ADVFN Logo ADVFN

We could not find any results for:
Make sure your spelling is correct or try broadening your search.

Trending Now

Toplists

It looks like you aren't logged in.
Click the button below to log in and view your recent history.

Hot Features

Registration Strip Icon for default Register for Free to get streaming real-time quotes, interactive charts, live options flow, and more.
Cyclacel Pharmaceuticals Inc

Cyclacel Pharmaceuticals Inc (CYCC)

1.51
-0.09
(-5.63%)
Closed April 26 4:00PM
1.30
-0.21
( -13.91% )
Pre Market: 4:55AM

Calls

StrikeBid PriceAsk PriceLast PriceMidpointChangeChange %VolumeOPEN INTLast Trade
2.500.200.200.200.200.000.00 %066-
2.500.000.000.000.000.000.00 %00-
5.000.000.000.000.000.000.00 %00-
5.000.000.000.000.000.000.00 %00-
7.500.000.000.000.000.000.00 %00-

Puts

StrikeBid PriceAsk PriceLast PriceMidpointChangeChange %VolumeOPEN INTLast Trade
2.501.553.200.002.3750.000.00 %00-
2.500.000.000.000.000.000.00 %00-
5.000.000.000.000.000.000.00 %00-
5.000.000.000.000.000.000.00 %00-
7.500.000.000.000.000.000.00 %00-

Market Movers

View all
  • Most Active
  • % Gainers
  • % Losers
SymbolPriceVol.
INHDInno Holdings Inc
$ 0.91
(44.33%)
2.43M
YYAIConnexa Sports Technologies Inc
$ 0.9299
(28.94%)
570
CTCXCarmell Corporation
$ 2.55
(22.01%)
238
TIVCTivic Health Systems Inc
$ 1.25
(20.19%)
4
INDPIndaptus Therapeutics Inc
$ 2.50
(18.48%)
48
CLVRClever Leaves Holdings Inc
$ 1.65
(-59.85%)
45.79k
ADXNAddex Therapeutics Ltd
$ 8.01
(-50.25%)
3.51k
ISUNiSun Inc
$ 0.135
(-19.64%)
100.7k
NUZENuZee Inc
$ 1.37
(-15.95%)
2.88k
TSLZT Rex 2X Inverse Tesla Daily Target ETF
$ 33.72
(-14.13%)
92.92k
AKANAkanda Corporation
$ 0.1174
(13.98%)
3.01M
PEGYPineapple Energy Inc
$ 0.071
(13.42%)
2.93M
INHDInno Holdings Inc
$ 0.9122
(44.68%)
2.43M
TSLLDirexion Daily TSLA Bull 2X Trust ETF
$ 8.18
(14.41%)
1.4M
TSLATesla Inc
$ 180.35
(7.17%)
1.32M

CYCC Discussion

View Posts
Awl416 Awl416 4 days ago
What I miss?
๐Ÿ‘๏ธ0
Monksdream Monksdream 1 month ago
CYCC 10Q due 3/19
๐Ÿ‘๏ธ0
chsmoke chsmoke 3 months ago
while s. robotis has certainly got to be in the running for longest serving, worst performing CEO of any American company
in history, one has to admire that decade after decade he is able to draw a sizeable paycheck, while keeping his
handpicked and doubtlessly corrupt bod in his back pocket. he could teach a valuable course at any business school.
what a great subject for a great novel cycc and it's unapologetic, feckless leader would make.
go Spiro go--and you know he will do just that!
๐Ÿ‘๏ธ0
Monksdream Monksdream 4 months ago
CYCC new 52 week low
๐Ÿ‘๏ธ0
chsmoke chsmoke 5 months ago
how has Spiro kept his job?
is there a functioning board of directors?
he's been drawing a big salary without a single thing for an investor to feel good about for so many years. ??????
๐Ÿ‘๏ธ0
glenn1919 glenn1919 6 months ago
CYCC.......................................https://stockcharts.com/h-sc/ui?s=CYCC&p=W&b=5&g=0&id=p86431144783
๐Ÿ‘๏ธ0
Monksdream Monksdream 8 months ago
CYCC new 52. Week low
๐Ÿ‘๏ธ0
Monksdream Monksdream 8 months ago
CYCC new 52 week low
๐Ÿ‘๏ธ0
Monksdream Monksdream 8 months ago
CYCC new 52 week low
๐Ÿ‘๏ธ0
glenn1919 glenn1919 9 months ago
CYCC............................https://stockcharts.com/h-sc/ui?s=CYCC&p=W&b=5&g=0&id=p86431144783
๐Ÿ‘๏ธ0
Triple nickle Triple nickle 9 months ago
Nice buy
๐Ÿ‘๏ธ0
Cytobeliever Cytobeliever 1 year ago
Sar Pas,

