IRVINE, Calif., Sept. 22, 2021 /PRNewswire/ -- Today Zymo
Research announced its EZ DNA Methylation-Lightning Kit™
has received the CE IVD Mark allowing the technology to be
distributed within the European Union (EU) common market. Chemical
treatment of DNA with bisulfite is the prerequisite for many
methylation-based diagnostic assays. Clinical diagnostic and
screening tests, particularly those for cancer and developmental
diseases, are now utilizing methylation profiling of DNA to detect
the presence of disease and guide treatment.
The established, proven bisulfite-treatment chemistry from Zymo
Research has been highly successful with clinical samples due to
its robust and efficient (C)ytosine to (U)rasil conversion
chemistry that also minimizes DNA fragmentation and degradation
during the process. Desulphonation and cleanup of "converted DNA"
are performed using a unique spin technology, allowing ultra-low
elution (10 µl) volumes. The kit achieves the highest conversion
efficiencies for the most accurate downstream methylation analysis.
The EZ DNA Methylation-Lightning Kit features a ready-to-use
conversion reagent, which streamlines the workflow for completion
in a little over an hour. The kit is available in spin-column and
high-throughput 96-well formats.
"The scientists at Zymo Research are always working to
streamline and simplify workflows for our customers. The EZ DNA
Methylation-Lightning Kit is one example of this philosophy," said
Marc Van Eden, Zymo Research's Vice
President of Business Development. "The kit consolidates many of
the labor-intensive steps required for precise, complete bisulfite
conversion of DNA making an otherwise cumbersome workflow
user-friendly and consistent time after time. This is particularly
critical for assay reproducibility in sensitive analytical
processes such as Next-Gen sequencing."
For more information about the EZ DNA Methylation-Lightning Kit,
visit Zymo Research's website.
About Zymo Research Corp.
Zymo Research is a privately owned company that has been serving
the scientific and diagnostics community with state-of-the-art
molecular biology tools since 1994. The company's vision "The
Beauty of Science is to Make Things Simple" is reflected in all of
their products, from epigenetics to DNA/RNA purification
technologies. Historically recognized as the leader in epigenetics,
Zymo Research is breaking boundaries with novel solutions for
sample collection, microbiomic measurements, diagnostic devices,
and NGS technologies that are high quality and simple to use.
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Instagram.
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SOURCE Zymo Research Corp.