By Jonathan D. Rockoff

Pfizer Inc. is scheduled to announce its third-quarter earnings Tuesday morning. Here's what you need to know:

EARNINGS FORECAST: Net income of 55 cents a share is the consensus of analysts surveyed by Thomson Reuters, compared with 58 cents reported during the same period a year earlier. The company hasn't provided guidance for the third quarter, but said in July it expects per-share earnings of $1.47 to $1.62 for the year.

REVENUE FORECAST: Revenue of $12.2 billion is forecast, compared with $12.6 billion reported during the period a year earlier.

WHAT TO WATCH:

--PFIZER DEAL INTEREST: Pfizer talked with at least two companies, AstraZeneca PLC and Actavis PLC, this year about doing a large deal that would lower Pfizer's tax rate. Neither effort succeeded, and the U.S. Treasury Department recently issued rules designed to deter such tax-lowering deals. Has the government's actions driven Pfizer away from pursuing such a deal? Or might Pfizer be interested in a purely strategic-minded big deal?

--COMPANY THINKING ON SPLIT: After shedding its animal-health and nutrition businesses in recent years, Pfizer said it would entertain splitting up the company. Starting this year, Pfizer began breaking out the financials for its three units, a requirement for any split. "What we do eventually will really depend upon how those businesses perform--how our shareholders value those businesses," Pfizer Chief Executive Ian Read said during a second-quarter earnings call in July. How did those businesses perform in the third quarter?

--NEARER-TERM GROWTH DRIVERS. Pfizer's Prevnar pneumonia vaccine was recently recommended for a new use--in adults over the age of 65. Analysts say that could add another $1 billion or more in yearly sales. Will it? The quarter's results might give an early peek. Investors will also listen for any updates on the progress of Pfizer's palbociclib breast-cancer drug, which the Food and Drug Administration is reviewing for approval. Analysts think the drug could have more than $3 billion in yearly sales.

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