FORM 4
[ X ] Check this box if no longer subject to Section 16. Form 4 or Form 5 obligations may continue. See Instruction 1(b).         
UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549

STATEMENT OF CHANGES IN BENEFICIAL OWNERSHIP OF SECURITIES
                                                                                  
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Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934 or Section 30(h) of the Investment Company Act of 1940
                      

1. Name and Address of Reporting Person *

QVT Associates GP LLC
2. Issuer Name and Ticker or Trading Symbol

AGENUS INC [ AGEN ]
5. Relationship of Reporting Person(s) to Issuer (Check all applicable)

_____ Director                      __ X __ 10% Owner
_____ Officer (give title below)      _____ Other (specify below)
(Last)          (First)          (Middle)

1177 AVENUE OF THE AMERICAS, 9TH FLOOR
3. Date of Earliest Transaction (MM/DD/YYYY)

1/9/2015
(Street)

NEW YORK, NY 10036
(City)        (State)        (Zip)
4. If Amendment, Date Original Filed (MM/DD/YYYY)

 
6. Individual or Joint/Group Filing (Check Applicable Line)

___ Form filed by One Reporting Person
_ X _ Form filed by More than One Reporting Person

Table I - Non-Derivative Securities Acquired, Disposed of, or Beneficially Owned
1.Title of Security
(Instr. 3)
2. Trans. Date 2A. Deemed Execution Date, if any 3. Trans. Code
(Instr. 8)
4. Securities Acquired (A) or Disposed of (D)
(Instr. 3, 4 and 5)
5. Amount of Securities Beneficially Owned Following Reported Transaction(s)
(Instr. 3 and 4)
6. Ownership Form: Direct (D) or Indirect (I) (Instr. 4) 7. Nature of Indirect Beneficial Ownership (Instr. 4)
Code V Amount (A) or (D) Price
Common Stock, $0.01 par value   1/9/2015     S    20000   D $5.55   9239260   I   Through QVT Fund IV LP, QVT Fund V LP and Quintessence Fund L.P.  
Common Stock, $0.01 par value   1/9/2015     S    143900   D $5.30   9095360   I   Through QVT Fund IV LP, QVT Fund V LP and Quintessence Fund L.P.  
Common Stock, $0.01 par value   1/9/2015     S    146394   D $5.27   8948966   I   Through QVT Fund IV LP, QVT Fund V LP and Quintessence Fund L.P.  
Common Stock, $0.01 par value   1/9/2015     S    53606   D $5.21   8895360   I   Through QVT Fund IV LP, QVT Fund V LP and Quintessence Fund L.P.  
Common Stock, $0.01 par value   1/9/2015     S    400000   D $5.62   8495360   I   Through QVT Fund IV LP, QVT Fund V LP and Quintessence Fund L.P.  
Common Stock, $0.01 par value   1/9/2015     S    215000   D $5.19   8280360   I   Through QVT Fund IV LP, QVT Fund V LP and Quintessence Fund L.P.  
Common Stock, $0.01 par value   1/9/2015     S    856920   D $5.18   7423440   I   Through QVT Fund IV LP, QVT Fund V LP and Quintessence Fund L.P.  
Common Stock, $0.01 par value   1/9/2015     S    43080   D $5.57   7380360   I   Through QVT Fund IV LP, QVT Fund V LP and Quintessence Fund L.P.  
Common Stock, $0.01 par value   1/9/2015     S    100000   D $5.20   7280360   I   Through QVT Fund IV LP, QVT Fund V LP and Quintessence Fund L.P.  
Common Stock, $0.01 par value   1/9/2015     S    50000   D $5.44   7230360   I   Through QVT Fund IV LP, QVT Fund V LP and Quintessence Fund L.P.  
Common Stock, $0.01 par value   1/9/2015     S    89800   D $5.49   7140560   I   Through QVT Fund IV LP, QVT Fund V LP and Quintessence Fund L.P.  
Common Stock, $0.01 par value   1/9/2015     S    100000   D $5.35   7040560   I   Through QVT Fund IV LP, QVT Fund V LP and Quintessence Fund L.P.  
Common Stock, $0.01 par value   1/9/2015     S    83100   D $5.31   6957460   I   Through QVT Fund IV LP, QVT Fund V LP and Quintessence Fund L.P.  
Common Stock, $0.01 par value   1/9/2015     S    41830   D $5.33   6915630   I   Through QVT Fund IV LP, QVT Fund V LP and Quintessence Fund L.P.  

Table II - Derivative Securities Beneficially Owned ( e.g. , puts, calls, warrants, options, convertible securities)
1. Title of Derivate Security
(Instr. 3)
2. Conversion or Exercise Price of Derivative Security 3. Trans. Date 3A. Deemed Execution Date, if any 4. Trans. Code
(Instr. 8)
5. Number of Derivative Securities Acquired (A) or Disposed of (D)
(Instr. 3, 4 and 5)
6. Date Exercisable and Expiration Date 7. Title and Amount of Securities Underlying Derivative Security
(Instr. 3 and 4)
8. Price of Derivative Security
(Instr. 5)
9. Number of derivative Securities Beneficially Owned Following Reported Transaction(s) (Instr. 4) 10. Ownership Form of Derivative Security: Direct (D) or Indirect (I) (Instr. 4) 11. Nature of Indirect Beneficial Ownership (Instr. 4)
Code V (A) (D) Date Exercisable Expiration Date Title Amount or Number of Shares

Explanation of Responses:

Remarks:
On January 9, 2015, Quintessence Fund L.P. sold 216,080 shares of Common Stock, QVT Fund IV LP sold 302,334 shares of Common Stock and QVT Fund V LP sold 1,825,216 shares of Common Stock. As a result, Quintessence Fund L.P. directly beneficially owns 637,610 shares of Common Stock, QVT Fund IV LP directly beneficially owns 892,132 shares of Common Stock and QVT Fund V LP directly beneficially owns 5,385,888 shares of Common Stock. QVT Associates GP LLC is the general partner of QVT Fund IV LP, QVT Fund V LP and Quintessence Fund L.P. (together with QVT Fund IV LP, and QVT Fund V LP, the "Funds"). QVT Financial LP is the investment manager for the Funds and therefore may be deemed the beneficial owner of the Common Stock held by the Funds. QVT Financial GP LLC is the general partner of QVT Financial LP and therefore may be deemed the beneficial owner of Common Stock beneficially owned by QVT Financial LP. The reporting person disclaims beneficial ownership of the reported securities except to the extent of its pecuniary interest therein.

Reporting Owners
Reporting Owner Name / Address
Relationships
Director 10% Owner Officer Other
QVT Associates GP LLC
1177 AVENUE OF THE AMERICAS, 9TH FLOOR
NEW YORK, NY 10036

X

QVT Fund V LP
1177 AVENUE OF THE AMERICAS, 9TH FLOOR
NEW YORK, NY 10036

X


Signatures
/s/ Tracy Fu, Managing Member 1/13/2015
** Signature of Reporting Person Date


Reminder: Report on a separate line for each class of securities beneficially owned directly or indirectly.
* If the form is filed by more than one reporting person, see Instruction 4(b)(v).
** Intentional misstatements or omissions of facts constitute Federal Criminal Violations. See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a).
Note: File three copies of this Form, one of which must be manually signed. If space is insufficient, see Instruction 6 for procedure.
Persons who respond to the collection of information contained in this form are not required to respond unless the form displays a currently valid OMB control number.
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