He Believes That Alzheimer's Disease is
Becoming Optional
SANTA
MONICA, Calif., April 16,
2024 /PRNewswire/ -- Pacific Neuroscience
Institute® (PNI) is thrilled to announce that
Dale Bredesen, MD, has joined
Pacific Neuroscience Institute®. Over the past four
months, as the senior director of the nascent Precision Brain
Health program, he and his colleagues have been intensely focused
on developing what promises to be the world's first formalized
system to comprehensively address neurodegenerative disease in the
world. While not quite ready for primetime, the excitement around
the clinical implications for patients is palpable.
"We are entering a new era in medicine," says Dr. Bredesen.
"Younger generations should not have to live with the fear of
Alzheimer's. At PNI, we will be implementing the methodologies that
have arisen from my lab's three decades of fundamental research as
well as our published success. Taking a personalized, biological
systemwide approach and becoming proactive about interventions,
represent the first steps towards stopping Alzheimer's in its
tracks."
Cognitive decline is a complex and chronic process that requires
a multimodal approach, he explains. "We recommend that everyone
begin active prevention when they turn forty, and get a
'cognoscopy', to assess their cognitive health and risk factors.
Our protocol recommends targeted, individualized treatments of
specific chronic infections (which often go undiagnosed) and
identifies cognition-compromising toxins (which are also often
unrecognized). Along with implementing lifestyle adjustments, we
see a lot of hope."
Dr. Bredesen, a trailblazer in cognitive decline research and
author of the first published report of reversal of cognitive
decline, is an internationally recognized neurologist with
expertise in the mechanisms of neurodegenerative diseases. His
years of clinical study and neurological research have opened the
door to new approaches of treatment, leading to the ReCODE
Protocol™. Also known as the Bredesen Protocol, this methodology
has emerged as a viable attempt to prevent, arrest, and reverse
symptoms of cognitive decline associated with conditions such as
Alzheimer's disease, other dementias, and mild cognitive
impairment.
"As a medical community, we have had very little to offer our
patients living with diseases of cognitive decline. Hundreds of
clinical trials have resulted in disappointment," comments
David A. Merrill, MD, PhD, director
of the Brain Health Center at PNI. "Dr. Bredesen's pioneering work
over the last thirty years, along with over two hundred
peer-reviewed publications, and more than thirty patents have
pointed to tremendous promise. Now we are able to 'prescribe'
lifestyle interventions such as exercise and nutrition
recommendations, as well as other precision health interventions,
that together can materially move people onto an alternate life
trajectory – one that could circumvent cognitive decline."
PNI Foundation launched a separate Brain Wellness &
Lifestyle educational program led by Karen
Miller, PhD, and her team of expert brain health coaches in
2022. They are already helping hundreds of clients through
customized courses that incorporate lifestyle recommendations along
with both physical and cognitive training.
Dr. Bredesen is working closely with Dr. Merrill on the clinical
side of brain health and Dr. Miller on the lifestyle intervention
side. "The Precision Brain Health program will integrate both of
these aspects of care along with complete cognitive testing,
genetic analysis, phenomic (biochemical) analysis, long term action
plans, and more," explains Dr. Bredesen. "I'm optimistic that
outcomes will continue to improve—we are seeing that people with
cognitive decline can, and do, get better. Pacific Neuroscience
Institute has a history of innovation that fits perfectly with the
development of this novel program."
More than six million Americans live with Alzheimer's
disease—the most common type of dementia—suffering progressing
symptoms of memory loss, confusion, behavioral change, and the loss
of body control. It is unusual that deep scientific research comes
to mainstream awareness, yet with a cure—or even an effective
treatment—being frustratingly elusive, Dr. Bredesen's 2017 New York
Times bestselling book, The End of Alzheimer's, captured the
public's attention. The End of Alzheimer's Program and
The First Survivors of Alzheimer's, further provide
documentation of individuals who reversed their cognitive decline
using the ReCODE Protocol.
"A multidisciplinary approach to complex problems of the brain
and mind has been foundational to our success at PNI and
specifically at the Pacific Brain Health Center since its inception
in 2018. As we hone the Precision Brain Health program, our
aspirational goal is to provide actionable and realistic options to
improve brain health and overall quality of life," says PNI
director and founder, Daniel F.
Kelly, MD. "So far, results from clinical trials, and
evidence-based lifestyle practices suggest that with Dr. Bredesen's
vision and multipronged approach, we may begin to see substantial
numbers of dementia patients achieve a slowing and, in some cases,
even a sustained reversal of cognitive and memory decline."
Dr. Bredesen earned his medical degree from Duke University Medical Center and served as chief
resident in neurology at the University of
California, San Francisco, before joining Nobel laureate
Stanley Prusiner's laboratory at
UCSF as an NIH postdoctoral fellow. Prior to joining PNI, Dr.
Bredesen held University of California
faculty positions at UC San Francisco, UCLA, and UC San Diego. He directed the Program on
Aging at the Burnham Institute and joined the Buck Institute as
founding president and CEO. Currently, in addition to his role at
PNI, he is chief scientific officer at Apollo Health.
About Pacific Neuroscience Institute
Pacific
Neuroscience Institute® is devoted to the comprehensive
care of patients with a wide spectrum of neurological and cranial
disorders. Dedicated teams of specialists, state-of-the-art
facilities, and the use of leading-edge treatment along with our
collaborative approach ensure that each patient receives the
attention they require for successful treatment and recovery. PNI's
specialty clinics are located at award winning hospitals Providence
Saint John's Health Center in Santa
Monica, Providence Little Company of Mary Medical Center in
Torrance, and Saint Joseph Medical
Center in Burbank, California.
PacificNeuro.org
Media Contact
Zara Jethani
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SOURCE Pacific Neuroscience Institute