No reply to my last post! The stock is now at 73 cents. Get out while you can. It is not on fire! I can't beleive that you have not responded.

He is a scammer and it will soon be delisted or he will have to do another offering. I lost thousands years ago. It is what Spiro does. He keeps on sucking in new money so that he can live the life of luxury while we all lose our shirts. That is what he does. Everyone needs to run as fast as possible and take their loses. This guy and his board should be shut down. I can't stand to see what you are all going through! Get out Now!
๐Ÿ‘๏ธ0
Cytobeliever Cytobeliever 1 year ago
So what do you have to say now? Spiro has been sucking in people for years. Prepare yourself for another reverse split so that he can keep the money rolling in. I lost thousands years ago. He is a scammer! Run!
๐Ÿ‘๏ธ0
judgeybrown judgeybrown 2 years ago
Ihub is a valueless waste land
๐Ÿ‘๏ธ0
SarPas SarPas 2 years ago
Stock is on fire in PM and nobody to comment ? Closed at $1.31 and was up to $1.99 in PM. Wake up people.
๐Ÿ‘๏ธ0
judgeybrown judgeybrown 2 years ago
That was nice :) moving on.
๐Ÿ‘๏ธ0
judgeybrown judgeybrown 2 years ago
This should be the week. See what the universe delivers on this opp. It does what it wants.
๐Ÿ‘๏ธ0
chsmoke chsmoke 2 years ago
spiro rombotis. not just in the usa, but globally, he would be right at the
very top of highest paid, longest standing, and worst ceos. can't even imagine
how corrupt the board is. if he has family, not even they would've let him
keep his job. he's smart, he's very articulate, hard to imagine a bigger fraudster.
if cycc wasn't what it is, he would've been out 10 years ago. or more...
๐Ÿ‘๏ธ0
judgeybrown judgeybrown 2 years ago
Nobody needs to be in here now. But yaโ€™ll will be checking in here later cause we gonna blow this up
๐Ÿ‘๏ธ0
Awl416 Awl416 2 years ago
Movement PM
๐Ÿ‘๏ธ0
alvaroc2 alvaroc2 2 years ago
Enter ar 3,80, bullish by TA, regards
๐Ÿ‘๏ธ0
trickledownfacists trickledownfacists 3 years ago
AH boom
๐Ÿ‘๏ธ0
chsmoke chsmoke 3 years ago
just the fact that spiro and his cohort, i mean cfo, have had
their ludicrous contracts extended is enough to drop the value
of the company almost by 1/5th. the bod of cycc, they must be
some bunch. spiro, he's almost too bad to be true. smart? he is that. deserving to keep his job? oh lord love a duck. even if he
paid himself nothing instead of the ludicrous salary he is paid
he should've been ousted many years ago...
๐Ÿ‘๏ธ0
swingingRichard swingingRichard 3 years ago
We find stuff like CYCC and, unlike the the "mud merchant" we tell you about them BEFORE they pop. This way, you've got a chance to make money and not just be sitting there after the explosion watching a video of some guy drawing arbitrary lines and pontificating about the stock might go up or it might go down.

This chart was looking fantastic June of last year.



๐Ÿ‘๏ธ0
02opida 02opida 3 years ago
Highs are good
๐Ÿ‘๏ธ0
Value_Investor Value_Investor 3 years ago
CYCC hit Another New high $4.45 so far! It is heading onto $4.68 now since the Bottom was $3.12...

