Monopar Therapeutics Inc (MNPR) Quote

who killed the radiostar?
looking very great down here

Stock up 50% recently. Quietly moving higher.
They will report some data soon. Running in anticipation?
I like this stock a lot.
I think it has more to go.
JMO

https://investorshub.advfn.com/boards/read_msg.aspx?message_id=173913331

MNPR................................................https://stockcharts.com/h-sc/ui?s=MNPR&p=W&b=5&g=0&id=p86431144783

MNPR: And let alone try to explain that sudden (late-day) circa 240% soaring by @OCEA!!! And when one searches iHub's "ALL POSTS" about OCEA, one gets ambiguous posts about "Reddit was all over it", & "One guy threw $300,000 at it". BOY, that sure explains it all!!! (BONKERS STUFF, Bro!!)

If there really is 15 million shares OS...That could explain the run...Granted it is a Day 2 on a Friday,the Run fizzled

Wow it just crashed....idk what's next

Gamma squeeze

Still strong

MNPR: So am I, Dude!! NOTHING anymore makes any reasonable sense at all!!! (Their cheap FLUFF "news" of yesterday --- a mere Pre-Clinical Cancer stuff routine --- was patently UN-impressive at its core!! Yet today it soars!!)

Off to a bad Start...surprised there isn't any posters,on this board...Some wild moves in either direction

#MNPR 🔥 gap fill to $2-$3 coming? Big upside! $MNPR

How many shares OS?

A lot of dumping

Spring tight ready for 1.5

Yup keeps popping off trend line

MNPR: You yourself have posted this sentiment countless times, Boss!!! NONE of this 'Wall Street' stuff makes ANY (rational) sense at all!!!

yep and still goin

MNPR: The obvious WINNER of this day!!! (And all behind a mere PHASE-1 Cancer study routine!!! How the fluck can anyone call this stuff???!!!)

Level 2 just switched bullish

Monopar Announces Promising Preclinical Data for its MNPR-101 Radiopharma Program Targeting Advanced Cancers

MNPR: WOW!! I hear-ya behind ALL of those notes, Boss!!! (And heck, I wouldn't mind being YOUR son --- his favorite 'WHEELS' is that red VET, no doubt??? Or, he's already FLIPPED a stock by himself, & bought his OWN Vet??? Naturally!!!)

OH IVE BEEN BURNT BAD BEFORE

I WAS JUST TELLING MY 17YR OLD SON WHO I AM TEACHING HIM ABOUT THE MARKET

I TOLD HIM I LOST -$80K ON A PHASE 1 THAT GAPPED AND TRAPPED ME AND SO MANY OTHERS

THAT WAS BRUTAL


AND I DID IT A FEW TIMES AFTER, THEN GAVE UP ON PHASE 1 STOCKS

💪🏿

MNPR: Well then, CONGRATS to ya, Dude!!! (& GOD BLESS!!!)

Yet n still I made money. You're expecting to much.

Just take your profits n let it be. Arguing about it isn't gonna change that.the price is going back up
N my free shares looking good

Learn to have fun. Not cry. We know companies send out pr to stop the bleeding n gain investors attention

That's why we invest.we don't marry. Everyone wants money.

Take it accordingly

Good day sir. I'm off to the next investment

MNPR: There was NOTHING to be made in the Pre-Market, either, Clown behind this scam!!! In case you didn't know that!!!

Took original plus extra holding a few for just in case.

That's how u trade

Riding free shares

Smh 🤦🏿‍♂️ HOMEBOY

You missed the point. Keep up.. Best bet is to trade with the big boys premarket in sell at open

Or buy after hours sell at premarket or open.

Flip in the case of last minute pr

Stop looking for a reason to argue

No one will listen to your rubbish

We don't need your explanation. Just say what you gotta say n leave it at that

MNPR: Myself, I am NOT "embarrassed", because I wasn't dumb enough to even THINK about buying this baloney sandwich (Pre-Colombian-Technology) "News". And certainly YOU --- Admiral TFCD --- weren't stupid enough either.

MNPR: And that "bet" is now OVER, Homeboy!! (Cheap --- merely Phase-1 "news" --- & still hyping old RADIATION gadgets!!! Stay AWAY from this kind of Pre-Colombian medical "technology"!!!)

Best bet

MNPR: This type of LAST MINUTE news is deliberately launched as such --- as if everyone doesn't yet know that. (HA-HAAAA!! Flip it really QUICK, if ya all grabbed some of this clever PR launch!!)

We will see

I hate when halts. Its gonna one of those days

Instituionals halting to take profit

It willhold for while think we see 1000% minimum

I was hoping for 50$ runner on strength n hype.but if they keep halting it we will see 10 -15$

LETS SEE IF THIS HOLDS OR ANOTHER ALL DAY FADER???

👀 very

Premarket is always where the big money buy and sell.
We must trade accordingly.

