Regeneron Pharmaceuticals Inc., which recently won approval for its cholesterol drug, said profit doubled in its second quarter as sales of its eye-disease treatment surged.

Shares gained 2.4% in premarket trading.

Tarrytown, N.Y.-based Regeneron commercializes medicines for eye diseases, high cholesterol and a rare inflammatory condition. The company also has a number of other treatments in its pipeline.

Last month, federal regulators approved Praluent, the first of a powerful new class of cholesterol-lowering medicines that Regeneron developed with French drug maker Sanofi SA.

Praluent provides a new option for several million high-risk heart patients who can't get their cholesterol to desirable levels with statin drugs, but it promises to escalate a growing chorus of concern over high drug prices.

Last week, Regeneron and Sanofi announced a new immuno-oncology collaboration, which has been a particularly hot area for cancer treatment development recently.

For the period ended June 30, Regeneron posted a profit of $194.6 million, or $1.69 a share, up from $96.4 million, or 85 cents a share, a year earlier.

Excluding special items, per-share earnings were $2.89 a share, up from $2.47 a share a year earlier.

Revenue jumped 50% to $998.6 million.

Analysts polled by Thomson Reuters had forecast per-share earnings of $2.77 on revenue of $887.8 million.

Product revenue jumped 57% to $657.8 million, as U.S. sales of eye-treatment Eylea grew to $655 million from $415 million a year ago.

Revenue from its Sanofi collaboration grew 37%, while revenue from its collaboration with Bayer HealthCare jumped 38%.

Write to Chelsey Dulaney at Chelsey.Dulaney@wsj.com

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