Medtronic Inc. shareholders approved the company's $43 billion acquisition of Ireland's Covidien PLC on Tuesday, putting the deal on track to close by the end of January or early February.

About 75% of Medtronic's shareholders voted in favor of the deal, based on preliminary results. Covidien also said Tuesday that its shareholders have approved the deal, leaving approval from Ireland's High Court as the final hurdle to the deal's closing

The merger combines two of the world's largest medical-supply companies. Medtronic, based in Minneapolis, will redomicile in Ireland once the merger is completed, part of a wave of controversial deals aimed at taking advantage of lower corporate-tax rates overseas.

Investors had been concerned that the merger would be one of the casualties of the Treasury's crackdown on inversions last year that led some companies to call off deals. AbbVie Inc., for instance, called off its $54 billion acquisition of Shire PLC in October.

Write to Chelsey Dulaney at Chelsey.Dulaney@wsj.com

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