THE BIOTECH GROWTH TRUST PLC

NET ASSET VALUE

The estimated un-audited net asset value per share, calculated in accordance with the guidelines of the Association of Investment Companies, for The Biotech Growth Trust PLC at the close of business on 1 December 2021 was 1156.34p (ex income) 1156.30p (cum income).

For and on behalf of the Board

Frostrow Capital LLP

Secretary

02 December 2021

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