RNS Number:9996H
Alizyme PLC
26 February 2003

For Immediate Release                                           26 February 2003

                                  ALIZYME PLC

                            DIRECTOR SHARE PURCHASE

Alizyme plc (the "Company") received notification yesterday that the following
Director purchased 67,658 ordinary shares of 2p each in the capital of the
Company ("Shares"). These Shares were purchased as part of the Placing and Open
Offer and are in addition to the 53,571 Shares announced on 20 February 2003.


Director                  No. of           Date                    Price     Subsequent       Percentage of
                          Shares           purchased               per       total            issued share
                          purchased                                Share     beneficial       capital following
                                                                             holding          purchase

William Edge              67,658 (i)       20 February 2003        #0.28     575,102          0.42%


(i) All 67,658 Shares registered in the name of Rowan Nominees Limited.


For further information, please contact:

Mr Tim McCarthy, Finance Director
Alizyme Plc                                          Tel No: + 44 (0)1223 896000

Lisa Baderoon
Buchanan Communications                            Tel No: + 44 (0) 20 7466 5000


Further information on Alizyme can be found on the Company's website:
www.alizyme.com


                      This information is provided by RNS
            The company news service from the London Stock Exchange
END

RDSNKAKNDBKDOBB