By Dan Strumpf And Saumya Vaishampayan 

U.S. stocks opened lower, giving back ground after major indexes posted their biggest weekly gains in more than a year.

The Dow Jones Industrial Average slipped 71 points, or 0.4%, to 16734. The S&P 500 index declined 12 points, or 0.6%, to 1953. The Nasdaq Composite Index fell 26 points, or 0.6%, to 4457.

The decline comes on the heels of a volatile few weeks for stocks. Last week, strong earnings reports from companies like Microsoft helped boost the S&P 500 4.1% for the week, marking its largest weekly percentage gain since January 2013. The Nasdaq Composite increased 5.3%, the biggest weekly percentage gain since December 2011.

Energy shares were the biggest decliners as crude-oil prices tumbled. The S&P 500 energy index fell 2.9%. Shares of Chevron Corp. tumbled 1.9%. Exxon Mobil fell 1.7%.

While global growth concerns have sent stocks gyrating in recent weeks, investors have recently shifted their attention to the third-quarter corporate earnings season and signs of U.S. economic improvement. As of Friday, when 208 companies of the S&P 500 had reported results, the index was on track for 5.6% earnings growth from a year earlier, according to FactSet.

That is higher than the 4.5% earnings growth expected before the reporting season began. Continued earnings growth and positive economic data should lift stocks, said Jonathan Golub, chief U.S. market strategist at RBC Capital Markets.

Domestically oriented companies in the S&P 500 are doing better than those that are internationally focused, he said. "It highlights the fact that the U.S. economy is in pretty good shape," he said.

Meanwhile, European markets skidded despite news that the European Central Bank's stress tests showed that all but 13 of the region's leading banks have enough capital to survive another period of economic turbulence. The stress tests are part of an effort to reassure investors that European lenders are back on track.

Italian banks were a weak spot. Four Italian banks were told they need to raise more capital, weighing on that country's stocks. The Stoxx Europe 600 fell 0.9%.

The decline comes amid persistent skepticism among investors about the health of Europe's banks and the ability of the ECB to cope with a broader economic slowdown, said Michael O'Rourke, chief market strategist at JonesTrading.

"You could say every bank in Europe is healthy and I'm pretty sure 99 out of 100 investors would doubt that," he said.

Meanwhile, Brazil's elections concluded Sunday, with President Dilma Rousseff winning a second term by a narrow margin. Brazil's Bovespa fell 4.9% Monday.

In commodity markets, crude-oil futures fell sharply, and were recently down 1.5% at $79.75 a barrel. Gold futures inched down 0.1% to $1230.80 an ounce.

And in the U.S., pending sales of existing homes increased 0.3% to a seasonally adjusted index level of 105 in September from August, the National Association of Realtors said Monday. An index level of 100 is considered an average level of contract activity. The increase was smaller than expected.

A gauge of Texas-area manufacturers is scheduled for release at 10:30 a.m. EDT.

Later in the week, the Federal Reserve is due to hold a two-day policy meeting starting Tuesday. On Thursday, investors will get an update on third-quarter U.S. economic growth, expected to show growth of 3.1%.

"This is a pivotal week overall," Mr. O'Rourke said. "The amount of news we have coming out should fuel volatility in both directions."

The yield on the 10-year Treasury note fell to 2.257%. Yields fall as prices rise.

In earnings news, Merck Co. reported earnings that beat analysts' expectations, but revenue fell short. The pharmaceutical giant tightened its earnings outlook for the year by three cents on each end, now expecting $3.46 to $3.50 a share. It also cut the top end of its revenue forecast and now expects $42.4 billion to $42.8 billion for the year. Shares fell 0.9%.

Valeant Pharmaceuticals International Inc. said it is prepared to raise its offer for Allergan Inc. to at least $200 a share. Allergan also reported third-quarter earnings that beat expectations and raised its guidance for the year. Shares of Allergan eased 0.2%.

Write to Dan Strumpf at daniel.strumpf@wsj.com and Saumya Vaishampayan at saumya.vaishampayan@wsj.com

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