By Christopher Alessi 

MUNICH--German engineering giant Siemens AG announced on Thursday an additional 4,500 job cuts world-wide, targeting its embattled power and gas division and a group of underperforming businesses it hopes to turn around.

The new cuts--roughly 2,200 of which are expected to be in Germany--come just months after Siemens said it would reduce its global head count by 7,800, a number it brought down to 7,400 following labor negotiations. The company has also said it would cut around 1,200 jobs in the energy division.

The announcement came as Siemens turned in a sharp improvement in net profit in the quarter to the end of March when proceeds from asset sales and the impact of the weak euro offset shrinking profit margins at its energy and industrial units.

The total of roughly 13,100 job losses is part of a company-wide restructuring led by Chief Executive Joe Kaeser, which includes selling off noncore businesses and focusing more on energy.

"With the initiation of these measures, the company's structural organization has been completed for the most part," Mr. Kaeser said.

Siemens said the job cuts in the power and gas business were a result of a challenging market for power-generation equipment as regulatory changes, falling prices, stiffer competition and overcapacity have plagued Europe's electricity utilities. The other cuts are expected to target a group of unprofitable businesses, including the compressors, transmission and mechanical-drives units.

As part of the restructuring, Mr. Kaeser has sought to sell, partner or turnaround a number of underperforming businesses that comprise around 18% of sales. That effort has included the sale of its health care information technology business for $1.3 billion and a heavy metals joint venture with Mitsubishi Heavy Industries Ltd.

The surge in net profit came largely from gains from the sale of Siemens' stake in a household-appliances joint venture with Robert Bosch GmbH and the disposal of its hearing-aid unit and health care information technology businesses.

Net profit for the period, Siemens' fiscal second quarter, rose to EUR3.89 billion ($4.41 billion) from EUR1.12 billion during the same period last year, beating analysts' expectations. Analysts had forecast a net profit of EUR2.01 billion, according to a recent poll by The Wall Street Journal.

Revenue rose by 8% to EUR18.05 billion from EUR16.7 billion last year, helped by the euro's weakness against major currencies. New orders climbed by 16% to EUR20.75 billion, boosted by large domestic contracts at Siemens' train business.

However, low oil prices and volatile economic conditions in some parts of the world squeezed the group's profitability. The overall industrial profit margin dropped to 9% from 10.3% during the same period last year.

Mr. Kaeser has faced pressure from shareholders to justify Siemens' planned $7.6 billion acquisition of U.S. oil-equipment maker Dresser Rand Group Inc., announced last September. Many analysts and investors have judged the deal as expensive as oil prices have tumbled.

But Mr. Kaeser said on Thursday the deal was still on track to close by this summer as originally planned. "We are quite confident," he said.

Siemens reiterated its guidance for the 2015 fiscal year, saying its expects to attain a profit margin for its industrial businesses between 10% and 11%, a target that many analysts have said Siemens may have trouble achieving in light of continuing economic difficulties.

Write to Christopher Alessi at christopher.alessi@wsj.com

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