This is no different. Just gott get in where we fit in

ITS FLYING BUT BE CAREFUL iVE LOST SO MUCH $$$$ ON PHASE 1 PREMARKET PUMPS

IM EMBARRASSED



https://www.globenewswire.com/news-release/2024/02/20/2831765/0/en/Monopar-Receives-Clearance-to-Proceed-with-First-in-Human-Phase-1-Trial-of-Novel-Radiopharmaceutical-MNPR-101-Zr-in-Advanced-Cancers.html

Wild

Could be an interesting opener. Very good news lets see how the crowd reacts.

Some interest premarket

Might see nice jump at open with these cheap prices

Monopar Receives Clearance to Proceed with First-in-Human Phase 1 Trial of Novel Radiopharmaceutical MNPR-101-Zr in Advanced Cancers

Monopar Presents Data Showing Tumor Reduction Benefit of Camsirubicin from Ongoing Phase 1b at the 2023 Connective Tissue Oncology Society (CTOS) Annual Meeting
WILMETTE, Ill., Nov. 01, 2023 (GLOBE NEWSWIRE) -- Monopar Therapeutics Inc. (Nasdaq: MNPR), a clinical-stage biopharmaceutical company focused on developing proprietary therapeutics designed to extend life or improve the quality of life for cancer patients, will present data from its ongoing Phase 1b open-label, dose-escalating clinical trial of camsirubicin in patients with advanced soft tissue sarcoma (ASTS) later today at the 2023 Connective Tissue Oncology Society (CTOS) Annual Meeting, which is bringing together the world’s leading sarcoma specialists. Monopar’s poster presentation can be found at the following link: https://www.monopartx.com/pipeline/Camsirubicin/mnpr-201-001-clinical-trial.

Clinical Trial Results To-Date

The Phase 1b clinical trial has enrolled 14 ASTS patients (9 female and 5 male) to-date ranging in age from 26 to 81 years (median = 52.5 years) across five dose cohorts. The trial is currently ongoing and is in the fifth dose level cohort (650 mg/m2).

So far, 9 out of the 14 patients have had stable disease (SD, as defined by RECIST 1.1 criteria) after camsirubicin treatment. All patients in the fourth and fifth cohorts achieved stable disease, including the three most recently treated patients, each of whom also experienced an ~20% tumor size reduction at last study scan. One of these patients had unresectable cancer at study entry, but after the tumor size reduction, the patient became eligible for resection and underwent successful surgical removal of their cancer with clear margins.

No dose-limiting toxicity, as defined in the protocol, has been observed to-date. A medically complex patient in the 650 mg/m2 dose cohort has an ongoing left ventricular ejection fraction (LVEF) decrease that is being monitored. This patient has a BMI of 42.5, one kidney, hypertension, a long standing heart murmur, and a maternal history of heart failure. No toxicities have occurred requiring expansion of a dose cohort, and the maximum tolerated dose (MTD) has not been reached.

Camsirubicin Background

ASTS is a deadly cancer with inadequate treatment options. Doxorubicin is currently the first-line standard of care treatment for most types of ASTS, and the average life expectancy from time of diagnosis for these patients is only about 12 to 15 months. Because of the risk of irreversible heart damage, patients discontinue doxorubicin treatment after just 6 to 8 cycles. Camsirubicin was designed to retain the anti-cancer activity while avoiding the irreversible heart damage that is seen with doxorubicin. The value-driving hypothesis for camsirubicin is straightforward: modifying doxorubicin to reduce cardiac damage could enable both higher and longer dosing, resulting in better efficacy and patient outcomes.

MNPR new 52 week low

MNPR new 52 week low

Monopar Provides Encouraging Camsirubicin Clinical Data Update
WILMETTE, Ill., Aug. 08, 2023 (GLOBE NEWSWIRE) -- Monopar Therapeutics Inc. (Nasdaq: MNPR), a clinical-stage biopharmaceutical company focused on developing innovative treatments for cancer, today provided an update from its currently enrolling multi-center open-label Phase 1b clinical trial of camsirubicin in patients with advanced soft tissue sarcoma (ASTS). Both patients treated to date at the 650 mg/m2 dose level have experienced tumor size reductions – of 18% and 20% respectively – after the first two cycles of camsirubicin treatment. Both patients are set to receive additional cycles of camsirubicin treatment, as well, which may result in further tumor size reduction.

The Phase 1b clinical trial data is continuing to support Monopar’s dose-response hypothesis with camsirubicin. The best response seen prior to the current 650 mg/m2 dose level was at the immediately prior dose level (520 mg/m2), which was a 21% reduction in tumor size in a patient after receiving six cycles of camsirubicin treatment. This patient’s cancer was unresectable at study entry, but after the tumor size reduction, became eligible and the patient underwent successful surgical removal of their cancer with clear margins. Furthermore, all three patients at the 520 mg/m2 dose level achieved stable disease and had either a net reduction or no overall change in tumor size per RECIST 1.1 while on study drug.

