axelvento
2 hours ago
the Company will present data from its respiratory portfolio, including vaccines and vaccine candidates against COVID-19 (mRNA-1273, mRNA-1283), influenza (mRNA-1010, mRNA-1011/1012), and respiratory syncytial virus (RSV) (mRNA-1345), along with data related to its latent virus portfolio regarding cytomegalovirus (CMV), at the European Society of Clinical Microbiology and Infectious Diseases (ESCMID) Global Congress in Barcelona, Spain, from April 27-30, 2024.
https://investors.modernatx.com/news/news-details/2024/Moderna-To-Present-Respiratory--Cytomegalovirus-Research-at-the-ESCMID-Global-Congress/default.aspx
axelvento
16 hours ago
Should You Buy Moderna Before May 12?
Though GSK and Pfizer both got a head start in this market, Moderna could carve out market share and eventually take a leadership position for two reasons. First, mRNA-1345 is the only one to come in a pre-filled syringe format. This makes it easier and faster for healthcare providers to administer, and results in fewer errors. All of this is a big plus for those giving the vaccine and those receiving it.
Second, in the phase 3 clinical trial of mRNA-1345, Moderna didn't observe cases of Guillain-Barre syndrome, a rare neurological disorder. But GSK and Pfizer both reported cases of this autoimmune condition in their trials. Some doctors, seeing this data, may recommend the Moderna product to their patients over others.
https://www.fool.com/investing/2024/04/26/should-you-buy-moderna-before-may-12/
axelvento
3 weeks ago
mRNA drug offers hope for treating a devastating childhood disease
Nassrine Fawaz in Livonia, Michigan, has witnessed a transformation in her 4-year-old daughter, who has received mRNA-3927 for the past 2.5 years. After each infusion, โsheโs focused, sheโs energetic, sheโs up and ready for the day โ all of those great thingsโ.
https://www.nature.com/articles/d41586-024-00954-4
XenaLives
4 weeks ago
Really lame....
Prevention sounds like a better option.
I researched the flu vaccines in the early '90s and will not take them either.
The only vaccine I would consider is tetanus after an injury.
Epstein Barr virus (EBV) is a herpesvirus in which over 90% of the population worldwide has been infected.
https://www.ncbi.nlm.nih.gov/books/NBK559285
AI summary:
Yes, some chemotherapeutic drugs
can cause Epstein-Barr virus (EBV) infection in latently infected cells. These drugs include: Gemcitabine, Doxorubicin, Cis-platinum, and 5-fluorouracil.
EBV
can also be reactivated by drug-induced hypersensitivity syndrome (DRESS), which is a severe reaction to certain drugs. DRESS is characterized by: Fever, Skin eruption, Cervical lymphadenopathy, Leukocytosis with atypical lymphocytosis and/or eosinophilia, and Liver dysfunction.
Anticonvulsants
and antimicrobial agents are some drugs that can cause DRESS. For example, allopurinol and carbamazepine have been associated with EBV reactivation.
Some drugs can also inhibit EBV replication in vitro, including:
Acyclovir, Desiclovir, Ganciclovir, Interferon-alfa, Interferon-gamma, Adenine arabinoside, and Phosphonoacetic acid.
Medscape Reference
Pediatric Mononucleosis and Epstein-Barr Virus Infection ...
3 days ago โ Class Summary. Numerous drugs inhibit Epstein-Barr virus replication in vitro. These include acyclovir, desciclovir, ganciclovir, interferon-alfa, interferon-gamma, adenine arabinoside, and phosphonoacetic acid. Acyclovir, which inhibits viral shedding from the oropharynx, is the only antiviral drug used to treat infectious mononucleosis in placebo-controlled clinical trials. However, the clinical course is not significantly affected in patients with uncomplicated infectious mononucleosis.
EBV is best known for causing mononucleosis , but it can also lead to other diseases, including: Ear infections and diarrhea in children
Guillain-Barre syndrome Certain cancers, including Burkitt's lymphoma and cancers of the nose and throat Post-transplant lymphoproliferative disease (PTLD)
This is for informational purposes only. For medical advice or diagnosis, consult a professional.
So if you have a 90% chance of having latent EBV why would you or your physician risk these drugs?
I speak from experience - I was poisoned by Cipro, a fluroquinolone. I died.... and I was given this lethal antibiotic for a FUNGAL INFECTION.
Anticonvulsant Hypersensitivity Syndrome Associated with Epstein-Barr Virus Reactivation
Jae Yong Chang and Soo-Chan Kim corresponding author
We describe a 59-year-old female with severe anticonvulsant hypersensitivity syndrome (AHS) associated with Epstein-Barr virus (EBV) infection. The causative drug was speculated to be carbamazepine. Recurrent EBV infection was demonstrated by the presence of anti-EBV early antigen IgM antibodies and anti-EBV nuclear antigen IgG antibodies. To our knowledge, only one case of drug hypersensitivity syndrome (DHS) associated with EBV has been reported in the English-language literature. Our case is the second report of EBV-associated DHS, which suggests that EBV infection may contribute to the pathogenesis of AHS in a few patients.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2628108/