๐Ÿ‘๏ธ0
Value_Investor Value_Investor 3 years ago
Another New high $4.34 today! CYCC is heading onto $20 again...

CYCC is much much much cheaper than all its COVID-19 peers now!


๐Ÿ‘๏ธ0
Eaglepointone Eaglepointone 3 years ago
I hope the price stabilizes, 3 - 4$
๐Ÿ‘๏ธ0
Value_Investor Value_Investor 3 years ago
CYCC just hit a New high $4.35 in the Pre-Market session of today! We should see $6 again as soon as tomorrow...

To replicate the Same 7.413-Bagger Strong performance with its NASDAQ-peer (HUSA), CYCC will surge to $23.13 which is 5.74 Times of its current ridiculous low price $4.03!

๐Ÿ‘๏ธ0
02opida 02opida 3 years ago
nice
๐Ÿ‘๏ธ0
Value_Investor Value_Investor 3 years ago
CYCC hit $4.19 today! We should see $6 again as soon as this week...

Super Undervalued now! Hyper Oversold --- from nearly $20 to $3.12!
๐Ÿ‘๏ธ0
02opida 02opida 3 years ago
CYCC ~ looks okay
๐Ÿ‘๏ธ0
Value_Investor Value_Investor 3 years ago
Yes, CYCC bounced to $3.98 today! We should see it soar back to $20 again before the end of 2020 since the company is developing COVID-2019 related hot drugs...

๐Ÿ‘๏ธ0
Value_Investor Value_Investor 3 years ago
CYCC has Very Good News after the market close --- no more share's dilution to raise the cash till 12/31/2022!

CYCC has $4.76 per share Cash Value and $5.03 per share Book Value now!

So it is Extremely Undervalued currently! At Hyper Oversold status now --- from $19.xx to $3.12!

Thus it will Quickly And Easily surge back to its most recent high $19.xx (i.e. nearly $20) again...

CYCC might replicate 7.143-Bagger Quick rally to hit $22.29 like its NASDAQ-peer (HUSA) did!

๐Ÿ‘๏ธ0
02opida 02opida 4 years ago
will move up some
๐Ÿ‘๏ธ0
Value_Investor Value_Investor 4 years ago
Yes, CYCC seems Bottomed out at $3.19! It bounced to $4.25 so far! Easy to surge back to $6.00 again since its most recent high was nearly $20.00...

๐Ÿ‘๏ธ0
02opida 02opida 4 years ago
north is good
๐Ÿ‘๏ธ0
Value_Investor Value_Investor 4 years ago
Can CYCC test its most recent high $6.00 in the next week?
๐Ÿ‘๏ธ0
Value_Investor Value_Investor 4 years ago
CYCC should run in the next week unless any bad news kicks in...
๐Ÿ‘๏ธ0
Value_Investor Value_Investor 4 years ago
Hyper Oversold --- from $20.xx to $3.23?
๐Ÿ‘๏ธ0
Value_Investor Value_Investor 4 years ago
CYCC has bounced to $3.87 so far from the New Bottom $3.23!
๐Ÿ‘๏ธ0
02opida 02opida 4 years ago
will announce second quarter 2020 financial results on Wednesday, August 12, 2020. The Company will host a conference call and live webcast at 4:30 p.m
๐Ÿ‘๏ธ0
dinogreeves dinogreeves 4 years ago
3-4 catalyst awaiting this year for this thing, I would not doubt we will be trading in the teens soon before the end of the year, especially the news regarding their COVID phase in Scotland.
๐Ÿ‘๏ธ0
stock1ace1 stock1ace1 4 years ago
Riding the waves !
๐Ÿ‘๏ธ0
dinogreeves dinogreeves 4 years ago
News very soon.
๐Ÿ‘๏ธ0
dinogreeves dinogreeves 4 years ago
News pending thus the move.
๐Ÿ‘๏ธ0
stock1ace1 stock1ace1 4 years ago
Breakout watch
๐Ÿ‘๏ธ0
dinogreeves dinogreeves 4 years ago
Should get news soon.
๐Ÿ‘๏ธ0
02opida 02opida 4 years ago
Cyclacel โ€™s Clinical Stage CDK2/9 Inhibitor Fadraciclib Targets Key Anti-Apoptotic and Oncogenic Pathways in Cancer

