NORCROSS, Ga., March 30, 2015 /PRNewswire/ -- A new
proprietary extract called Diosterol™ from Dioscorea Nipponica
Makino has been released in the United
States. Diosterol™ is a Precision Anabolic & Androgenic
extract designed for hard-training athletes who want to get more
out of their workout by boosting Testosterone levels. This potent
plant anabolic is a concentrated (Drug to extract ratio: 5066.7:1)
equal to 10 -13.4 grams of the whole plant. Diosterol™ is
standardized to contain bioactive fractions rich in steroidal
furostanolic saponins and glycosides: Progenin III,
Pseudoprotodioscin, Methyl Protodioscin, Dioscin, Protodioscin,
Iridoid Glycosides, Diosgenin and 5a-Hydroxy Laxogenin. Perhaps the
most potent compound in this state-of-the-art extract is 5a-Hydroxy
Laxogenin. 5a-Hydroxy Laxogenin is the plant-based steroid that can
be extracted from Smilax sieboldii and certain Dioscorea species
and can be synthesized from diosgenin. Due to the complicated
purifying process to identify the active ingredients it takes 2000
lbs of raw Dioscorea to make just 40 lbs of Diosterol™!
Diosterol™ has been clinically HPLC tested to be the strongest
Dioscorea extract for boosting testosterone levels extract in the
world with an average content of over 100 mg of protodioscin per
suggested 250mg dose. The total Furostanol Saponins (active
ingredients) with up to 60%.
Hi-Tech Nutraceuticals, the fastest growing specialty raw
material supplier in the sports nutrition industry, promised to
bring its customers, distributors, and consumers lots of
state-of-the-science ingredients this year. They live up to their
word with the launch of Diosterol™, a proprietary extract meant to
boost testosterone levels. The upcoming release of Diosterol™
represents a monumental addition to a product category that has
been lacking in the industry—especially after the recent
legislation that passed making most prohormones controlled
substances like anabolic steroids. The release of Diosterol™ has
Hi-Tech starting the year strong. As they move into the next
quarter of 2015, Hi-Tech plans to continue to build upon the
success and momentum.
Quality: The herbal preparation is produced under GMP
(Good Manufacturing Practice) conditions. Manufacturing practices
were inspected and approved by 5 Fortune 500 companies and the
factory has certification of GMP, HACCP, CNAS, HALAL, KOSHER and is
now an official member of UNPA and a member in ISC. Control of the
herbal preparation and suitable tests are performed to elucidate
the structure and other characteristics of the herbal extract.
Release specifications for the extract comprise of appearance,
identification by TLC fingerprint, marker content, loss on drying,
residual solvent, pesticides, heavy metals, aflatoxins and
microbiological purity are tested in accordance with Ph. Eur.
Identity is tested in accordance with the monograph of the
Chinese pharmacopoeia.
Manufacture: The starting material is cultivated in the
Henan Province of the People's
Republic of China. The cultivation of the plant and
collection of the plant material are in accordance with the
guideline on Good Agricultural and Collection practice
(EMEA/HMPC/24618/2005).
Precursor for Testosterone Biosynthesis: Steroidal
saponin-containing plant materials gained commercial significance
in 1950s as raw materials for the production of steroid hormones
and drugs. The synthesis of progesterone from the sapogenin
diosgenin obtained from Mexican yam by Marker et al. in 1940s
(Marker et al., 1947) was the beginning of a remarkable era in
steroid research culminating in the synthesis of the first oral
contraceptive in 1951. Diosgenin isolated from Dioscorea species
and to a lesser extent structurally similar sapogenins have been
widely used as raw materials by the steroid industry (Blunden et
al., 1975).
In China and Russia extracts of Dioscorea nipponica Makino
have been on the market for more than 40 years. Extracts of
the roots of Dioscorea nipponica Makino have a long history of
medicinal use in China. The herb
was first recorded in 1959 and in 1977 a monograph of Dioscorea
nipponica Makino was included in the official Chinese
Pharmacopoeia. 5a-Hydroxy Laxogenin was discovered by an American
scientist in 1996. It was shown to possess an anabolic/androgenic
ratio similar to one of the most efficient anabolic substances. It
was shown that 6-ketoderivatives of natural sapogenins display the
anabolic activity and do not manifest any androgenic properties.
Increased testosterone levels are known to increase muscle size and
strength in men with downstream benefits on body weight, body fat,
muscle size, strength, libido, energy, and mood. S. Bhasin,
T.W. Storer, N. Berman, C.
Callegari, B. Clevenger, J. Phillips, et al. The effects of
supraphysiologic doses of testosterone on muscle size and strength
in normal men N Engl J Med, 335 (1996), pp. 1–7
Diosterol™ is the only science-based Dioscorea Nipponica
Makino extract, standardized to a minimum of 40% Protodioscin,
60% Total furostanolic saponins, and 90% total saponins including
Diosgenin and 5a-Hydroxy Laxogenin. Protodioscin acts by
stimulating the enzyme 5-alpha-reductase, which plays a role in the
conversion of testosterone into dihydrotestosterone (Viktorof et
al. 1994). In addition, protodioscin also stimulates the
hypothalamus secretion of luteinizing hormone (LH), but not of
follicle stimulating hormone (FSH). The mechanism of protodioscin's
action causes increases the production of serum testosterone
Most of all, steroidal saponins have been identified as the
bioactive constituents responsible for the anabolic and aphrodisiac
effects, these saponins (of which protodioscin is the primary)
enable the body to produce more testosterone by raising the levels
of the Leuteinizing Hormone (LH), which a hormone released normally
by the pituitary gland helps to maintain testosterone production.
As the LH increases, so testosterone increases.
Diosterol™ is a Precision Anabolic & Androgenic extract
designed for hard-training athletes who want to get more out of
their workout by boosting Testosterone levels — available
only from Hi-Tech Nutraceuticals, LLC.—where science never
stands still™!
CONTACT: Brandon Schopp,
888-855-7919
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SOURCE Hi-Tech Nutraceuticals, LLC.