International stocks trading in New York were mixed on Thursday. The BNY Mellon index of American depositary receipts fell 0.4% to 145.52. The European index increased 0.5% to 143.28, the Asian index dropped 0.5% to 145.71, the Latin American index rose 0.2% to 258.96 and the emerging markets index increased 0.2% to 281.96. Among the companies with shares that actively traded was Sanofi (SNY).

At a widely anticipated meeting to review its pipeline, Sanofi offered sobering news about its global diabetes business, which is expected to yield flat to slight growth between 2015 and 2018. The Paris-based pharmaceutical company's shares fell 3.2% to $46.57.

U.K. regulators on Thursday fined Royal Bank of Scotland Group PLC (RBS, RBS.LN) 56 million British pounds ($87.8 million) for a 2012 computer failure that saw millions of customers unable to access their accounts. Shares fell 1.2% to $11.93.

Royal Dutch Shell PLC (RDSA, RDSB.LN) said Thursday that it has sold its stake in a set of oil wells and processing plants in Nigeria's Niger Delta, the latest in a series of sales in an area where Shell has struggled with oil theft and other security issues. Shares rose 1.5% to $71.

Write to Tess Stynes at tess.stynes@wsj.com

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