By Tom Fairless 

BRUSSELS-- Amazon.com Inc.'s tax arrangements in Luxembourg may violate European Union law and give the U.S. company an illegal advantage over competitors, EU regulators said Friday, in a preliminary decision that lays out the rationale for launching a detailed investigation three months ago.

The probe is part of a broader crackdown on tax avoidance by multinationals in Europe, where governments are scrambling to shore up their revenues and assure citizens that everyone is contributing fairly to crisis-hit budgets. Amazon could be required to pay back large sums in back taxes if the regulator's suspicions are confirmed.

The European Commission, the EU's top antitrust authority, said the method used to calculate taxes under a 2003 deal granted to Amazon in Luxembourg didn't appear to comply with international guidelines.

An internal royalty fee, paid from one Luxembourg subsidiary of Amazon to another for the use of intellectual property, "is not related to output, sales, or to profit," the regulator said. The royalty fee has the effect of reducing Amazon's tax liabilities in Luxembourg.

The commission said it doubted whether Luxembourg's tax authorities had properly assessed Amazon's tax deal given it was approved within "a very short period of time." It also expressed concern that the deal was still in force after more than a decade "without any revision."

The regulator asked Luxembourg to explain the nature of the intellectual property for which internal fees are paid, and to detail the scale of royalties over the past 10 years.

Amazon and other interested parties have several weeks to provide feedback before the commission announces its final decision.

Write to Tom Fairless at tom.fairless@wsj.com

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