Additionally, no drug­related cardiotoxicity has been observed in the trial to date as evaluated by the industry standard left ventricular ejection fraction (LVEF), and no toxicities have been experienced by any patient that have required expanding the size of a dose cohort. Further, 71% of camsirubicin patients have experienced no hair loss, and only approximately 14% have experienced >50% hair loss, with the remainder having low grade hair loss. This compares favorably to the approximately 50% of doxorubicin treated patients in recent ASTS clinical trials reporting some amount of hair loss, with the majority of these patients experiencing >50% hair loss. Only 14% of camsirubicin patients in the Phase 1b trial have experienced mild-to-severe oral mucositis. This compares favorably to the roughly 35-40% of doxorubicin-treated patients in recent ASTS clinical trials that experienced mild-to-severe oral mucositis.

ASTS is a deadly cancer with inadequate treatment options. Doxorubicin is currently the first-line standard of care treatment for most types of ASTS, and the average life expectancy from time of diagnosis for these patients is only about 12 to 15 months. Because of the risk of irreversible heart damage, patients discontinue doxorubicin treatment after just 6 to 8 cycles. Camsirubicin has been designed to retain the anti-cancer activity while avoiding the irreversible heart damage that is seen with doxorubicin. The value-driving hypothesis for camsirubicin is straightforward: modifying doxorubicin in order to reduce cardiac damage could enable higher and longer dosing, resulting in better efficacy and patient outcomes.

Camsirubicin Clinical Trial Design and GEIS Collaboration

The purpose of this dose escalation Phase 1b trial is to determine the maximum tolerated dose (MTD) of camsirubicin. Once the MTD is reached, Monopar has a clinical collaboration agreement in place with the Spanish Sarcoma Group (Grupo Español de Investigación en Sarcomas, or GEIS) to conduct a multi-country randomized Phase 2 clinical trial. The Phase 2 plan is to evaluate camsirubicin head-to-head against doxorubicin in patients with ASTS, with GEIS as the study sponsor with support from Monopar.

Further information about this actively enrolling, open-label, dose-escalation Phase 1b clinical trial is available at www.ClinicalTrials.gov under study identifier NCT 05043649.

About Monopar Therapeutics Inc.

Monopar Therapeutics is a clinical­stage biopharmaceutical company focused on developing innovative treatments for cancer patients. Monopar's pipeline consists of camsirubicin (Phase 1b) for the treatment of advanced soft tissue sarcoma; MNPR­101, a late­stage preclinical antibody for radiopharmaceutical use in advanced cancers; and MNPR­202, an early­stage camsirubicin analog for various cancers. For more information, visit: www.monopartx.com.

Forward-Looking Statements

Statements contained in this press release regarding matters that are not historical facts are "forward-looking statements" within the meaning of the Private Securities Litigation Reform Act of 1995. The words “may,” “will,” “could,” “would,” “should,” “expect,” “plan,” “anticipate,” “intend,” “believe,” “estimate,” “predict,” “project,” “potential,” “continue,” “target” and similar expressions are intended to identify forward-looking statements, although not all forward-looking statements contain these identifying words. Examples of these forward-looking statements include statements concerning: that additional cycles of camsirubicin treatment may result in further tumor size reduction; that the hypothesis for camsirubicin is straightforward: modifying doxorubicin in order to reduce cardiac damage could enable higher and longer dosing, resulting in better efficacy and patient outcomes; and Monopar’s plans to conduct a multi-country randomized Phase 2 clinical trial once the MTD is reached evaluating camsirubicin head-to-head against doxorubicin in patients with ASTS, with GEIS as the study sponsor with support from Monopar. The forward-looking statements involve risks and uncertainties including, but not limited to: the camsirubicin Phase 1b trial not proving safety and efficacy at higher doses; not successfully recruiting additional patients and initiating additional clinical trial sites for the camsirubicin Phase 1b clinical trial within expected timeframes, if at all; the Company’s inability to raise sufficient funds or engage a partner to continue the camsirubicin clinical program beyond the Phase 1b clinical trial; GEIS not conducting the camsirubicin Phase 2 clinical trial; and the significant general risks and uncertainties surrounding the research, development, regulatory approval, and commercialization of therapeutics. Actual results may differ materially from those expressed or implied by such forward-looking statements. Risks are described more fully in Monopar's filings with the Securities and Exchange Commission. All forward-looking statements contained in this press release speak only as of the date on which they were made. Monopar undertakes no obligation to update such statements to reflect events that occur or circumstances that exist after the date on which they were made. Any forward-looking statements contained in this press release represent Monopar’s views only as of the date hereof and should not be relied upon as representing its views as of any subsequent date.

CONTACT:??

Monopar Therapeutics Inc.
Investor Relations??
Kim R. Tsuchimoto??
Chief Financial Officer??
kimtsu@monopartx.com

Follow Monopar on social media for updates:?
Twitter: @MonoparTx? LinkedIn: Monopar Therapeutics

https://www.globenewswire.com/newsroom/ti?nf=ODg4OTAzMyM1NzQxNzkxIzIxOTM4NjM=
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Source: Monopar Therapeutics Inc.
© 2023 GlobeNewswire, Inc.

$MNPR - 👆Up 9.9% Pre-Market/ Current Price $0.83
Monopar Provides Encouraging Camsirubicin Clinical Data Update

1.00 right now

MNPR new 52 week low