By David Wighton 

LONDON--The last time an American investment banker headed a British bank, it didn't end well. Bob Diamond was ousted as chief executive of Barclays PLC under pressure from regulators in 2012.

Bill Winters, an American investment banker, was named Thursday to replace Peter Sands as CEO of Standard Chartered PLC. An Anglophile who has lived in London for 23 years, Mr. Winters has a much more cautious image than the swashbuckling Mr. Diamond.

During a 26-year career in J.P. Morgan Chase & Co.'s investment bank, Mr. Winters developed a reputation as a savvy markets practitioner and a conservative risk manager. Obsessed about the bank's vulnerability to bad loans, he would boast about how little the bank lent, rather than how much.

During the Russian debt crisis in the late 1990s, this approach helped limit J.P. Morgan's losses. And his stewardship of the investment bank was viewed as one of the reasons that J.P. Morgan Chase weathered the financial crisis better than many of its rivals. He played a central role in the acquisition and integration of ailing investment bank Bear Stearns in early 2008.

Mr. Winters, who is now 53, came to be regarded as a strong contender to eventually succeed James Dimon as the overall bank's CEO. But Mr. Winters was abruptly ousted in 2009. He told friends that one reason Mr. Dimon sacked him was that Mr. Winters did not believe in the universal-banking model, where institutions combined large investment banking operations with big retail banks.

Former colleagues say Mr. Winters can at times be blunt and hot-tempered. But he also has a lighter side. In a promotional video last year for London's Young Vic theater, of which Mr. Winters is on the board, the banker participated in a skit that featured him and other financiers ripping open their shirts and belting out a show tune.

After leaving J.P. Morgan, Mr. Winters was considered for a number of bank CEO jobs, including roles at UBS AG, Barclays and Royal Bank of Scotland Group PLC, according to people familiar with the matter. Instead he set up an asset-management business, Renshaw Bay, to buy assets that were expected to be sold by downsizing banks. But the opportunities were scarcer than expected, prompting renewed speculation that Mr. Winters might be tempted to take a big bank job.

His reputation was enhanced by his role as a member of the U.K.'s Independent Commission on Banking that, in 2011, advised the government to force British banks to ring-fence their retail operations from their investment banking businesses.

Mr. Winters is a surprising choice for the Standard Chartered job because he has no direct experience of Asia, where most of the bank's operations are based, or of retail and commercial banking.

One large Standard Chartered shareholder said that there was "no superman" in the world who ticked every single box for the job. But Mr. Winters had an excellent reputation for building good teams and would likely bring in executives "to cater to the areas where he has a perceived weakness", the investor said.

Write to David Wighton at david.wighton@wsj.com

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