By Noémie Bisserbe, William Mauldin, Clemens Bomsdorf and Peter Evans 

European and U.S. businesses, from banks to brewers, are blaming hits to their bottom lines on the political uncertainty surrounding Moscow's actions in Ukraine and Russia's worsening economy.

In Europe, where exposure to Russia is far higher, French bank Société Générale SA said Wednesday that its first-quarter net profit fell 13% after it took a EUR525 million ($731.3 million) write-down on its Russian business. Carlsberg A/S and Imperial Tobacco Group PLC both said that falling sales in Russia and a weak ruble had cut profit and would weigh on revenue for the remainder of the year.

In the U.S., multinational companies that sell to consumers say they're getting hit by the steep drop in the ruble, which has cut sales of imported goods ranging from makeup to pharmaceuticals. Others, ranging from satellite operators to financial firms, are directly feeling the pinch of punitive sanctions and other measures that Washington has rolled out to pressure Russian President Vladimir Putin.

European companies have in recent years relied on Russia as a rare engine of growth amid the continent's economic crisis and fitful recovery, making them more vulnerable to Russia's recent economic woes than many U.S. peers.

Those troubles are now being significantly worsened by the political standoff with the West. Many of the specific pressures--a generally softening economy, a weakening currency and tighter regulations of imports like alcohol--were already in play before the crisis. But the standoff, and threat of further economic sanctions against Russia, is now clouding longer-term revenue and earnings forecasts for many big multinationals from both Europe and the U.S.

Maxwell Technologies Inc., which makes chips for satellites that can withstand solar flares, says it has been hit by the U.S. government's decision to withhold export licenses for shipments that have military uses to Russia. The San Diego-based company projected it could lose $2 million in revenue this year without the U.S. export licenses.

Satellite operator Iridium Communications Inc., based in the outskirts of Washington D.C., told investors it hopes to ensure its Russian launches aren't caught up in sanctions. "There is support for a realization that satellites being shipped to Russia to launch from a Russian launch pad is really not export into Russia, but really, frankly just an export through Russia into space," Iridium Chief Executive Matt Desch said.

A spike in political uncertainty and the imposition of targeted sanctions has put further pressure on the ruble and pushed the Russian economy toward recession. More evidence of the decline came on Wednesday, as the HSBC Purchasing Managers' Index, which tracks output of Russia's service providers and manufacturers, contracted in April at its swiftest pace since May 2009.

Société Générale, France's third-largest listed bank by assets, blamed its profit declines on growing political uncertainty, Russia's sluggish economy and weakness of the ruble for the fall. The bank owns one of Russia's largest private lenders, Rosbank.

Jitters in the U.S. have been particularly high in the financial-services sector since the U.S. Treasury Department imposed sanctions in March on Bank Rossiya, which it linked to Mr. Putin and his inner circle.

Visa and MasterCard stopped processing purchases made with cards from Bank Rossiya and its subsidiaries, and Mr. Putin responded by accelerating plans to develop Russia's own national card-payment system. Under new legislation, foreign card processors would have to handle all Russian payments domestically, use a settlement center owned by the central bank, post significant collateral and face potentially large fines.

"I don't think this is a saber-rattling situation any longer, I think this is going to be tough to work for almost everybody, governments and companies, over the next few months or periods of time--it might last longer than that," MasterCard Chief Executive Ajay Banga told investors on a recent conference call.

The big Danish brewer Carlsberg A/S, which generates about a fifth of its revenue in Russia, cited the weak ruble and uncertainty in the country as reasons it swung to an adjusted net loss during the first quarter and forecast a bleaker outlook for the remainder of 2014.

Carlsberg CEO Jorgen Buhl Rasmussen said Wednesday that the company now assumes Russian gross domestic product will be flat for the year on average, "where going into the year we assumed a GDP growth of 1% or 1.5%."

Even before the current crisis in Ukraine, brewers were struggling because of regulatory changes and other factors that pulled the overall Russian beer market down. Anheuser-Busch InBev NV, the world's biggest brewer, said Wednesday that Russian sales in terms of volume fell 10% in the most recent quarter, compared with a 4.5% increase for the group as a whole. Last month, Dutch brewer Heineken NV reported a 37% dip in first-quarter net profit, citing "challenging beer-market conditions in Russia," among other factors.

U.K.-based cigarette giant Imperial Tobacco said Wednesday that Russia--usually one of its fastest-growing markets, where around 40% of the population are smokers--had dragged down first-half earnings. In the past year, the Russian government has banned smoking in many public places, prohibited cigarette sales from street kiosks and raised excise on tobacco products by up to 40%.

"Things are progressing very rapidly in Russia," said Alison Cooper, Imperial's chief executive. Imperial's cigarette volume in Russia declined 7% in the six months ended March 31, and Ms. Cooper said she expects volume to be down around 10% over the full year.

Unilever PLC, the world's second-largest consumer-goods maker, is among the corporate players blaming the ruble's weakness for recent struggles. The company recently surpassed EUR1 billion in sales in Russia, having entered the country in 1992, but has seen many of its gains in the past year wiped out by the ruble's slide. Global sales in Unilever's most recent quarter fell 6.3%.

Veronika, Gulyas,

Jens Hansegard

, Ruth Bender and Christina Passariello contributed to this article.

Write to Noémie Bisserbe at noemie.bisserbe@wsj.com, Clemens Bomsdorf at clemens.bomsdorf@wsj.com and Peter Evans at peter.evans@wsj.com

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