2020-07-13 07:00 ET - News Release

-- Characterization of fadraciclib published in peer-reviewed journal shows specificity against

CDK2 and CDK9 and enablement of apoptosis of cancer cells driven by MCL1, cyclin E and/or MYC โ€“

-- Data builds on growing body of evidence indicating the promise of dual CDK2/9 inhibition --

BERKELEY HEIGHTS, N.J. and DUNDEE, United Kingdom, July 13, 2020 (GLOBE NEWSWIRE) -- Cyclacel Pharmaceuticals, Inc. (Nasdaq: CYCC) (Nasdaq: CYCCP) (Cyclacel or the Company), a biopharmaceutical company developing innovative medicines based on cancer cell biology, today announced publication of a peer-reviewed study of fadraciclib, in PLOS ONE. The publication, authored by scientists from Cyclacel and The Institute of Cancer Research, London, describes the discovery of fadraciclib and shows its ability to target CDK2 and CDK9, leading to broad therapeutic potential.

โ€œThe published findings strengthen the mechanistic rationale for fadraciclibโ€™s potential as an anti-cancer therapy. Building upon previous research in CDK pathways, including the roles of cyclin E, MCL1 and MYC overexpression, the paper highlights the benefits of inhibiting both CDK2 and CDK9, two complementary cancer pathways,โ€ said Spiro Rombotis, President and Chief Executive Officer of Cyclacel. โ€œIndependent findings reported at the ASCO20 Virtual Scientific Program corroborate the attractiveness of this dual targeting approach. Based on recently disclosed clinical data fadraciclib is establishing a leadership position among apoptosis enabling compounds in clinical development. We are encouraged by observations of single agent anticancer activity in our clinical studies. Initial clinical data with oral fadraciclib show concordance with intravenous pharmacokinetics. In parallel with evaluating fadraciclib in patients with acute myeloid leukaemia (AML) and myelodysplastic syndromes (MDS), we are executing a precision medicine strategy to evaluate fadraciclib in patients with solid tumors, with study enrollment expected to begin by Q1 2021.โ€

โ€œThese exciting new findings revealing fadraciclibโ€™s chemical structure and describing its relevant anti-cancer properties, reflect the highly productive collaboration of ICR with Cyclacel to discover and develop innovative cancer treatments,โ€ said Professor Paul Workman, FMedSci, FRS, study co-author and Chief Executive and President, The Institute of Cancer Research, London, UK. โ€œAs a potent and selective inhibitor of CDK2 and CDK9, we believe our cumulative findings to-date support fadraciclibโ€™s ability to address key cancer pathways in solid tumors and leukaemias, indicating its potential as a new targeted anti-cancer therapy.โ€

Cyclin-dependent kinases (CDKs) exist in many isoforms and as key cell cycle regulators can play a critical role in cancer growth. This preclinical characterization of fadraciclib includes its potency and selectivity against CDK2 and CDK9 in vitro and in a broad range of cancer cell lines including AML, breast and colorectal. Further in vivo efficacy was demonstrated in leukemia xenograft models.

Experimental results support fadraciclibโ€™s anti-cancer activity through CDK2/9 inhibition. In breast cancer cell lines, short-pulse treatment with fadraciclib showed preferential activity against transformed cells over normal cells. This finding supports the compoundโ€™s potential benefit in cancers addicted to cyclin E which can be rationally targeted by CDK2 inhibition. In AML models, fadraciclib was effective in inhibiting CDK9 and suppressing the MCL1 protein to induce apoptosis or programmed cell death of leukemia cells. Fadraciclib also demonstrated synergy with BCL2 inhibitors such as venetoclax in AML cells. In subcutaneous mouse xenograft models of AML and MLLr-AML, nearly 100% tumor growth inhibition was achieved with oral administration of fadraciclib at pharmacological doses.
๐Ÿ‘๏ธ0
stock1ace1 stock1ace1 4 years ago
Keep on selling me cheapies
๐Ÿ‘๏ธ0

Your Recent History

Delayed Upgrade Clock