competition cases, giving it greater powers than U.S. antitrust agencies, which must defend their cases before a judge.

Ms. Vestager said the current commission has consciously prioritized antitrust cases where it believes its actions "would have a multiplier effect with (its) wider political priorities."

The Commission, led by former Luxembourg Premier Jean-Claude Juncker, has announced a number of key objectives for its current five-year term, including deepening the bloc's single market for digital services and energy, and ensuring all companies pay their fair share of tax.

"There should be no doubt that I will do my part to advise the commission's broader objectives," Ms. Vestager said.

But to the question of whether EU competition policy is politicized in individual cases, Ms. Vestager said the answer is "a resounding no."

She stressed that her agency has to defend its decisions against legal challenges in the EU courts in Luxembourg.

"We are committed to the principles of fairness, good administration, transparency and good process," she said.

"There is simply no room to spare...for political interference."

The commissioner also warned against new EU regulations that could target large Internet companies like Google and Facebook Inc., arguing that the bloc should seek first to enforce its existing laws to keep big companies in check.

Senior EU officials in February floated a plan to create a new EU-wide regulator for a swath of mainly US-based Internet companies, amid concerns that some of these firms are obstructing access to key online markets, according to an internal document seen by The Wall Street Journal.

The EU has since said it would investigate how such companies operate in Europe before deciding on any next steps, though the bloc's German-born digital commissioner Günther Oettinger has indicated that regulation is still on the table.

But Ms. Vestager said it would be "tricky" to design an EU regulation targeting disparate Internet firms such as Facebook, Amazon.com Inc. and eBay because it was hard to establish what they had in common besides "facilitating something."

She stressed that her agency already has strong tools to tackle abuses by large Internet companies. Besides filing formal antitrust charges against Google in April over its search practices in Europe, the EU has also opened an investigation into possible barriers that some online companies may have created to cross-border electronic commerce in Europe.

New regulations aimed at large Internet companies would take years to create and would necessarily address past rather than future problems, Ms. Vestager said.

"We need to think about what it is we want to achieve that can't be achieved by enforcing competition law," she said.

Much of the behavior by Internet firms, she added, was "very ordinary," and didn't require new tools to address.

"They want to make more money than their competitors, some want a competitor not to be there," Ms. Vestager said.

Write to Tom Fairless at tom.fairless@wsj.com

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