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Caribou Biosciences Inc

Caribou Biosciences Inc (CRBU)

2.02
0.14
(7.45%)
Closed July 14 4:00PM
2.00
-0.02
(-0.99%)
After Hours: 7:37PM

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Monksdream Monksdream 2 weeks ago
CRBU new 52 week low
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Monksdream Monksdream 4 weeks ago
CRBU new 52 week low
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NY1972 NY1972 4 weeks ago
Without engaging macrophage long term, CART and other ACT will have persistence issue as regulatory lymphocytes and TAM recoup. AFMD has the best approach with ICE engaging a few B CBNK cells for start and engaging endogenous NK and M in the maintenance phase
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Diego Rivas Diego Rivas 1 month ago
Any good news in here comming?
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jondoeuk jondoeuk 1 month ago
Among patients with four or more matching HLA alleles, mPFS was 14.4 months, versus 2.8 months in patients with three or fewer matches. But this is based on a retrospective analysis, so they will need to prove the theory prospectively. It was better in LBCL, with mPFS not reached, versus 2.8 months. Also, some improvement in the now-selected dose, 80 million CAR-T cells.
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jondoeuk jondoeuk 1 month ago
The BCMA-targeted space is already crowded enough and off-target toxicities, including agranulocytosis* could be a problem for its anti-CLL-1 CAR.

* CLL-1 is also highly expressed on almost all granulocytes and monocytes and on parts of myeloid progenitors in the normal bone marrow and peripheral blood.
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Monksdream Monksdream 1 month ago
CRBU new 52 week low
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stocksrising stocksrising 1 month ago
Yep, not a positive trend hence sub $3’s…fortunately other trials for varied indications could save company…
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jondoeuk jondoeuk 1 month ago
It gets worse. The updated (CB-010) data shows that the ORR (including CR rate) has fallen, so has the mDOR, the six-month PFS is poor and the pivotal trial has been delayed until H2 2025 following a new HLA partial matching strategy. The latter completely alters (in a bad way) the commercial strategy for an allo CAR-T product. They now need thirteen different off-the-shelf batches to be able to cater to ~90% of patients based on an ideal HLA match.
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Monksdream Monksdream 2 months ago
CRBU new 52 week low
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Monksdream Monksdream 2 months ago
CRBU new 52 week low
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Monksdream Monksdream 3 months ago
CRBU under $5
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stocksrising stocksrising 4 months ago
It seemed like they were running on all positive cylinders, but must have blown a gasket at current Conference/ Fireside???
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Monksdream Monksdream 9 months ago
CRBU new 52 week low
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jondoeuk jondoeuk 12 months ago
Yes, with both drugs still in development. As for CRBU, they gave an update (plus public offering) https://finance.yahoo.com/news/caribou-biosciences-reports-positive-clinical-200100822.html https://investor.cariboubio.com/static-files/d818ed1a-aea2-41c1-84ea-bd05a4276cbb

Personally, there seem to be red flags, such as no expansion/persistence data. I know they give huge amounts of LD chemo, higher (I think) than anyone else, which could be generating responses, explaining why there is no dose response.
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trueblue trueblue 1 year ago
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trueblue trueblue 1 year ago
$23.00 price target! Now that is a good start!! Glad I loaded up! Jmo
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NY1972 NY1972 1 year ago
Didn't they buy TRIL? Just gambling with billions from US government.
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jondoeuk jondoeuk 1 year ago
PFE is very selective in who they fund https://finance.yahoo.com/news/caribou-biosciences-announces-25-million-120000433.html
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trueblue trueblue 1 year ago
Great day in my accounts again! Really liking my CRBU shares! Jmo holding for the long haul!!
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Monksdream Monksdream 1 year ago
CRBU now No 9 on the Barchart Top 10
https://www.barchart.com/stocks/performance/percent-change/advances?timeFrame=today&viewName=main&screener=overall&orderBy=percentChange&orderDir=desc
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trueblue trueblue 1 year ago
Added to my existing shares today, I bought shares months ago. I like Crbu a crisper company! Looks like Pfizer does also! Jmo
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Stockexpertpro Stockexpertpro 1 year ago
CRBU Loss 108 Million Dollars Company only has preclinical and phase 1 in its pipeline company is Years away from having anything if ever did a stock offering at 5.33$ for 25 Million thats only 1 QTR Cash burn for this company Sell the News https://www.cariboubio.com/pipeline/
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TheFinalCD TheFinalCD 1 year ago
CRBU= JUST WOW

https://finviz.com/quote.ashx?t=CRBU&ty=c&ta=1&p=d
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Monksdream Monksdream 1 year ago
CRBU No 1 on the early Barchart Top 100
https://www.barchart.com/stocks/performance/percent-change/advances?timeFrame=today&viewName=main&screener=overall&orderBy=percentChange&orderDir=desc
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