- The Psoriasis Market enlarges vigorously with surging
demand for the upcoming therapies, changing lifestyle,
increasing disposable income, and higher adult
population.
LAS VEGAS, May 11, 2021 /PRNewswire/ -- DelveInsight's
"Psoriasis Market" report provides a thorough comprehension of the
Psoriasis, historical and forecasted epidemiology, and the
Psoriasis market trends in the 7MM [the
United States, EU5 (Germany, Spain, Italy,
France, and United Kingdom) and Japan]. The Psoriasis market report also
proffers an analysis of the current Psoriasis treatment
algorithm/practice, market drivers, market barriers, and unmet
medical needs.
Some of the imperative takeaways of the Psoriasis Market
Research Report
- A slew of companies such as Dermavant Sciences,
Abbvie, Astellas Pharma, Boehringer Ingelheim,
Jiangsu HengRui Medicine, Jannsen, AstraZeneca,
Novartis, Amgen, Eli Lilly and Company, UCB Pharma, Akros Pharma,
Kadmon Pharmaceuticals, Pfizer, Arbor Pharmaceuticals, Dr. Reddy's
Laboratories, Bausch Health, Arcutis Biotherapeutics,
and others are developing Psoriasis therapies to influence
treatment arena.
- Biologics have emerged as highly potent treatment
options in Psoriasis patients for whom traditional systemic
therapies fail to achieve an adequate response, are not tolerated
owing to adverse effects, or are unsuitable owing to comorbidities.
The first biologic agent for the indication is the tumour
necrosis factor (TNF) antagonist etanercept (Enbrel; Amgen),
which was approved in 2004.
- Etanercept was followed by two other TNF inhibitors in
the Psoriasis market: infliximab (Remicade; Merck &
Co./Janssen Biotech) in 2006 and adalimumab (Humira; AbbVie) in
2008. Humira and Enbrel further got their label
expanded, including the fingernail psoriasis in adults in
2017 and plaque psoriasis in children aged 4-17 in
2016, respectively for, Humira and Enbrel.
- The latest entry in the anti-TNF market for Psoriasis has been
CImizia (UCB), approved by the FDA in 2018. Cimzia is
the first Fc-free biologic of its kind approved by the FDA to treat
adults with moderate-to-severe plaque psoriasis who are candidates
for systemic therapy or phototherapy.
- Ustekinumab (Stelara; Janssen Biotech), which binds to
the p40 subunit that is common to both IL-12 and IL-23, was
approved by the US Food and Drug Administration (FDA) in
2009, whereas secukinumab (Cosentyx; Novartis) was
approved by the FDA in January
2015 as the first IL-17A-specific humanized monoclonal
antibody (mAb) for the systemic treatment of moderate-to-severe
psoriasis.
- The FDA has approved two more therapies targeting
interleukin-17 (IL-17) receptors, namely Siliq (brodalumab) and
Taltz (ixekizumab).
- The IL-23 molecules are the latest and improved treatment line
for Psoriasis, while IL-17, IL-12/23, TNF-Alpha, and conventional
oral medicine are older methods of treatment. IL-23 has an efficacy
advantage over the anti-TNF molecules, and this will help expand
Psoriasis market share at a faster pace. Tremfya (guselkumab;
Janssen), approved in 2017, became the first approved
biologic therapy that particularly stops only IL-23, a cytokine
that plays a vital role in Plaque Psoriasis.
- The approval of Ilumya (tildrakizumab-asmn; Sun Pharma)
in 2018 marked the second approval in the IL-23 molecules.
The latest entry into the IL-23 molecules category is Skyrizi
(risankizumab-rzaa; AbbVie) and was approved in 2019 by the FDA
for the treatment of moderate to Severe Plaque Psoriasis in adults
who are candidates for systemic therapy or phototherapy.
- For more severe psoriasis, phototherapy combined with systemic
oral drugs such as methotrexate, acitretin, or cyclosporine is
typically prescribed. The anti-inflammatory drug apremilast
(Otezla; Celgene), a phosphodiesterase 4 (PDE4) inhibitor,
became the first new oral Psoriasis treatment. It was approved in
the United States in
September 2014 and
Europe in January 2015.
- The Psoriasis pipeline scenario for topical therapies presents
three candidates, out of which Tapinarof and ARQ-151
are in the phase III stage, whereas PF-06700841 is
currently in the phase II stage of clinical
development.
- The Psoriasis pipeline is showing early promise with several
therapeutic candidates at different stages of clinical development.
Many new Psoriasis therapies are in development, many of which have
novel targets and mechanisms of action.
For further information on Market Impact by Therapies,
visit: Psoriasis Drug Market Analysis
Psoriasis is a chronic, immune-mediated inflammatory skin
disease that is characterized by the presence of papules and
plaques occurring mostly on the elbows, knees, scalp, and lower
back, but is not limited to these areas.
According to DelveInsight's estimates, Psoriasis affects males
and females equally globally. The total prevalent cases of
Psoriasis in adults in the United
States were 8,241,909 cases in 2020. There were
6,593,527 cases for mild to moderate Psoriasis and
1,648,382 cases for moderate to severe Psoriasis in
the same year.
