By Annie Gasparro 

Kraft Heinz Co. said it is cutting 2,500 jobs in North America--more than 5% of its global workforce--as it aims to slash at least $1.5 billion from the newly combined company's annual budget.

Kraft Foods Group Inc. and H.J. Heinz Co. merged last month in a deal orchestrated by Heinz owners 3G Capital Partners LP and Berkshire Hathaway Inc.'s Warren Buffett.

Now that the integration is under way, a Kraft Heinz spokesman said Wednesday that its new management team--led primarily by legacy Heinz executives and 3G officials--has restructured the company to simplify its operations and leverage its much larger scale. "This new structure eliminates duplication to enable faster decision-making, increased accountability and accelerated growth," the spokesman said.

As part of that process, the company, with about $28 billion in annual revenue, will eliminate 2,500 jobs in the U.S. and Canada, including 700 employees in its Chicago-area headquarters in Northfield, Ill. The company has a second headquarters in Pittsburgh.

Kraft said it had roughly 2,300 employees at the sprawling corporate campus when it announced plans to merge with Heinz in March, but the new company said Wednesday its latest head count there was 1,900.

Kraft employees and others who follow the industry anticipated significant job reductions and sweeping cost-cutting at the new company. 3G, a Brazilian investment firm, is known for an aggressive focus on costs and eliminated many jobs at Heinz after it took over the ketchup maker in 2013.

The Kraft Heinz spokesman wouldn't say where the remaining 1,800 jobs cuts are coming from, but said they are all salaried employees.

Kraft Heinz, like other big food companies, faces an uphill battle to boost sales with conventional packaged foods that are losing traction as U.S. consumers seek out fresher food with simpler ingredients. The Kraft Heinz stable includes Velveeta cheese, Jell-O desserts and frozen Bagel Bites.

For the quarter leading up to their merger, Kraft and Heinz each reported sales declines, but the company didn't provide a further outlook on the business, which is the fifth-largest food company in the world by sales.

Wednesday's announced layoffs weren't the first time Kraft employees have felt the impact of their new owners. Days before the merger was completed, the predecessor companies announced that Heinz executives would take over eight of the top 10 positions at the combined company.

And last month, Kraft Heinz said it planned to move the Kraft employees from the suburbs to a downtown Chicago office space that is about one-fourth the size of the Northfield offices.

Write to Annie Gasparro at annie.gasparro@wsj.com

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