IQ-AI Limited IB Broadens Quantitative Mapping (1476K)
May 03 2022 - 9:21AM
UK Regulatory
TIDMIQAI
RNS Number : 1476K
IQ-AI Limited
03 May 2022
3 May 2022
IQ-AI Ltd
("IQ-AI" or the "Company")
IB Neuro's Quantitative Mapping Method Assesses Metastatic
Tumors
Study Shows DSC MRI Perfusion Distinguishes Tumor from Non-Tumor
Tissue
Milwaukee - 3 May 2022: Imaging Biometrics, LLC (IB), a
subsidiary of IQ-AI Limited, (OTCQB: IQAIF) (LSE: IQAI), notes a
recent study published in the American Journal of Neuroradiology
entitled: DSC Perfusion-Derived Fractional Tumor Burden and
Relative CBV Differentiate Tumor Progression and Radiation Necrosis
in Brain Metastases Treated with Stereotactic Radiosurgery.
The retrospective study, led by Dr. Michael Iv, MD, Clinical
Associate Professor at Stanford University, used IB Software and
other advanced imaging methods to evaluate metastatic brain tumors
previously treated with a very precise form of radiation therapy
called stereotactic radiosurgery. The goal was to determine which,
if any, imaging technology could reliably distinguish between
progressive tumor and radiation necrosis (non-tumor) tissue. The
study concluded that IB Neuro's dynamic susceptibility contrast
magnetic resonance imaging (DSC-MRI) perfusion-derived maps were
able to make this distinction whereas the other methods to which it
was compared could not. Those other methods included dynamic
contrast enhanced (DCE) imaging, arterial spin labeling (ASL) which
is an MRI technique that uses the body's own blood as a contrast
agent to compute blood flow measurements, and positron emission
tomography (PET) which can detect metabolic differences in
tissue.
DSC-MRI is well established as the most robust and clinically
adopted method for response assessment in high-grade (HG) primary
brain tumors. Numerous studies have demonstrated the accuracy and
reproducibility of IB Neuro's DSC platform and, specifically, its
standardized measurement of relative cerebral blood volume (rCBV)
to distinguish tumor from non-tumor tissue in HG tumors. This study
is the first to replicate this method in metastatic brain tumors.
The results are positive news for treatment teams who currently
must rely on contrast-enhanced MRI to answer the basic question -
is the enhancing region tumor, or is it an effect due to
treatment?
Metastatic brain tumors are ten times more prevalent than
primary brain tumors. This year in the US alone, it is expected
that 220,000 people will be diagnosed with a metastatic brain
cancer. Moreover, advances in treatment therapy are helping
metastatic brain tumor patients live longer with improved quality
of life. Thus, this number is expected to increase over time. Up to
50% of all cancers will eventually metastasize to the brain.
The study referred to IB's standardized rCBV (sRCBV)
measurement. Standardization is an exclusive calibration technology
that is built-in to IB Neuro. Fully automated, standardization
translates the relative MRI image intensities to a fixed and
consistent quantitative scale. This machine-learned technology is
applied once for all scanner platforms, field strengths, and
patients, and enables direct quantitative comparison between scans.
It has been shown superior over other tissue normalization
techniques; all of which require manual user input and are,
therefore, less consistent and cannot be automated. The ability to
obtain quantitative sRCBV values on a per-voxel basis
differentiates IB Neuro from all other DSC-MRI platforms.
"This relevant and powerful study further validates our decision
to develop IB Trax(TM). Incorporating our quantitative Delta T1
(patent-pending) and sRCBV maps will help neuroradiologists track
and monitor brain metastases over time and potentially boost their
accuracy and efficiency," said Trevor Brown, CEO and Chairman of
IQ-AI, Ltd.
The Directors of the Company accept responsibility for the
contents of this announcement
-ENDS-
For further information, please contact:
IQ-AI Limited
Trevor Brown/Brett Skelly/Vinod Kaushal
Tel: 020 7469 0930
Peterhouse Capital Limited (Financial Adviser and Broker)
Lucy Williams/Heena Karani
Tel: 020 7220 9797
About IQ-AI Limited
IQ-AI Limited, (LON: IQAI) (OTCQB: IQAIF), the parent company of
Wisconsin-based Imaging Biometrics, LLC (IB), develops and provides
visualisation and analytical solutions that enable clinicians to
better diagnose and treat disease with greater confidence. Through
close collaboration with top researchers and clinicians,
sophisticated advancements are translated into platform-independent
and automated software plug-ins which can extend the base
functionality of workstations, imaging systems, PACS, or medical
viewers. By design, IB's advanced visualisation software seamlessly
integrates into routine workflows. For more information about
Imaging Biometrics, visit the company's website at
www.imagingbiometrics.com
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END
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