The Psoriasis Market Report provides historical
as well as forecasted epidemiological analysis segmented
into:
- Prevalence of Psoriasis in Pediatrics
- Prevalence of Psoriasis in Adults
- Type-specific Prevalent Cases of Psoriasis
- Severity-specific Prevalent Cases of Psoriasis
- Location-specific Prevalent Cases of Psoriasis
Get a sample copy of this report: Psoriasis Market Size
Landscape
Psoriasis Treatment Market
Although there is no cure for Psoriasis, there are multiple
effective treatment options. Topical therapies have been the
first-line choice for the Psoriasis treatment, mainly mild to
moderate cases and are applied to the skin. Topicals decrease or
normalize excessive cell reproduction and lessen inflammation
caused by Psoriasis. There are various effective treatment
therapies for the disease, many of which can be purchased over the
counter (OTC). Nevertheless, some therapies are only available by
prescription from the health care provider.
A range of agents is available for the symptomatic treatment of
Psoriasis. Patients with mild-to-moderate Psoriasis usually receive
topical treatments that modulate gene transcription, inhibit cell
proliferation and promote keratinocyte differentiation. These cases
can be treated topically with a combination of glucocorticoids,
vitamin D analogues, and phototherapy.
Major topical agents include corticosteroids, retinoids
(tazarotene), and calcineurin inhibitors (tacrolimus), vitamin D
analogues (calcipotriene or calcitriol), and combinations
(calcipotriol plus betamethasone dipropionate).
Calcipotriol/betamethasone dipropionate cutaneous foam halobetasol
propionate, and tazarotene has expanded the treatment options of
topical therapy in several countries.
Psoriasis market dynamics will be drifted positively in the
coming years due to the expected launch of emerging therapies
during the forecast period of 2020–2030, as there are several
shortcomings in the pharmacologic treatment available to treat
Psoriasis patients. Several companies across the globe are
thoroughly working toward the development of new treatments and
devices.
Psoriasis Emerging Therapies Along with Key
Players
- Bimekizumab (UCB4940): UCB Pharma
- Mirikizumab: Eli Lilly and Company
- Tapinarof (DVMT-505): Dermavant Sciences
- ARQ-151: Arcutis Biotherapeutics
- Deucravacitinib (BMS-986165): Bristol-Myers Squibb
- PF-06826647: Pfizer
- Sonelokimab: Avillion / Merck
- PPC-06: Arbor Pharmaceuticals/Dr. Reddy's Laboratories
- KD025: Kadmon Pharmaceuticals
- PF-06700841 (Brepocitinib): Pfizer
- BI 730357: Boehringer Ingelheim
- JTE-451: Akros Pharma
And several others.
Scope of the Psoriasis Market Insight
Report
- Geography Covered: The United
States, EU5 (Germany,
France, Italy, Spain,
and the United Kingdom), and
Japan.
- Study Period: 3-year historical and 10-year forecasted
analysis (2018-2030).
- Psoriasis Markets Segmentation: By
Geographies and By Psoriasis Therapies
(Historical and Forecasted, Current and Upcoming)
- Dominant Market Companies investigating its candidates
for Psoriasis: Dermavant Sciences, Abbvie,
Astellas Pharma, Boehringer Ingelheim, Jiangsu HengRui Medicine,
Jannsen, AstraZeneca, Novartis, Amgen, Eli Lilly and Company, UCB
Pharma, Akros Pharma, Kadmon Pharmaceuticals, Pfizer, Arbor
Pharmaceuticals, Dr. Reddy's Laboratories, Bausch Health, Arcutis
Biotherapeutics, and several others.
- Analysis: Comparative and conjoint analysis of emerging
therapies.
- Case Studies
- KOL's Views
- Analyst's View
Request for a Webex demo of the report @ Psoriasis
Treatment Market Size
Table of Contents
1
|
Psoriasis Key
Insights
|
2
|
Executive Summary
of Psoriasis
|
3
|
SWOT Analysis for
Psoriasis
|
4
|
Psoriasis Market
Overview at a Glance
|
5
|
Psoriasis Disease
Background and Overview
|
6
|
Psoriasis
Epidemiology and Patient Population
|
7
|
Total Diagnosed
Psoriasis Prevalent Population
|
8
|
Country
Wise-Epidemiology of Psoriasis
|
8.1
|
The United
States
|
8.2
|
EU5
Countries
|
8.2.1
|
Germany
|
8.2.2
|
France
|
8.2.3
|
Italy
|
8.2.4
|
Spain
|
8.2.5
|
The United
Kingdom
|
8.3
|
Japan
|
9
|
Psoriasis
Treatment and Management
|
10
|
Psoriasis Unmet
Needs
|
11
|
Psoriasis Marketed
Drugs
|
11.1
|
Humira:
Abbvie
|
11.2
|
Stelara:
Jannsen
|
12
|
Psoriasis Emerging
Therapies
|
12.1
|
Tapinarof (DVMT-505):
Dermavant Sciences
|
13
|
7MM Psoriasis
Market Analysis
|
14
|
Psoriasis Market
Outlook by Country
|
14.1
|
The United States
Psoriasis Market Size
|
14.2
|
EU-5 Psoriasis
Market Size
|
14.2.1
|
Germany Market
Size
|
14.2.2
|
France Market
Size
|
14.2.3
|
Italy Market
Size
|
14.2.4
|
Spain Market
Size
|
14.2.5
|
The United Kingdom
Market Size
|
14.3
|
Japan Psoriasis Market
Size
|
15
|
Psoriasis Market
Drivers
|
16
|
Psoriasis Market
Barriers
|
17
|
Psoriasis Market
Access and Reimbursement
|
18
|
Appendix
|
19
|
DelveInsight
Capabilities
|
20
|
Disclaimer
|
21
|
About
DelveInsight
|
Browse full report with detailed TOC with charts, figures,
tables @ Psoriasis Market Share Report
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