Company Also Spotlights How its Glycan Analysis
Kit Has Saved Biopharmaceutical Industry Nearly Four Years of Lab
Work
Waters Corporation (NYSE:WAT) today unveiled its new line of
differential scanning calorimeters reaffirming TA Instruments'
position as the technology and global leader in thermal analysis at
the 2016 Pittsburgh Conference on Analytical Chemistry and Applied
Spectroscopy. Additionally, the company highlighted new CORTECS®
column chemistries and reported that its GlycoWorks™ RapiFluor-MS™
N-Glycan Kit has already saved biopharmaceutical laboratories
industry-wide approximately four years of work based on sales in
just its first year of availability.
"Innovation is the engine that drives Waters," said Christopher
J. O'Connell, President and CEO of Waters Corporation. "From the
days of Jim Waters, our commitment to innovation has been deeply
engrained in the organization's make-up. For decades, the
organization's central focus has been to innovate and push the
boundaries of analytical science to develop and support the
technologies that enable our customers around the globe to be
successful. Seeing the comprehensive product portfolio from Waters
and TA Instruments here at Pittcon underscores the company's
innovation leadership."
Three new Discovery DSC systems
The new line of Differential Scanning Calorimeters, the
Discovery DSC 2500, DSC 250, and DSC 25 feature enhanced sensing
technologies resulting in unprecedented performance in baseline
flatness, sensitivity, resolution, and reproducibility.
At the core of every new Discovery DSC is the exclusive TA
Fusion Cell™, which incorporates design concepts that “fuse”
together features of the Q-Series and first generation Discovery
DSC, patented Tzero® technology, and new proprietary manufacturing
processes. Additionally, an app-style user interface is standard
with each new model and combined with powerful new TRIOS software,
automated calibration and verification routines work seamlessly to
dramatically improve laboratory work-flows and productivity.
The Discovery DSC measures the change in energy in a sample as
the temperature is raised or lowered. It is used for a wide range
of applications, including material science, pharmaceuticals,
chemistry and studies of biomaterials. It excels in both research
environments and production control processes.
"DSC is the anchor of a thermal analysis laboratory," said Terry
Kelly, President of TA Instruments. "In terms of performance and
ease-of-use the new Discovery Series DSC is so advanced, that
upgrading to one of our powerful new systems will bring scientists
lasting benefits."
The DSC 2500 comes standard with all options, which includes the
all-new linear autosampler that allows for enhanced flexibility in
assigning sample and reference pans to any combination of the
available 54 positions. We believe that it is the only DSC on the
market capable of making and storing heat capacity measurements in
a single run.
The DSC 250 is a flexible and configurable research-grade DSC
that includes Tzero technology, and is well-equipped to satisfy the
most demanding researcher. The DSC 25 is a cost-effective, easy to
use, general purpose DSC with performance superior to competitive
research grade systems. It is ideal for research, teaching, and
quality control laboratories that require a rugged, reliable, basic
DSC.
GlycoWorks Saves Industry Nearly Four Years of Work
Emphasizing the impact of its innovations, Waters revealed that
its GlycoWorks RapiFluor-MS N-Glycan Kit has already saved
biopharmaceutical laboratories industry wide approximately four
years of work in just its first year of availability. These
calculations are based on purchases by all 15 top revenue
generating pharmaceutical companies and 90% of the top
biopharmaceutical companies with glycoproteins in their
pipeline.
Most biotherapeutic proteins available on the market today are
glycoproteins. The heterogeneous glycan populations on these
proteins are critical quality attributes that affect potency,
stability, and therapeutic safety profiles. As a result,
biopharmaceutical companies must provide detailed structural
information pertaining to the glycans attached to their
biotherapeutics when submitting new applications to regulatory
authorities and on an ongoing basis throughout the manufacturing
process. Waters estimates about 4.4 million released glycan
analyses are performed per year, and that number is growing at
double digit rates.
A ground-breaking technology for characterizing glycoproteins,
the GlycoWorks RapiFluor-MS N-Glycan Kit combined with Waters'
ACQUITY UPLC® System, the ACQUITY UPLC® FLR Detector and the
ACQUITY® QDa® Detector, and enables scientists to analyze released
N-glycans and achieve new levels of speed, sensitivity, simplicity
while obtaining previously unattainable structural information.
Expansion of CORTECS Solid-Core LC Columns
Waters today added to its CORTECS® Columns product family with
the introduction of two new LC column chemistries. Built on Waters
proven solid-core particle technology, the Waters® CORTECS® C8 and
CORTECS® Phenyl analytical columns are designed for scientists who
need to expand their chromatographic separation space while
maximizing the speed, resolution and sensitivity of their small
molecule HPLC, UHPLC or UPLC® separations. Capable of operating at
very high column efficiencies and low backpressures, the new
columns give scientists additional selectivity choices and allow
them to develop methods quickly, and generate more information with
every analytical run. The CORTECS C8 and CORTECS Phenyl chemistries
are available in two particle sizes, 1.6 and 2.7 micron, and are
offered in a total of 50 unique column configurations.
CORTECS C8 Columns exhibit a lower hydrophobicity when compared
to typical bonded C18 phases and are useful for separating strongly
hydrophobic compounds. They are also ideal for chemists looking to
transfer or scale compendial C8 HPLC methods to a more robust
column technology.
CORTECS Phenyl Columns are an excellent alternative to typically
bonded C18 phases, particularly for aromatic compounds, based on
the unique selectivity provided by the Phenyl bonded phase.
For More on Waters at Pittcon
Also being shown for the first time at Pittcon are the Waters®
ACQUITY Arc™ System, VionTM IMS QTofTM Mass Spectrometer, and HDI®
Software. For a comprehensive view of Waters' activities at Pittcon
2016, including a full list of products, in-booth activities and
technical presentations, please visit www.waters.com/pittcon.
About Waters Corporation (www.waters.com)
Waters Corporation (NYSE:WAT) develops and manufactures advanced
analytical and material science technologies for laboratory
dependent organizations. For more than 50 years, the company has
pioneered a connected portfolio of separations science, laboratory
information management, mass spectrometry and thermal analysis
systems.
Waters, GlycoWorks, RapiFluor-MS, ACQUITY, ACQUITY Arc, ACQUITY
UPLC, UPLC, Vion, CORTECS, Fusion Cell, Discovery DSC, Tzero, QDa,
HDI, and The Science of What’s Possible are trademarks of Waters
Corporation.
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version on businesswire.com: http://www.businesswire.com/news/home/20160307005346/en/
Waters CorporationBrian J. Murphy, +1 508-482-2614Public
Relations ManagerBrian_j_murphy@waters.com
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