By Chelsey Dulaney 

Johnson & Johnson on Tuesday nudged up its earnings guidance for the year as its second-quarter results modestly topped expectations despite the continued impacts of a strong dollar and competition for its hepatitis C treatment.

J&J said it now expects to post per-share earnings of $6.10 a share to $6.20 a share, up from its previous guidance of $6.04 a share to $6.19 a share. The company is benefiting from growth in its new diabetes and anticlotting treatments, among other items.

Shares, relatively flat over the past three months, edged up 0.7% in premarket trading.

New Brunswick, N.J.-based J&J is facing patent expirations and increased competition for many of its pharma products, such as its hepatitis C treatment Olysio. It also is preparing for the threat of increased competition in the U.S. from lower priced biosimilar versions of its blockbuster anti-inflammatory drug Remicade.

Meanwhile, the strengthening of the U.S. dollar against foreign currencies has hamstrung J&J and many of its health-care peers in recent quarters. J&J said foreign-exchange rates had a negative impact of 7.9% in the quarter.

Overall, J&J's pharmaceutical sales fell 6.6% to $7.9 billion in the quarter, as currency impacts and lower Olysio sales offset 1% operational growth. J&J noted that a number of new drugs helped drive operational growth in the quarter. Its anticlotting treatment Xarelto saw sales surge 30.7% to $472 million, while sales of its Type 2 diabetes treatment Invokana jumped to $318 million from $117 million a year ago.

Sales of its hepatitis C treatments, Olysio and Sovriad, dropped to $264 million from $831 million a year earlier.

Meanwhile, consumer sales fell 7% to $3.5 billion, as a 9.3% currency hit offset 2.3% operational growth. J&J's consumer-health business has been working to recover from a series of recalls of popular over-the-counter medicines including children's Tylenol.

The company said Tuesday that it was helped by sales of Zyrtec allergy medications and Tylenol analgesics.

Excluding acquisitions, divestitures, and hepatitis C sales, J&J's total underlying operational growth was 5% in the quarter.

Overall, J&J reported a profit of $4.52 billion, or $1.61 a share, up from $4.33 billion, or $1.51 a share, a year earlier. Excluding certain items, per-share earnings were $1.71 in the latest quarter.

Revenue fell 8.8% to $17.79 billion.

Analysts polled by Thomson Reuters expected per-share profit of $1.67 and revenue of $17.75 billion.

The company's medical-device business posted a sales decline of 12.2% to $6.36 billion, reflecting an operational decrease of 4.7% and a negative currency impact of 7.5%.

Backing out the impact of acquisitions and divestitures, operational sales growth was 1.4%, helped by sales of endocutters in the surgical care business and joint reconstruction products.

Write to Chelsey Dulaney at Chelsey.Dulaney@wsj.com

Corrections & Amplifications

Johnson & Johnson's Xarelto treatment posted a 30.7% increase in sales in the second quarter, while Invokana sales jumped to $318 million from $117 million a year earlier. An earlier version of this article misstated the increases.

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