By Andy Pasztor 

NASA successfully launched an initial, unmanned version of a capsule on a test flight intended to demonstrate its suitability for human exploration of the solar system in coming decades.

Following a flawless countdown at Cape Canaveral Air Force Station in Florida, a heavy-lift Delta IV rocket lifted the pear-shaped, 11-foot tall Orion spacecraft on the start of its long-awaited inaugural voyage.

Slated to make two orbits around the earth during its nearly five-hour trip, Orion is supposed to reach a maximum altitude of 3,600 miles, nearly 15 times higher than the trajectory of the international space station. The primary goals are to demonstrate the ability of Orion's electronic systems to withstand radiation spikes, and then plummet back to earth to test its heat shield and parachutes.

Unlike Thursday, when uncooperative winds and balky fuel valves prompted a last-minute scrub of the launch, Friday's countdown went smoothly without any delays.

Perched on top of the Air Force's most powerful booster, which generated more than 2 million pounds of thrust at liftoff, the roughly 242-foot tall rocket and its payload arced gracefully into the Florida sky shortly after 7 a.m. Eastern time.

"It's a really exciting day," NASA chief Charles Bolden said before liftoff. "It's a big day for the world, for people who know and like space."

Seconds after liftoff, a NASA launch commentator described it as "the dawn of Orion, and a new era in American space exploration."

Agency experts said the rocket's main engines worked as expected and the second stage ignited on cue, nearly 6 minutes into the flight. With the rocket nearly 120 miles high, the emergency system intended to blast astronauts away from the booster also separated as designed.

Nearly nine minutes into the flight, NASA said the rocket was "functioning perfectly at this point."

From an anticipated speed of 20,000 miles an hour when it first re-enters the atmosphere, the capsule is expected to slow to roughly 17 miles an hour before splashing down in the Pacific about 600 miles southwest of San Diego.

Marc Geyer, NASA's Orion program manager, said the Delta IV's initial firings put the capsule, built by Lockheed Martin Corp., into a "perfect orbit," and "everything is looking great." About an hour into the mission, the rocket's second stage is slated to conduct another burn to help propel the capsule toward its highest point.

Orion is intended to be the centerpiece of the National Aeronautics and Space Administration's human exploration efforts through the 2030s, but funding and policy disagreements cloud its future. Moreover, the capsule almost didn't make it to the launchpad.

U.S. President Barack Obama and his advisers initially moved to abandon the program soon after entering office--when it was set to go to the moon--arguing it was too expensive and would take too long to deploy. When aerospace contractors fumed and Congress balked, NASA's leadership proposed to relegate the mission to a supporting role: serving as a permanent standby rescue vehicle for astronauts to get off the international space station in an emergency.

Finally, some three years ago, after NASA officials and lawmakers reached a hard-fought bipartisan compromise, Orion was reconfigured to become a pathfinder vehicle at the core of NASA's long-term exploration vision. Teamed with a next-generation rocket, dubbed the Space Launch System, NASA envisions Orion carrying substantially more cargo than any previous spacecraft while taking astronauts deeper into space than ever before.

If all goes as planned, Friday's test flight will be the first time since 1972, when Apollo 17 returned from the moon, that a spacecraft built to carry astronauts will venture beyond low-Earth orbit.

NASA anticipates thousands of spectators again jamming roads near the launch complex, as they did Thursday, with local hotels filled and excitement surrounding the mission.

But no matter how well Friday's debut goes, NASA faces years of daunting technical and financial challenges. The overall system could cost more than $20 billion through 2021, which some industry officials said excludes certain operational and other costs.

Orion is set to take astronauts to an asteroid and eventually to Mars, sometime in the late 2030s. However, debate continues to simmer on Capitol Hill and elsewhere about whether astronauts should first take Orion near the moon to perfect propulsion, fueling, life support and other essential technologies.

It is unclear how NASA's budgets--already stretched by the roughly $3 billion cost of its share of operating the international space station--will cover Orion's price tag. Building and testing separate vehicles able to touch down at destinations is likely to cost billions of additional dollars.

A round-trip voyage to the vicinity of Mars could take up to two years. To cope with such rigors, Orion is designed to carry several times as much drinking water, food supplies and propellant than capsules intended to serve the space station or reach other low-Earth orbit destinations.

Faced with budget pressures and continuing congressional uncertainty, the first manned mission may not happen until the beginning of the next decade. After that, NASA's hope is to average roughly one Orion launch a year, but financial issues could significantly stretch out that schedule.

For many space fans, however, Thursday's activities in Florida sparked memories of NASA's heyday, when manned missions to the moon captured the imagination of people around the globe. Part of the reason is that at least from the outside, Orion resembles the craft that transported those lunar explorers.

NASA officials have gone out of their way to stress the parallels and symbolic connections between Orion and the lunar explorations.

NASA and Lockheed have been betting that Friday's events will reinvigorate the agency's manned exploration efforts, as well as prompt other countries to consider participating in long-term Mars missions. Astronaut Rex Walheim, who flew on the last space shuttle and now serves as the astronaut representative to the Orion program, expressed the hopes of many NASA officials. Orion is "another jump from the shuttle program," he said on NASA TV. With renewed talk about ultimate deep-space human missions, he said, "you have that excitement back here at Kennedy Space Center."

Michael Hawes, Lockheed's Orion program manager, said Friday's mission also represents a "test of our whole partnership and organization" working with the agency. Lockheed had an unusually big role in setting up Friday's flight, which cost about $370 million.

Write to Andy Pasztor at andy.pasztor@wsj.com

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